Isoobtusilactone A sensitizes human hepatoma Hep G2 cells to TRAIL-induced apoptosis via ROS and CHOP-mediated up-regulation of DR5

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 13, 2012, Pages 3533-3539

  Chen, Chung Yi ^a   Yiin, Shuenn Jiun ^b   Hsu, Jue Liang ^c   Wang, Wei Che ^a   Lin, Shan Chun ^a   Chern, Chi Liang ^a  

^a FOOYIN UNIVERSITY   (Taiwan)

^b TAJEN UNIVERSITY   (Taiwan)

^c NATIONAL PINGTUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

apoptosis; CHOP; DR5; IOA; reactive oxygen species; TRAIL

Indexed keywords

CHOP; DR5; IOA; REACTIVE OXYGEN SPECIES; TRAIL;

AMINO ACIDS; GENETIC ENGINEERING; OXYGEN; RNA; TUMORS;

CELL DEATH;

ALKANE; DDIT3 PROTEIN, HUMAN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; ISOOBTUSILACTONE A; LACTONE; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR;

APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; CHEMISTRY; CINNAMOMUM; DRUG EFFECT; GENETICS; HUMAN; LIVER TUMOR; METABOLISM; PATHOPHYSIOLOGY; UPREGULATION;

ALKANES; APOPTOSIS; CINNAMOMUM; HEP G2 CELLS; HUMANS; LACTONES; LIVER NEOPLASMS; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSCRIPTION FACTOR CHOP; UP-REGULATION;

CINNAMOMUM KOTOENSE;

EID: 84859385962     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf2051224     Document Type: Article

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