Effect of ursolic acid treatment on apoptosis and DNA damage in isoproterenol-induced myocardial infarction

Biochimie

Volumn 94, Issue 5, 2012, Pages 1135-1142

  Radhiga, Thangaiyan ^a   Rajamanickam, Chellam ^b   Sundaresan, Arjunan ^a   Ezhumalai, Muthukrishnan ^a   Pugalendi, Kodukkur Viswanathan ^a  

^a ANNAMALAI UNIVERSITY   (India)

^b Osho Biotech Research Institute   (India)

Author keywords

Antioxidant; Apoptosis; Cardiac markers; DNA damage; Ursolic acid

Indexed keywords

ALKADIENE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BIOLOGICAL MARKER; CASPASE 3; CASPASE 8; CASPASE 9; CATALASE; CREATINE KINASE MB; CYTOCHROME C; FAS ANTIGEN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; ISOPRENALINE; LIPID HYDROPEROXIDE; MITOCHONDRIAL PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TROPONIN I; TROPONIN T; TUMOR NECROSIS FACTOR ALPHA; URSOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; B CELL LYMPHOMA; CONTROLLED STUDY; DNA FRAGMENTATION; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INDUCTION; ERYTHROCYTE; HEART; HEART INFARCTION; HISTOPATHOLOGY; LIPID PEROXIDATION; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; DNA DAMAGE; DNA FRAGMENTATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ISOPROTERENOL; MALE; MYOCARDIAL INFARCTION; RATS; RATS, WISTAR; TRITERPENES;

RATTUS;

EID: 84859429502     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2012.01.015     Document Type: Article

References (79)

1. W.S. Aronow Epidemiology, pathophysiology, prognosis and treatment of systolic and diastolic heart failure Cardiol. Rev. 14 3 2006 108 124
2. - production Thromb. Haemost. 90 2 2003 317 325
3. T. Nakamura, H. Nishi, Y. Kokusenya, K. Hirota, and Y. Miura Mechanism of antioxidative activity of fluvastatin determination of the active position Chem. Pharm. Bull. 48 2 2000 235 237
4. M. Dikshit, M.H. Van Oosten, S. De Graff, and R.C. Srimal Free radical scavenger mechanisms in experimentally induced ischemia in the rabbit heart and protective effect of verapamil Arch. Int. Pharmacodyn. Ther. 318 1992 55 65
5. M. Hanada, C. Aime-Sempe, T. Sato, and J.C. Reed Structure-function analysis of Bcl-2 protein. Identification of conserved domains important for homodimerization with Bcl-2 and heterodimerization with Bax J. Biol. Chem. 270 20 1995 11962 11969
6. Z.N. Oltvai, C.L. Milliman, and S.J. Korsmeyer Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death Cell 74 4 1993 609 619
7. T. Miyashita, S. Krajewski, M. Krajewska, H.G. Wang, H.K. Lin, D.A. Liebermann, B. Hoffman, and J.C. Reed Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo Oncogene 9 6 1994 1799 1805
8. E. Yang, J. Zha, J. Jockel, L.H. Boise, C.B. Thompson, and S.J. Korsmeyer Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death Cell 80 2 1995 285 291
9. D.M. Hockenbery, M. Zutter, W. Hickey, M. Nahm, and S.J. Korsmeyer Bcl-2 protein is topographically restricted in tissues characterized by apoptotic cell death Proc. Natl. Acad. Sci. 88 16 1991 6961 6965
10. S.J. Korsmeyer Bcl-2 initiates a new category of oncogenes: regulators of cell death Blood 80 4 1992 879 886
11. D.M. Hockenbery, Z.N. Oltvai, X.M. Yin, C.L. Milliman, and S.J. Korsmeyer Bcl-2 functions in an antioxidant pathway to prevent apoptosis Cell 75 2 1993 241 251
12. T.E. Allsopp, S. Wyatt, H.F. Paterson, and A.M. Davies The proto-oncogene Bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis Cell 73 2 1993 295 307
13. M. Higuchi, T. Honda, R.J. Proske, and E.T. Yeh Regulation of reactive oxygen species-induced apoptosis and necrosis by caspase-3 like proteases Oncogene 17 21 1998 2753 2760
14. T. Tsuruta, K. Oh-hashi, K. Kiuchi, and Y. Hirata Degradation of caspase-activated DNase by the ubiquitin-proteasome system Biochim. Biophys. Acta 1780 5 2008 793 799
15. S.B. Mahato, S.K. Sarkar, and G. Poddar Triterpenoidsaponins Phytochemistry 27 1988 3037 3067
16. J.H. Chen, Z.H. Xia, and R.X. Tan High performance liquid chromatographic analysis of bioactive triterpenes in Perilla frutescens J. Pharm. Biomed. Anal. 32 6 2003 1175 1179
17. J. Liu Pharmacology of oleanolic acid and ursolic acid J. Ethanopharmacol. 49 2 1995 57 68
18. P.O. Harmand, R. Duval, C. Delage, and A. Simon Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells Int. J. Cancer 114 1 2005 1 11
19. J. Liu Oleanolic acid and ursolic acid: research perspectives J. Ethnopharmacol. 100 1-2 2005 92 94
20. Y.H. Shih, Y.C. Chein, J.Y. Wang, and Y.S. Fu Ursolic acid protects hippocampal neurons against kainate-induced excitotoxicity in rats Neurosci. Lett. 362 2 2004 136 140
21. L.O. Somova, A. Nadar, P. Rammanan, and F.O. Shode Cardiovascular, antihyperlipidemic and antioxidant effect of oleanolic acid and ursolic acid in experimental hypertension Phytomedicine 10 2-3 2003 115 121
22. L.I. Somova, F.O. Shode, and M. Mipando Cardiotonic and antidysrhythmic effects of oleanolic acid and ursolic acids, methyl maslinate and uvaol Phytomedicine 11 2-3 2004 121 129
23. R. Saravanan, P. Viswanathan, and K.V. Pugalendi Protective effect of ursolic acid on ethanol mediated experimental liver damages in rats Life Sci. 78 7 2006 713 718
24. J. Lu, Y.L. Zheng, D.M. Wu, L. Luo, D.X. Sun, and Q. Shan Ursolic acid ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by D-galactose Biochem. Pharmacol. 74 7 2007 1078 1090
25. S.D. Seth, M. Maulik, C.K. Katiyar, and S.K. Maulik Role of Lipistat in protection against isoproterenol-induced myocardial necrosis in rats: a biochemical and histopathological study Ind. J. Physiol. Pharmacol. 42 1 1998 101 106
26. H.A. Katus, A. Remppis, F.J. Neumann, T. Scheffold, K.W. Diederich, G. Vinar, A. Noe, G. Matern, and W. Kuebler Diagnostic efficacy of troponin T measurements in acute myocardial infarction Circulation 83 3 1991 902 912
27. C. Larue, C. Calzolari, J.P. Bertinchant, F. Leclercq, R. Grolleau, and B. Pau Cardiac-specific immunoenzymomimetic assay of troponin I in the early phase of acute myocardial infarction Clin. Chem. 39 6 1993 972 979
28. W.G. Niehaus Jr., and B. Samuelson Formation of malondialdehyde from phospholipid arachidonate during microsomal lipid peroxidation Eur. J. Biochem. 6 1 1968 126 130
29. Z.Y. Jiang, J.V. Hunt, and S.P. Wolff Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxide in low density lipoprotein Anal. Biochem. 202 1992 384 389
30. K.S. Rao, and R.O. Recknagel Early onset of lipid peroxidation in rat liver after carbon tetrachloride administration Exp. Mol. Pathol. 9 2 1968 271 278
31. J.H. Roe, and C.A. Kuether The determination of ascorbic acid in whole blood and urine through the 2,4-dinitrophenylhydrazine derivative of dehydroascorbic acid J. Biol. Chem. 11 1943 145 164
32. H. Baker, O. Frank, B. De Angelis, and S. Feingold Plasma α-tocopherol in man at various times after ingesting free or acetylated tocopherol Nutr. Res. 21 1980 531 536
33. G.L. Ellman Tissue sulfhydryl groups Arch. Biochem. Biophys. 82 1959 70 77
34. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with Folin phenol reagent J. Biol. Chem. 193 1 1951 265 275
35. P. Kakkar, B. Das, and P.N. Viswanathan A modified spectrophotometric assay of superoxide dismutase Ind. J. Biochem. Biophys. 21 2 1984 130 132
36. A.K. Sinha Colorimetric assay of catalase Anal. Biochem. 47 2 1972 389 394
37. J.T. Rotruck, A.L. Pope, H.E. Ganther, A.B. Swanson, D.G. Hafeman, and W.G. Hoekstra Selenium: biochemical role as a component of glutathione peroxidise Science 179 1973 588 590
38. W.H. Habig, M.J. Pabst, and W.B. Jakoby Glutathione-S-transferases: the first enzymatic step in mercapturic acid formation J. Biol. Chem. 249 1974 7130 7139
39. R.E. Pinto, and W. Bartley The effect of age and sex on glutathione reductase and glutathione peroxidase activities on aerobic glutathione oxidation in rat liver homogenate Biochem. J. 112 1969 109 115
40. M.J. Hebert, T. Takano, H. Holthofer, and H.R. Brady Sequential morphologic events during apoptosis of human neutrophils. Modulation by lipoxygenase-derived eicosanoids J. Immunol. 157 1996 3105 3115
41. U.K. Laemmli Cleavge of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 5259 1970 680 685
42. J. Mair Cardiac troponin I and troponin T: are enzymes still relevant as cardiac markers? Clin. Chim. Acta 257 1 1997 99 115
43. G.A. Kurian, S. Philips, and T. Varghese Effect of aqueous extract of the Desmodium gangeticum DC root in the severity of myocardial infarction J. Ethanopharmacol 97 3 2005 457 461
44. C.W. Hamm, and E. Braunwald A classification of unstable angina revisited Circulation 102 2000 118 122
45. S. Kasap, A. Gonenc, D.E. Sener, and I. Hisar Serum cardiac markers in patients with acute myocardial infarction: oxidative stress, C-reactive protein and N-terminal probrain natriuretic peptide J. Clin. Biochem. Nutr. 41 1 2007 50 57
46. S. Gupta, K.N. Singh, V. Bapat, V. Mishra, D.K. Agarwal, and P. Gupta Diagnosis of acute myocardial infarction: CK-MB versus cTn-T in Indian patients Ind. J. Clin. Biochem. 23 1 2008 89 91
47. M. Hamberg, J. Svensson, T. Wakabayashi, and B. Samuelsson Isolation and structure of two prostaglandins endoperoxides that cause platelet aggregation Proc. Natl. Acad. Sci. 71 1974 345 349
48. F.A. Resende, C.A.M.A. Barcala, M.C.S. Faria, F.H. Kato, W.R. Cunha, and D.C. Tavares Antimutagenicity of ursolic and oleanoic acid against doxorubicin-induced clastogenesis in Balb/c mice Life Sci. 79 2006 1268 1273
49. M. Sharma, K. Kishore, S.K. Gupta, S. Joshi, and D.S. Arya Cardioprotective potential of Ocimum sanctum in isoproterenol induced myocardial infarction in rats Mol. Cell Biochem. 225 1 2001 75 83
50. S. Balanehru, and B. Nagarajan Protective effect of oleanolic acid and ursolic acid against lipid peroxidation Biochem. Int. 24 5 1991 981 990
51. H.C. Benohr, and H.D. Waller L. Flohe, H.C. Benohr, H. Sies, H.D. Waller, A. Wendel, Glutathione 1974 Georg Thieme Stuttgart 184 191
52. B.V. Ommen, J.H.T.M. Ploemen, J.J.P. Bogaards, T.J. Monks, S.S. Gau, and P.J.V. Bladeren Irreversible inhibition of rat glutathione S-transferase 1-1 by quinones and their glutathione conjugates, structure-activity relationship and mechanism Biochem. J. 276 3 1991 661 666
53. D.R. Janero Therapeutic potential of vitamin E against myocardial ischemic-reperfusion injury Free Radic. Biol. Med. 10 5 1991 315 324
54. H. Wefers, and H. Sies The protection by ascrobate and glutathione against microsomal lipid peroxidation is dependent on vitamin E Eur. J. Biochem. 174 2 1988 353 357
55. A. Meister New aspects of glutathione biochemistry and transport selective alterations of glutathione metabolism Nutr. Rev. 42 1984 397 400
56. J.L. Lil, F.W. Stantman, and H.A. Lardy Antioxidant enzyme systems in rat liver and skeletal muscle Arch. Biochem. Biophys. 263 1988 150 156
57. D.F. Mangan, S.E. Mergenhagen, and S.M. Wahl Apoptosis in human monocytes: possible role in chronic inflammatory diseases J. Periodontol. 64 5 1993 461 466
58. Q. Tang, P.B. Taylor, and R.K. Helbing Catecholamine induced cardiac hypertrophy Can. J. Cardiol. 3 6 1987 311 316
59. A.S. Galvez, J.L. Fiedler, M.P. Ocaranza, J.E. Jalil, S. Lavandero, and G. Diaz-Araya Perindopril regulates beta-agonist-induced cardiac apoptosis J. Cardiovasc. Pharmacol. 46 3 2005 255 261
60. R. Gabbianelli, C. Nasuti, G. Falcioni, and F. Cantalamessa Lymphocyte DNA damage in rats exposed to pyrethroids: effect of supplementation with vitamins E and C Toxicol 203 1-3 2004 17 26
61. B.W. Jeon, K.T. Kim, S.I. Chang, and H.Y. Kim Phosphoinositide 3-OH kinase/protein kinase B inhibits apoptotic cell death induced by reactive oxygen species in Saccharomyces cerevisiae J. Biochem. 131 5 2002 693 699
62. S. Kang, Y.J. Yang, Y.L. Wu, Y.T. Chen, L. Li, and Y. Tian Myocardium and microvessel endothelium apoptosis at day 7 following reperfused acute myocardial infarction Microvasc. Res. 79 1 2010 70 79
63. G. Takemura, and H. Fujiwara Role of apoptosis in remodeling after myocardial infarction Pharmacol. Ther. 104 1 2004 1 16
64. B. Murtuza, K. Suzuki, G. Bou-Gharios, J.R. Beauchamp, R.T. Smolenski, T.A. Partridge, and M.H. Yacoub Transplantation of skeletal myoblasts secreting an IL-1 inhibitor modulates adverse remodeling in infarcted murine myocardium Proc. Natl. Acad. Sci. 101 12 2004 4216 4221
65. J.M. Adams, and S. Cory The Bcl-2 protein family: arbiters of cell survival Science 281 5381 1998 1322 1326
66. L.A. Kirshenbaum, and D. De Moissac The bcl-2 gene product prevents programmed cell death of ventricular myocytes Circulation 96 5 1997 1580 1585
67. G.M. Cohen Caspases: the executioners of apoptosis Biochem. J. 326 1 1997 1 16
68. S.B. Bratton, and G.M. Cohen Apoptotic death sensor: an organelle's alter ego? Trends Pharmacol. Sci. 22 6 2001 306 315
69. J.G. Burniston, L.B. Tan, and D.F. Goldspink β-Adrenergic receptor stimulation in vivo induces apoptosis in the rat heart and soleus muscle J. Appl. Physiol. 98 4 2005 1379 1386
70. R.W. Saeed, T. Peng, and C.N. Metz Ascorbic acid blocks the growth inhibitory effect of TNF-α on endothelial cell Exp. Biol. Med. 228 7 2003 855 865
71. P.P. Simeonova, and M.I. Luster Iron and reactive oxygen species in the asbestos-induced tumor necrosis factor-alpha response from alveolar macrophages Am. J. Respir. Cell Mol. Biol. 12 6 1995 676 683
72. S. Agarwal, and N.P. Piersco Poly ADP-ribosylation of a 90 kDa protein is involved in TNF-α mediated cytotoxicity J. Immunol. 153 2 1994 473 481
73. P. Lee, M. Sata, D.J. Lefer, S.M. Factor, Walsh, and K.R.N. Kitsis Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo Am. J. Physiol. Heart Circ. Physiol. 284 2 2003 456 463
74. L. Gomez, N. Chavanis, L. Argaud, L. Chalabreysse, O. Gateau-Roesch, J. Ninet, and M. Ovize Fas-independent mitochondrial damage triggers cardiomyocyte death after ischemia-reperfusion Am. J. Physiol. Heart Circ. Physiol. 289 5 2005 2153 2158
75. N. Itoh, S. Yonehara, A. Ishii, M. Yonehara, S. Mizushima, M. Sameshima, A. Hase, Y. Seto, and S. Nagata The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis Cell 66 2 1991 233 243
76. T. Suda, T. Takahashi, P. Golstein, and S. Nagata Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family Cell 75 6 1993 1169 1178
77. G.S. Salvesen, and S.J. Riedl Structure of the Fas/FADD complex: a conditional death domain complex mediating signaling by receptor clustering Cell Cycle 8 17 2009 2723 2727
78. A. Strasser, P.J. Jost, and S. Nagata The many roles of FAS receptor signalling in the immune system Immunity 30 2 2009 180 192
79. Y.Z. Zhu, Y.C. Zhu, Z.J. Wang, Q. Lu, H.S. Lee, and T. Unger Time-dependent apoptotic development and pro-apoptotic genes expression in rat heart after myocardial infarction Jpn. J. Pharmacol. 86 3 2001 355 358