TRAF6 promotes myogenic differentiation via the TAK1/p38 mitogen-activated protein kinase and akt pathways

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Xiao, Fang ^a   Wang, Haixia ^a   Fu, Xinrong ^a   Li, Yanfeng ^a   Wu, Zhenguo ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UBIQUITIN PROTEIN LIGASE E3; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; LUCIFERASE; MAP KINASE KINASE KINASE 7; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; ENZYME ACTIVATION; ENZYME ACTIVITY; IN VIVO STUDY; MACROPHAGE MIGRATION; MOUSE; MUSCLE DEVELOPMENT; MUSCLE DISEASE; MUSCLE INJURY; MUSCLE REGENERATION; MYOBLAST; NONHUMAN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DRUG ANTAGONISM; GENETICS; METABOLISM; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELLS, CULTURED; GREEN FLUORESCENT PROTEINS; LUCIFERASES; MAP KINASE KINASE KINASES; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; MYOBLASTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; REGENERATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6;

EID: 84859316005     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034081     Document Type: Article

References (48)

1. Buckingham M, (2001) Skeletal muscle formation in vertebrates. Curr Opin Genet Dev 11: 440-448.
2. Puri PL, Sartorelli V, (2000) Regulation of muscle regulatory factors by DNA-binding, interacting proteins, and post-transcriptional modifications. J Cell Physiol 185: 155-173.
3. Sabourin LA, Rudnicki MA, (2000) The molecular regulation of myogenesis. Clin Genet 57: 16-25.
4. Berkes CA, Tapscott SJ, (2005) MyoD and the transcriptional control of myogenesis. Semin Cell Dev Biol 16: 585-595.
5. Molkentin JD, Olson EN, (1996) Defining the regulatory networks for muscle development. Curr Opin Genet Dev 6: 445-453.
6. Potthoff MJ, Olson EN, (2007) MEF2: a central regulator of diverse developmental programs. Development 134: 4131-4140.
7. Black BL, Olson EN, (1998) Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Annu Rev Cell Dev Biol 14: 167-196.
8. Florini JR, Ewton DZ, Coolican SA, (1996) Growth hormone and the insulin-like growth factor system in myogenesis. Endocr Rev 17: 481-517.
9. Jiang BH, Aoki M, Zheng JZ, Li J, Vogt PK, (1999) Myogenic signaling of phosphatidylinositol 3-kinase requires the serine-threonine kinase Akt/protein kinase B. Proc Natl Acad Sci U S A 96: 2077-2081.
10. Tamir Y, Bengal E, (2000) Phosphoinositide 3-kinase induces the transcriptional activity of MEF2 proteins during muscle differentiation. J Biol Chem 275: 34424-34432.
11. Xu Q, Wu Z, (2000) The insulin-like growth factor-phosphatidylinositol 3-kinase-Akt signaling pathway regulates myogenin expression in normal myogenic cells but not in rhabdomyosarcoma-derived RD cells. J Biol Chem 275: 36750-36757.
12. Bois PR, Grosveld GC, (2003) FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts. Embo J 22: 1147-1157.
13. Hribal ML, Nakae J, Kitamura T, Shutter JR, Accili D, (2003) Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors. J Cell Biol 162: 535-541.
14. Keren A, Tamir Y, Bengal E, (2006) The p38 MAPK signaling pathway: a major regulator of skeletal muscle development. Mol Cell Endocrinol 252: 224-230.
15. Lluis F, Perdiguero E, Nebreda AR, Munoz-Canoves P, (2006) Regulation of skeletal muscle gene expression by p38 MAP kinases. Trends Cell Biol 16: 36-44.
16. Rampalli S, Li L, Mak E, Ge K, Brand M, et al. (2007) p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation. Nat Struct Mol Biol 14: 1150-1156.
17. Wu Z, Woodring PJ, Bhakta KS, Tamura K, Wen F, et al. (2000) p38 and Extracellular Signal-Regulated Kinases Regulate the Myogenic Program at Multiple Steps. Mol Cell Biol 20: 3951-3964.
18. Zetser A, Gredinger E, Bengal E, (1999) p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factor. J Biol Chem 274: 5193-5200.
19. Lluis F, Ballestar E, Suelves M, Esteller M, Munoz-Canoves P, (2005) E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription. Embo J 24: 974-984.
20. Simone C, Forcales SV, Hill DA, Imbalzano AN, Latella L, et al. (2004) p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci. Nat Genet 36: 738-743.
21. Perdiguero E, Ruiz-Bonilla V, Gresh L, Hui L, Ballestar E, et al. (2007) Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation. Embo J 26: 1245-1256.
22. Wang H, Xu Q, Xiao F, Jiang Y, Wu Z, (2008) Involvement of the p38 mitogen-activated protein kinase alpha, beta, and gamma isoforms in myogenic differentiation. Mol Biol Cell 19: 1519-1528.
23. Cabane C, Englaro W, Yeow K, Ragno M, Derijard B, (2003) Regulation of C2C12 myogenic terminal differentiation by MKK3/p38alpha pathway. Am J Physiol Cell Physiol 284: C658-666.
24. Bhatnagar S, Kumar A, Makonchuk DY, Li H, Kumar A, (2011) Transforming growth factor-beta-activated kinase 1 is an essential regulator of myogenic differentiation. J Biol Chem 285: 6401-6411.
25. Adhikari A, Xu M, Chen ZJ, (2007) Ubiquitin-mediated activation of TAK1 and IKK. Oncogene 26: 3214-3226.
26. Landstrom M, (2010) The TAK1-TRAF6 signalling pathway. Int J Biochem Cell Biol 42: 585-589.
27. Takeuchi O, Akira S, (2010) Pattern recognition receptors and inflammation. Cell 140: 805-820.
28. Chung JY, Park YC, Ye H, Wu H, (2002) All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction. J Cell Sci 115: 679-688.
29. Liu S, Chen ZJ, (2011) Expanding role of ubiquitination in NF-kappaB signaling. Cell Res 21: 6-21.
30. Xia ZP, Sun L, Chen X, Pineda G, Jiang X, et al. (2009) Direct activation of protein kinases by unanchored polyubiquitin chains. Nature 461: 114-119.
31. Kanayama A, Seth RB, Sun L, Ea CK, Hong M, et al. (2004) TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains. Mol Cell 15: 535-548.
32. Yang WL, Wang J, Chan CH, Lee SW, Campos AD, et al. (2009) The E3 ligase TRAF6 regulates Akt ubiquitination and activation. Science 325: 1134-1138.
33. Paul PK, Gupta SK, Bhatnagar S, Panguluri SK, Darnay BG, et al. (2010) Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice. J Cell Biol 191: 1395-1411.
34. Charge SB, Rudnicki MA, (2004) Cellular and molecular regulation of muscle regeneration. Physiol Rev 84: 209-238.
35. Deng L, Wang C, Spencer E, Yang L, Braun A, et al. (2000) Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 103: 351-361.
36. Blank JL, Gerwins P, Elliott EM, Sather S, Johnson GL, (1996) Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase. J Biol Chem 271: 5361-5368.
37. Yamaguchi K, Shirakabe K, Shibuya H, Irie K, Oishi I, et al. (1995) Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. Science 270: 2008-2011.
38. Singhirunnusorn P, Suzuki S, Kawasaki N, Saiki I, Sakurai H, (2005) Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2. J Biol Chem 280: 7359-7368.
39. Ninomiya-Tsuji J, Kishimoto K, Hiyama A, Inoue J, Cao Z, et al. (1999) The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 398: 252-256.
40. Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, et al. (1996) Mechanism of activation of protein kinase B by insulin and IGF-1. Embo J 15: 6541-6551.
41. Arnold L, Henry A, Poron F, Baba-Amer Y, van Rooijen N, et al. (2007) Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis. J Exp Med 204: 1057-1069.
42. Mueck T, Berger F, Buechsler I, Valchanova RS, Landuzzi L, et al. (2011) TRAF6 regulates proliferation and differentiation of skeletal myoblasts. Differentiation 81: 99-106.
43. Lu M, Krauss RS, (2010) N-cadherin ligation, but not Sonic hedgehog binding, initiates Cdo-dependent p38alpha/beta MAPK signaling in skeletal myoblasts. Proc Natl Acad Sci U S A 107: 4212-4217.
44. Kang JS, Bae GU, Yi MJ, Yang YJ, Oh JE, et al. (2008) A Cdo-Bnip-2-Cdc42 signaling pathway regulates p38alpha/beta MAPK activity and myogenic differentiation. J Cell Biol 182: 497-507.
45. Takaesu G, Kang JS, Bae GU, Yi MJ, Lee CM, et al. (2006) Activation of p38alpha/beta MAPK in myogenesis via binding of the scaffold protein JLP to the cell surface protein Cdo. J Cell Biol 175: 383-388.
46. Palacios D, Mozzetta C, Consalvi S, Caretti G, Saccone V, et al. (2010) TNF/p38alpha/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration. Cell Stem Cell 7: 455-469.
47. Wan J, Sun L, Mendoza JW, Chui YL, Huang DP, et al. (2004) Elucidation of the c-Jun N-terminal kinase pathway mediated by Estein-Barr virus-encoded latent membrane protein 1. Mol Cell Biol 24: 192-199.
48. Xu Q, Yu L, Liu L, Cheung CF, Li X, et al. (2002) p38 Mitogen-activated Protein Kinase-, Calcium-Calmodulin-dependent Protein Kinase-, and Calcineurin-mediated Signaling Pathways Transcriptionally Regulate Myogenin Expression. Mol Biol Cell 13: 1940-1952.