Effects of tempol and candesartan on neural control of the kidney

Autonomic Neuroscience: Basic and Clinical

Volumn 168, Issue 1-2, 2012, Pages 48-57

  Eppel, Gabriela A ^a   Head, Geoffrey A ^b   Denton, Kate M ^a   Evans, Roger G ^a  

^a MONASH UNIVERSITY   (Australia)

^b BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

Angiotensin; Kidney; Superoxide dismutase; Sympathetic nervous system

Indexed keywords

ANGIOTENSIN II; CANDESARTAN; SODIUM; SUPEROXIDE DISMUTASE; TEMPOL;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG RESPONSE; EXPERIMENTAL RABBIT; GLOMERULUS FILTRATION RATE; KIDNEY; KIDNEY ARTERY; KIDNEY BLOOD FLOW; KIDNEY NERVE; KIDNEY TUBULE EXCRETION; MALE; NERVE STIMULATION; NONHUMAN; OBESITY; PRIORITY JOURNAL; SODIUM EXCRETION; VASOCONSTRICTION; VASODILATATION;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; ANTIOXIDANTS; BENZIMIDAZOLES; BLOOD PRESSURE; CYCLIC N-OXIDES; DIET; DIET, HIGH-FAT; DINOPROST; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; HEART RATE; HEMATOCRIT; KIDNEY; KIDNEY FUNCTION TESTS; MALE; OBESITY; RABBITS; RENAL CIRCULATION; SPIN LABELS; SUPEROXIDES; TETRAZOLES; URODYNAMICS;

EID: 84859423821     PISSN: 15660702     EISSN: 18727484     Source Type: Journal    
DOI: 10.1016/j.autneu.2012.01.007     Document Type: Article

References (55)

1. Ando K., Fujita T. Metabolic syndrome and oxidative stress. Free Radic. Biol. Med. 2009, 47:213-218.
2. Campese V.M., Ye S., Zhong H., Yanamadala V., Ye Z., Chiu J. Reactive oxygen species stimulate central and peripheral sympathetic nervous system activity. Am. J. Physiol. Heart Circ. Physiol. 2004, 287:H695-H703.
3. Chung S., Park C.W., Shin S.J., Lim J.H., Chung H.W., Youn D.Y., Kim H.W., Kim B.S., Lee J.H., Kim G.H., Chang Y.S. Tempol or candesartan prevents high-fat diet-induced hypertension and renal damage in spontaneously hypertensive rats. Nephrol. Dial. Transplant. 2010, 25:389-399.
4. de Richelieu L.T., Sorensen C.M., Holstein-Rathlou N.H., Salomonsson M. NO-independent mechanism mediates tempol-induced renal vasodilation in SHR. Am. J. Physiol. Renal Physiol. 2005, 289:F1227-F1234.
5. DiBona G.F., Sawin L.L. Losartan corrects abnormal frequency response of renal vasculature in congestive heart failure. Am. J. Physiol. Heart Circ. Physiol. 2003, 285:H1857-H1863.
6. 2 receptors in the renal cortical and medullary circulations of anesthetized rabbits. Hypertension 2003, 42:200-205.
7. Dutta U.K., Lane J., Roberts L.J., Majid D.S. Superoxide formation and interaction with nitric oxide modulate systemic arterial pressure and renal function in salt-depleted dogs. Exp. Biol. Med. 2006, 231:269-276.
8. Eppel G.A., Bergstrom G., Anderson W.P., Evans R.G. Autoregulation of renal medullary blood flow in rabbits. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2003, 284:R233-R244.
9. Eppel G.A., Lee L.L., Evans R.G. alpha-Adrenoceptor subtypes mediating regional kidney blood flow responses to renal nerve stimulation. Auton. Neurosci. 2004, 112:15-24.
10. Eppel G.A., Luff S.E., Denton K.M., Evans R.G. Type 1 neuropeptide Y receptors and alpha1-adrenoceptors in the neural control of regional renal perfusion. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2006, 290:R331-R340.
11. Eppel G.A., Ventura S., Denton K.M., Evans R.G. Lack of contribution of P2X receptors to neurally mediated vasoconstriction in the rabbit kidney in vivo. Acta Physiol 2006, 186:197-207.
12. Esler M.D., Lambert E.A., Schlaich M., Navar L.G. The Dominant contributor to systemic hypertension: chronic activation of the sympathetic nervous system vs activation of the intrarenal renin-angiotensin aystem. J. Appl. Physiol. 2010, 109:1996-2002.
13. Evans R.G., Eppel G.A., Michaels S., Burke S.L., Nematbakhsh M., Head G.A., Carroll J.F., O'Connor P.M. Multiple mechanisms act to maintain kidney oxygenation during renal ischemia in anesthetized rabbits. Am. J. Physiol. Renal Physiol. 2010, 298:F1235-F1243.
14. Evans R.G., Head G.A., Eppel G.A., Burke S.L., Rajapakse N.W. Angiotensin II and neurohumoral control of the renal medullary circulation. Clin. Exp. Pharmacol. Physiol. 2010, 37:e58-e69.
15. Fujii T., Takaoka M., Ohkita M., Matsumura Y. Tempol protects against ischemic acute renal failure by inhibiting renal noradrenaline overflow and endothelin-1 overproduction. Biol. Pharm. Bull. 2005, 28:641-645.
16. Guild S.J., Malpas S.C., Eppel G.A., Nguang S.K., Evans R.G. Effect of renal perfusion pressure on responses of intrarenal blood flow to renal nerve stimulation in rabbits. Clin. Exp. Pharmacol. Physiol. 2004, 31:35-45.
17. Hall J.E., Guyton A.C., Cowley A.W. Dissociation of renal blood flow and filtration rate autoregulation by renin depletion. Am. J. Physiol. 1977, 232:F215-F221.
18. Haque M.Z., Majid D.S. Assessment of renal functional phenotype in mice lacking gp91PHOX subunit of NAD(P)H oxidase. Hypertension 2004, 43:335-340.
19. Harrison D.G., Gongora M.C. Oxidative stress and hypertension. Med. Clin. North Am. 2009, 93:621-635.
20. Just A., Olson A.J., Whitten C.L., Arendshorst W.J. Superoxide mediates acute renal vasoconstriction produced by angiotensin II and catecholamines by a mechanism independent of nitric oxide. Am. J. Physiol. Heart Circ. Physiol. 2007, 292:H83-H92.
21. Knight S.F., Yuan J., Roy S., Imig J.D. Simvastatin and tempol protect against endothelial dysfunction and renal injury in a model of obesity and hypertension. Am. J. Physiol. Renal Physiol. 2010, 298:F86-F94.
22. Kopkan L., Castillo A., Navar L.G., Majid D.S. Enhanced superoxide generation modulates renal function in ANG II-induced hypertensive rats. Am. J. Physiol. Renal Physiol. 2006, 290:F80-F86.
23. Kopkan L., Huskova Z., Vanourkova Z., Thumova M., Skaroupkova P., Cervenka L., Majid D.S. Superoxide and its interaction with nitric oxide modulates renal function in prehypertensive Ren-2 transgenic rats. J. Hypertens. 2007, 25:2257-2265.
24. Kopkan L., Majid D.S. Enhanced superoxide activity modulates renal function in NO-deficient hypertensive rats. Hypertension 2006, 47:568-572.
25. Lai E.Y., Wellstein A., Welch W.J., Wilcox C.S. Superoxide modulates myogenic contractions of mouse afferent arterioles. Hypertension 2011, 58:650-656.
26. Leonard B.L., Evans R.G., Navakatikyan M.A., Malpas S.C. Differential neural control of intrarenal blood flow. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2000, 279:R907-R916.
27. Lopez B., Salom M.G., Arregui B., Valero F., Fenoy F.J. Role of superoxide in modulating the renal effects of angiotensin II. Hypertension 2003, 42:1150-1156.
28. Ludbrook J. On making multiple comparisons in clinical and experimental pharmacology and physiology. Clin. Exp. Pharmacol. Physiol. 1991, 18:379-392.
29. Ludbrook J. Repeated measurements and multiple comparisons in cardiovascular research. Cardiovasc. Res. 1994, 28:303-311.
30. Luff S.E., Hengstberger S.G., McLachlan E.M., Anderson W.P. Distribution of sympathetic neuroeffector junctions in the juxtaglomerular region of the rabbit kidney. J. Auton. Nerv. Syst. 1992, 40:239-253.
31. Majid D.S., Kopkan L. Nitric oxide and superoxide interactions in the kidney and their implication in the development of salt-sensitive hypertension. Clin. Exp. Pharmacol. Physiol. 2007, 34:946-952.
32. Majid D.S., Nishiyama A., Jackson K.E., Castillo A. Inhibition of nitric oxide synthase enhances superoxide activity in canine kidney. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2004, 287:R27-R32.
33. Majid D.S., Nishiyama A., Jackson K.E., Castillo A. Superoxide scavenging attenuates renal responses to ANG II during nitric oxide synthase inhibition in anesthetized dogs. Am. J. Physiol. Renal Physiol. 2005, 288:F412-F419.
34. McDonald M.C., Zacharowski K., Bowes J., Cuzzocrea S., Themermann C. Tempol reduces infarct size in rodent models of regional myocardial ischemia and reperfusion. Free Rad Biol Med 1999, 27:493-503.
35. Michaels S., Eppel G.A., Burke S.L., Head G.A., Armitage J., Carroll J.F., Malpas S.C., Evans R.G. Altered responsiveness of the kidney to activation of the renal nerves in fat-fed rabbits. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2009, 296:R1889-R1896.
36. Navar L.G. The intrarenal renin-angiotensin system in hypertension. Kidney Int. 2004, 65:1522-1532.
37. Nishiyama A., Fukui T., Fujisawa Y., Rahman M., Tian R.-X., Kimura S., Abe Y. Systemic and regional hemodynamic responses to tempol in angiotensin II-infused hypertensive rats. Hypertension 2001, 37:77-83.
38. Palm F., Onozato M., Welch W.J., Wilcox C.S. Blood pressure, blood flow, and oxygenation in the clipped kidney of chronic 2-kidney, 1-clip rats: effects of tempol and angiotensin blockade. Hypertension 2010, 55:298-304.
39. Prior L.J., Eikelis N., Armitage J.A., Davern P.J., Burke S.L., Montani J.P., Barzel B., Head G.A. Exposure to a high-fat diet alters leptin sensitivity and elevates renal sympathetic nerve activity and arterial pressure in rabbits. Hypertension 2010, 55:862-868.
40. Rajapakse N.W., Eppel G.A., Widdop R.E., Evans R.G. ANG II type 2 receptors and neural control of intrarenal blood flow. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2006, 291:R1669-R1676.
41. Rajapakse N.W., Sampson A.K., Eppel G.A., Evans R.G. Angiotensin II and nitric oxide in neural control of intrarenal blood flow. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2005, 289:R745-R754.
42. Ren Y., D'Ambrosio M.A., Liu R., Pagano P.J., Garvin J.L., Carretero O.A. Enhanced myogenic response in the afferent arteriole of spontaneously hypertensive rats. Am. J. Physiol. Heart Circ. Physiol. 2010, 298:H1769-H1775.
43. 2 receptor in inflammation and oxidative stress: opposing effects in lean and obese Zucker rats. Am. J. Physiol. Renal Physiol. 2011, 300:F700-F706.
44. Sarzani R., Salvi F., Dessi-Fulgheri P., Rappelli A. Renin-angiotensin system, natriuretic peptides, obesity, metabolic syndrome, and hypertension: an integrated view in humans. J. Hypertens. 2008, 26:831-843.
45. Shokoji T., Fujisawa Y., Kimura S., Rahman M., Kiyomoto H., Matsubara K., Moriwaki K., Aki Y., Miyatake A., Kohno M., Abe Y., Nishiyama A. Effects of local administrations of tempol and diethyldithio-carbamic on peripheral nerve activity. Hypertension 2004, 44:236-243.
46. Shokoji T., Nishiyama A., Fujisawa Y., Hitomi H., Kiyomoto H., Takahashi N., Kimura S., Kohno M., Abe Y. Renal sympathetic nerve responses to tempol in spontaneously hypertensive rats. Hypertension 2003, 41:266-273.
47. Sorensen C.M., Leyssac P.P., Salomonsson M., Skott O., Holstein-Rathlou N.H. ANG II-induced downregulation of RBF after a prolonged reduction of renal perfusion pressure is due to pre- and postglomerular constriction. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2004, 286:R865-R873.
48. Suzuki Y., Matsumura Y., Egi Y., Morimoto S. Effects of Losartan, a nonpeptide angiotensin II receptor antagonist, on norepinephrine overflow and antidiuresis induced by stimulation of renal nerves in anesthetized dogs. J. Pharmacol. Exp. Ther. 1992, 263:956-963.
49. 1 receptors protect the renal afferent arteriole of angiotensin-infused rabbits from norepinephrine-induced oxidative stress. J. Am. Soc. Nephrol. 2006, 17:3347-3354.
50. Wei S.G., Zhang Z.H., Yu Y., Felder R.B. Systemically administered tempol reduces neuronal activity in paraventricular nucleus of hypothalamus and rostral ventrolateral medulla in rats. J. Hypertens. 2009, 27:543-550.
51. 2 receptors in hypertension and ageing. Clin. Exp. Pharmacol. Physiol. 2008, 35:386-390.
52. Wilcox C.S., Pearlman A. Chemistry and antihypertensive effects of tempol and other nitroxides. Pharmacol. Rev. 2008, 60:418-469.
53. Wu B., Fukuo K., Suzuki K., Yoshino G., Kazumi T. Relationships of systemic oxidative stress to body fat distribution, adipokines and inflammatory markers in healthy middle-aged women. Endocr. J. 2009, 56:773-782.
54. Xu H., Fink G.D., Galligan J.J. Nitric oxide-independent effects of tempol on sympathetic nerve activity and blood pressure in DOCA-salt rats. Am. J. Physiol. Heart Circ. Physiol. 2002, 283:H885-H892.
55. - in DOCA-salt rats. Hypertension 2004, 43:329-334.