Synthesis of aminopyridines and aminopyridones by cobalt-catalyzed [2+2+2] cycloadditions involving yne-ynamides: Scope, limitations, and mechanistic insights

Chemistry - A European Journal

Volumn 18, Issue 14, 2012, Pages 4337-4344

  Garcia, Pierre ^a   Evanno, Yannick ^b   George, Pascal ^b   Sevrin, Mireille ^b   Ricci, Gino ^b   Malacria, Max ^a   Aubert, Corinne ^a   Gandon, Vincent ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b SANOFI   (France)

Author keywords

alkynes; cobalt; cycloaddition; nitrogen heterocycles; reaction mechanisms; reactive intermediates

Indexed keywords

[2+2+2] CYCLOADDITION; ALKYNES; AMINOPYRIDINES; COBALTACYCLOPENTADIENE; CYCLOADDITIONS; DFT COMPUTATIONS; DIMETHYL FUMARATE; ELECTRON-DEFICIENT; IN-DEPTH STUDY; NITROGEN HETEROCYCLES; PRECATALYSTS; REACTION MECHANISM; REACTIVE INTERMEDIATE; SUBSTITUTION PATTERNS; SYNTHETIC METHODOLOGY;

ACETYLENE; AMINES; CATALYSIS; COBALT; CYANIDES; ELECTRONIC PROPERTIES; PYRIDINE;

CYCLOADDITION;

ALKYNE; AMIDE; AMINOPYRIDINE DERIVATIVE; COBALT; NITRILE; PYRIDONE DERIVATIVE;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; STEREOISOMERISM; SYNTHESIS;

ALKYNES; AMIDES; AMINOPYRIDINES; CATALYSIS; COBALT; CYCLIZATION; MOLECULAR STRUCTURE; NITRILES; PYRIDONES; STEREOISOMERISM;

EID: 84859371583     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201103906     Document Type: Article

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