Monoubiquitination of pro-amphiregulin regulates its endocytosis and ectodomain shedding

Biochemical and Biophysical Research Communications

Volumn 420, Issue 2, 2012, Pages 315-320

  Fukuda, Shinji ^a   Nishida Fukuda, Hisayo ^a   Nakayama, Hironao ^a   Inoue, Hirofumi ^a,b,c   Higashiyama, Shigeki ^a,c  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Ehime Nikon Bio Imaging Core Laboratory   (Japan)

^c EHIME UNIVERSITY   (Japan)

Author keywords

Amphiregulin; Ectodomain shedding; Epidermal growth factor receptor; Ubiquitination

Indexed keywords

AMPHIREGULIN; CHIMERIC PROTEIN; LYSINE; PHORBOL 13 ACETATE 12 MYRISTATE; PRO AMPHIREGULIN; UNCLASSIFIED DRUG;

ARTICLE; BIOTINYLATION; CELL MIGRATION; CELL ORGANELLE; CELL SECRETION; CELL SURFACE; CELLULAR DISTRIBUTION; ECTODOMAIN SHEDDING; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVE SITE; HALF LIFE TIME; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN DOMAIN; REGULATORY MECHANISM; UBIQUITINATION; WILD TYPE;

CELL LINE, TUMOR; ENDOCYTOSIS; GLYCOPROTEINS; HALF-LIFE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYSINE; PROTEIN TRANSPORT; RECEPTOR, EPIDERMAL GROWTH FACTOR; UBIQUITINATION;

EID: 84859427647     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.02.156     Document Type: Article

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