Disparate roles of AT2 receptors in the renal cortical and medullary circulations of anesthetized rabbits

Hypertension

Volumn 42, Issue 2, 2003, Pages 200-205

  Duke, Lisa M ^a   Eppel, Gabriela A ^a   Widdop, Robert E ^a   Evans, Roger G ^a  

^a NONE

Author keywords

Angiotensin; Kidney; Laser Doppler flowmetry; Rabbits; Receptors; Renal circulation

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANGIOTENSIN III; CANDESARTAN; NICOTINOYLTYROSYL(N BENZYLOXYCARBONYLARGINYL)LYSYLHISTIDYLPROLYLISOLEUCINE; PENTOBARBITAL; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN DERIVATIVE; ANGIOTENSIN RECEPTOR; BENZIMIDAZOLE DERIVATIVE; IMIDAZOLE DERIVATIVE; OLIGOPEPTIDE; PEPTIDE; PYRIDINE DERIVATIVE; TETRAZOLE DERIVATIVE;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; KIDNEY BLOOD FLOW; KIDNEY CIRCULATION; KIDNEY CORTEX; KIDNEY MEDULLA; KIDNEY PERFUSION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; URINARY EXCRETION; VASODILATATION; ANIMAL; BLOOD FLOW; BLOOD PRESSURE; DRUG ANTAGONISM; DRUG POTENTIATION; HEMODYNAMICS; LASER DOPPLER FLOWMETRY; PHYSIOLOGY; RABBIT; VASCULARIZATION; VASOCONSTRICTION;

ANGIOTENSINS; ANIMALS; BENZIMIDAZOLES; BLOOD PRESSURE; HEMODYNAMIC PROCESSES; IMIDAZOLES; KIDNEY CORTEX; KIDNEY MEDULLA; LASER-DOPPLER FLOWMETRY; MALE; OLIGOPEPTIDES; PEPTIDES; PYRIDINES; RABBITS; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN; REGIONAL BLOOD FLOW; RENAL CIRCULATION; TETRAZOLES; VASOCONSTRICTION; VASODILATION;

EID: 0041765636     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000083341.64034.00     Document Type: Article

References (45)

1. Cowley AW Jr. Role of the renal medulla in volume and arterial pressure regulation. Am J Physiol Regul Integr Comp Physiol. 1997;273:R1-R15.
2. Cupples WA, Marsh DJ. Autoregulation of blood flow in renal medulla of the rat: no role for angiotensin II. Can J Physiol Pharmacol. 1988;66:833-836.
3. Evans RG, Madden AC, Denton KM. Diversity of responses of renal cortical and medullary blood flow to vasoconstrictors in conscious rabbits. Acta Physiol Scand. 2000;169:297-308.
4. Huang CL, Davis G, Johns EJ. A study of the action of angiotensin II on perfusion through the cortex and papilla of the rat kidney. Exp Physiol. 1991;76:787-798.
5. Rudenstam J, Creutz J, Gothberg G, Karlstrom G, Bergstrom G. Regional renal haemodynamics of angiotensin II infusion under prostaglandin, kinin or converting enzyme inhibition in the Wistar rat. Blood Press. 2000;9:169-175.
6. Badzynska B, Grzelec-Mojzesowicz M, Dobrowolski L, Sadowski J. Differential effect of angiotensin II on blood circulation in the renal medulla and cortex of anaesthetised rats. J Physiol. 2002;538:159-166.
7. Nobes MS, Harris PJ, Yamada H, Mendelsohn FA. Effects of angiotensin on renal cortical and papillary blood flows measured by laser-Doppler flowmetry. Am J Physiol Renal Physiol. 1991;261:F998-F1006.
8. Walker LL, Rajaratne AA, Blair-West JR, Harris PJ. The effects of angiotensin II on blood perfusion in the rat renal papilla. J Physiol. 1999;519:273-278.
9. Sarkis A, Liu KL, Lo M, Benzoni D. Angiotensin II and renal medullary blood flow in Lyon rats. Am J Physiol Renal Physiol. 2003;284: F365-F372.
10. Rajapakse NW, Oliver JJ, Evans RG. Nitric oxide in responses of regional kidney blood flow to vasoactive agents in anesthetized rabbits. J Cardiovasc Pharmacol. 2002;40:210-219.
11. Oliver JJ, Rajapakse NW, Evans RG. Effects of indomethacin on responses of regional kidney perfusion to vasoactive agents in rabbits. Clin Exp Pharmacol Physiol. 2002;29:873-879.
12. Zou AP, Wu F, Cowley AW Jr. Protective effect of angiotensin II-induced increase in nitric oxide in the renal medullary circulation. Hypertension. 1998;31:271-276.
13. 2 receptor subtypes in the rat kidney. Am J Physiol Renal Physiol. 1999;277:F437-F446.
14. 2 receptor in a renal wrap hypertension model. Hypertension. 1999;33:1237-1242.
15. 1 receptor antagonist in hypertensive rats. Hypertension. 1999;34:1112-1116.
16. Liu KL, Lo M, Grouzmann E, Mutter M, Sassard J. The subtype 2 of angiotensin II receptors and pressure-natriuresis in adult rat kidneys. Br J Pharmacol. 1999;126:826-832.
17. Lo M, Liu KL, Lantelme P, Sassard J. Subtype 2 of angiotensin II receptors controls pressure-natriuresis in rats. J Clin Invest. 1995;95:1394-1397.
18. 2 receptor. Kidney Int. 2000;57:191-202.
19. 2+-signaling. Am J Physiol Heart Circ Physiol. 2003;284: H779-H789.
20. Timmermans PB, Wong PC, Chiu AT, Herblin WF. Nonpeptide angiotensin II receptor antagonists. Trends Pharmacol Sci. 1991;12:55-62.
21. i activation. Circ Res. 2000;87:753-759.
22. de Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T. International union of pharmacology, XXIII: the angiotensin II receptors. Pharmacol Rev. 2000;52:415-472.
23. Souza Dos Santos RA, Passaglio KT, Pesquero JB, Bader M, Simoes ESAC. Interactions between angiotensin(1-7), kinins, and angiotensin II in kidney and blood vessels. Hypertension. 2001;38:660-664.
24. Leonard BL, Malpas SC, Denton KM, Madden AC, Evans RG. Differential control of intrarenal blood flow during reflex increases in sympathetic nerve activity. Am J Physiol Regul Integr Comp Physiol. 2001;280: R62-R68.
25. 1-receptors on regional kidney blood flow and glomerular arteriole diameters. J Hypertens. 2001;19:649-657.
26. Guild SJ, Eppel GA, Malpas SC, Rajapakse NW, Stewart A, Evans RG. Regional responsiveness of renal perfusion to activation of the renal nerves. Am J Physiol Regul Integr Comp Physiol. 2002;283: R1177-R1186.
27. Cundy D, Gurr PA, Knill AM, Tsanaktsidis J. An improved synthesis of (S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)- 4,5,6,7-tetrhydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid, ditrifluoroacetate, dihydrate. (PD123319). Arkivoc. 2000;1:169-175.
28. Ludbrook J. Repeated measurements and multiple comparisons in cardiovascular research. Cardiovasc Res. 1994;28:303-311.
29. Carey RM, Wang ZQ, Siragy HM. Role of the angiotensin type 2 receptor in the regulation of blood pressure and renal function. Hypertension. 2000;35:155-163.
30. 2-dependent signaling in rabbit proximal tubular epithelial cells. Hypertension. 1996;28:663-668.
31. Arima S, Endo Y, Yaoita H, Omata K, Ogawa S, Tsunoda K, Abe M, Takeuchi K, Abe K, Ito S. Possible role of P-450 metabolite of arachidonic acid in vasodilator mechanism of angiotensin II type 2 receptor in the isolated microperfused rabbit afferent arteriole. J Clin Invest. 1997;100:2816-2823.
32. 2 receptor mRNA expression and renal vasodilatation are increased in renal failure. Hypertension. 2001;38:669-673.
33. 1 receptors in the renal papillary effects of acute and chronic nitric oxide inhibition. Am J Physiol Regul Integr Comp Physiol. 1998;274:R760-R766.
34. Ferrario CM, Chappell MC, Dean RH, Iyer SN. Novel angiotensin peptides regulate blood pressure, endothelial function, and natriuresis. J Am Soc Nephrol. 1998;9:1716-1722.
35. 125I]CGP 42112. Brain Res. 1995;677:29-38.
36. Mento PF, Maita ME, Wilkes BM. Renal hemodynamics in rats with myocardial infarction: selective antagonism of angiotensin receptor subtypes. Am J Physiol Heart Circ Physiol. 1996;271:H2306-H2312.
37. 2 receptors in angiotensin II-stimulated contraction of small mesenteric arteries in young SHR. Hypertension. 1999;33:366-372.
38. Thorup C, Kornfeld M, Winaver JM, Goligorsky MS, Moore LC. Angiotensin-II stimulates nitric oxide release in isolated perfused renal resistance arteries. Pflugers Arch. 1998;435:432-434.
39. Pallone TL, Silldorff EP, Zhang Z. Inhibition of calcium signaling in descending vasa recta endothelia by ANG II. Am J Physiol Heart Circ Physiol. 2000;278:H1248-H1255.
40. Dickhout JG, Mori T, Cowley AW Jr. Tubulovascular nitric oxide crosstalk: buffering of angiotensin II-induced medullary vasoconstriction. Circ Res. 2002;91:487-493.
41. Carey RM, Howell NL, Jin XH, Siragy HM. Angiotensin type 2 receptor-mediated hypotension in angiotensin type-1 receptor-blocked rats. Hypertension. 2001;38:1272-1277.
42. 1 agonist [Phe2, Ile3, Orn8]] vasopressin on regional kidney perfusion and renal excretory function in anesthetized rabbits. J Cardiovasc Pharmacol. 1998;32:571-581.
43. Navar LG, Harrison-Bernard LM, Nishiyama A, Kobori H. Regulation of intrarenal angiotensin II in hypertension. Hypertension. 2002;39:316-322.
44. Parekh N. A novel method for infusing drugs continuously into the renal artery of rats. Am J Physiol Renal Physiol. 1995;268:F967-F971.
45. Eppel GA, Bergstrom G, Anderson WP, Evans RG. Autoregulation of renal medullary blood flow in rabbits. Am J Physiol Regul Integr Comp Physiol. 2003;284:R233-R244.