Application of an enantioselective LC-ESI MS/MS procedure to determine R- and S-hyoscyamine following intravenous atropine administration in swine

Drug Testing and Analysis

Volumn 4, Issue 3-4, 2012, Pages 194-198

  John, Harald ^a   Mikler, John ^b   Worek, Franz ^a   Thiermann, Horst ^a  

^a BUNDESWEHR INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (Germany)

^b DEFENCE RESEARCH AND DEVELOPMENT CANADA   (Canada)

Author keywords

Atropine; Enantiomers; LC ESI MS MS; S and R hyoscyamine; Swine

Indexed keywords

BODY FLUIDS; HYDROLYSIS; STEREOSELECTIVITY; SULFUR COMPOUNDS;

ATROPINE; ENANTIOSELECTIVE; HUMAN SERUM; LC MS/MS(ESI); LC-ESI-MS/MS; LC/ESI-MS/MS; MUSCARINIC RECEPTOR; S- AND R- HYOSCYAMINE; STEREO-SELECTIVE; SWINE;

ENANTIOMERS;

ATROPINE; HYOSCYAMINE; PESTICIDE;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; ENANTIOMER; ENANTIOSELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDROLYSIS; LIQUID CHROMATOGRAPHY; MALE; MASS FRAGMENTOGRAPHY; METABOLISM; NONHUMAN; PLASMA; PRECIPITATION; PRIORITY JOURNAL; RABBIT; STEREOCHEMISTRY; SUPERNATANT; SWINE;

EID: 84859334845     PISSN: 19427603     EISSN: 19427611     Source Type: Journal    
DOI: 10.1002/dta.338     Document Type: Article

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