-
1
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano, M., Bell, D.W., Haber, D.A. & Li, E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247-257 (1999).
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
2
-
-
0029929142
-
DNA methyltransferase in normal and Dnmtn/Dnmtn mouse embryos
-
Trasler, J.M., Trasler, D.G., Bestor, T.H., Li, E. & Ghibu, F. DNA methyltransferase in normal and Dnmtn/Dnmtn mouse embryos. Dev. Dyn. 206, 239-247 (1996).
-
(1996)
Dev. Dyn.
, vol.206
, pp. 239-247
-
-
Trasler, J.M.1
Trasler, D.G.2
Bestor, T.H.3
Li, E.4
Ghibu, F.5
-
3
-
-
0032480226
-
DNA hypomethylation leads to elevated mutation rates
-
Chen, R.Z., Pettersson, U., Beard, C., Jackson-Grusby, L. & Jaenisch, R. DNA hypomethylation leads to elevated mutation rates. Nature 395, 89-93 (1998).
-
(1998)
Nature
, vol.395
, pp. 89-93
-
-
Chen, R.Z.1
Pettersson, U.2
Beard, C.3
Jackson-Grusby, L.4
Jaenisch, R.5
-
4
-
-
0023848337
-
Immunodeficiency, centromeric heterochromatin instability of chromosomes 1, 9, and 16, and facial anomalies: The ICF syndrome
-
Maraschio, P., Zuffardi, O., Dalla Fior, T. & Tiepolo, L. Immunodeficiency, centromeric heterochromatin instability of chromosomes 1, 9, and 16, and facial anomalies: the ICF syndrome. J. Med. Genet. 25, 173-180 (1988).
-
(1988)
J. Med. Genet.
, vol.25
, pp. 173-180
-
-
Maraschio, P.1
Zuffardi, O.2
Dalla Fior, T.3
Tiepolo, L.4
-
5
-
-
0033435205
-
The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome
-
Hansen, R.S. et al. The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome. Proc. Natl. Acad. Sci. USA 96, 14412-14417 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14412-14417
-
-
Hansen, R.S.1
-
6
-
-
0033547330
-
Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
-
Xu, G.L. et al. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature 402, 187-191 (1999).
-
(1999)
Nature
, vol.402
, pp. 187-191
-
-
Xu, G.L.1
-
7
-
-
0020480862
-
Asymmetrical distribution of CpG in an 'average' mammalian gene
-
McClelland, M, & Ivarie, R. Asymmetrical distribution of CpG in an 'average' mammalian gene. Nucleic Acids Res. 10, 7865-7877 (1982).
-
(1982)
Nucleic Acids Res.
, vol.10
, pp. 7865-7877
-
-
McClelland, M.1
Ivarie, R.2
-
8
-
-
0022000776
-
A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA
-
Bird, A., Taggart, M., Frommer, M., Miller, O.J. & Macleod, D. A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA. Cell 40, 91-99 (1985).
-
(1985)
Cell
, vol.40
, pp. 91-99
-
-
Bird, A.1
Taggart, M.2
Frommer, M.3
Miller, O.J.4
Macleod, D.5
-
9
-
-
0023216891
-
CpG islands in vertebrate genomes
-
Gardiner-Garden, M. & Frommer, M. CpG islands in vertebrate genomes. J. Mol. Biol. 196, 261-282 (1987).
-
(1987)
J. Mol. Biol.
, vol.196
, pp. 261-282
-
-
Gardiner-Garden, M.1
Frommer, M.2
-
10
-
-
0026742792
-
CpG islands as gene markers in the human genome
-
Larsen, F., Gundersen, G., Lopez, R. & Prydz, H. CpG islands as gene markers in the human genome. Genomics 13, 1095-1107 (1992).
-
(1992)
Genomics
, vol.13
, pp. 1095-1107
-
-
Larsen, F.1
Gundersen, G.2
Lopez, R.3
Prydz, H.4
-
11
-
-
0037133565
-
Comprehensive analysis of CpG islands in human chromosomes 21 and 22
-
Takai, D. & Jones, P.A. Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc. Natl. Acad. Sci. USA 99, 3740-3745 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3740-3745
-
-
Takai, D.1
Jones, P.A.2
-
12
-
-
0032076565
-
Imprinting and the initiation of gene silencing in the germ line
-
Surani, M.A. Imprinting and the initiation of gene silencing in the germ line. Cell 93, 309-312 (1998).
-
(1998)
Cell
, vol.93
, pp. 309-312
-
-
Surani, M.A.1
-
13
-
-
0027016577
-
Mammalian X chromosome inactivation
-
Gartler, S.M., Dyer, K.A. & Goldman, M.A. Mammalian X chromosome inactivation. Mol. Genet. Med. 2, 121-160 (1992).
-
(1992)
Mol. Genet. Med.
, vol.2
, pp. 121-160
-
-
Gartler, S.M.1
Dyer, K.A.2
Goldman, M.A.3
-
14
-
-
0037413703
-
Methylation of HoxAS and HoxBS and its relevance to expression during mouse development
-
Hershko, A.Y., Kafri, T., Fainsod, A. & Razin, A. Methylation of HoxAS and HoxBS and its relevance to expression during mouse development. Gene 302, 65-72 (2003).
-
(2003)
Gene
, vol.302
, pp. 65-72
-
-
Hershko, A.Y.1
Kafri, T.2
Fainsod, A.3
Razin, A.4
-
15
-
-
14744267496
-
Association of tissue-specific differentially methylated regions (TDMs) with differential gene expression
-
Song, F et al. Association of tissue-specific differentially methylated regions (TDMs) with differential gene expression. Proc. Natl. Acad. Sci. USA 102, 3336-3341 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 3336-3341
-
-
Song, F.1
-
16
-
-
20044390368
-
DNA methylation profiling of the human major histocompatibility complex: A pilot study for the human epigenome project
-
Rakyan, V.K. et al. DNA methylation profiling of the human major histocompatibility complex: a pilot study for the human epigenome project. PLoS Biol. 2, e405 (2004).
-
(2004)
PLoS Biol.
, vol.2
-
-
Rakyan, V.K.1
-
17
-
-
0032694084
-
DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter
-
De Smet, C., Lurquin, C., Lethe, B., Martelange, B. & Boon, T. DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter. Mol. Cell. Biol. 19, 7327-7335 (1999).
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7327-7335
-
-
De Smet, C.1
Lurquin, C.2
Lethe, B.3
Martelange, B.4
Boon, T.5
-
18
-
-
0036613432
-
Role for DNA methylation in the control of cell type-specific maspin expression
-
Futscher, B.W. et al. Role for DNA methylation in the control of cell type-specific maspin expression. Nat. Genet. 31, 175-179 (2002).
-
(2002)
Nat. Genet.
, vol.31
, pp. 175-179
-
-
Futscher, B.W.1
-
19
-
-
0035895505
-
The sequence of the human genome
-
Venter, J.C. et al. The sequence of the human genome. Science 291, 1304-1351 1289 (2001).
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
-
20
-
-
0027141519
-
Number of CpG islands and genes in human and mouse
-
Antequera, F. & Bird, A. Number of CpG islands and genes in human and mouse. Proc. Natl. Acad. Sci. USA 90, 11995-11999 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11995-11999
-
-
Antequera, F.1
Bird, A.2
-
21
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander, E.S. et al. Initial sequencing and analysis of the human genome. Nature 409, 860-921 (2001).
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
-
22
-
-
17344371740
-
High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays
-
Pinkel, D. et al. High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nat. Genet. 20, 207-211 (1998).
-
(1998)
Nat. Genet.
, vol.20
, pp. 207-211
-
-
Pinkel, D.1
-
23
-
-
0034129516
-
Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene
-
Albertson, D.G. et al. Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene. Nat. Genet. 25, 144-146 (2000).
-
(2000)
Nat. Genet.
, vol.25
, pp. 144-146
-
-
Albertson, D.G.1
-
24
-
-
18344392245
-
Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas
-
Hodgson, G. et al. Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas. Nat. Genet. 29, 459-464 (2001).
-
(2001)
Nat. Genet.
, vol.29
, pp. 459-464
-
-
Hodgson, G.1
-
25
-
-
0035179871
-
Assembly of microarrays for genome-wide measurement of DNA copy number
-
Snijders, A.M. et al. Assembly of microarrays for genome-wide measurement of DNA copy number. Nat. Genet. 29, 263-264 (2001).
-
(2001)
Nat. Genet.
, vol.29
, pp. 263-264
-
-
Snijders, A.M.1
-
26
-
-
20044371978
-
Mapping segmental and sequence variations among laboratory mice using BAC array CGH
-
Snijders, A.M. et al. Mapping segmental and sequence variations among laboratory mice using BAC array CGH. Genome Res. 15, 302-311 (2005).
-
(2005)
Genome Res.
, vol.15
, pp. 302-311
-
-
Snijders, A.M.1
-
27
-
-
10744233914
-
A tiling resolution DNA microarray with complete coverage of the human genome
-
Ishkanian, A.S. et al. A tiling resolution DNA microarray with complete coverage of the human genome. Nat. Genet. 36, 299-303 (2004).
-
(2004)
Nat. Genet.
, vol.36
, pp. 299-303
-
-
Ishkanian, A.S.1
-
28
-
-
0023181267
-
Use of restriction enzymes to detect potential gene sequences in mammalian DNA
-
Lindsay, S, & Bird, A.P. Use of restriction enzymes to detect potential gene sequences in mammalian DNA. Nature 327, 336-338 (1987).
-
(1987)
Nature
, vol.327
, pp. 336-338
-
-
Lindsay, S.1
Bird, A.P.2
-
29
-
-
0343621494
-
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
-
Costello, J.F. et al. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat. Genet. 24, 132-138 (2000).
-
(2000)
Nat. Genet.
, vol.24
, pp. 132-138
-
-
Costello, J.F.1
-
30
-
-
1542620777
-
Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family
-
Qualmann, B., Boeckers, T.M., Jeromin, M., Gundelfinger, E.D. & Kessels, M.M. Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family. J. Neurosci. 24, 2481-2495 (2004).
-
(2004)
J. Neurosci.
, vol.24
, pp. 2481-2495
-
-
Qualmann, B.1
Boeckers, T.M.2
Jeromin, M.3
Gundelfinger, E.D.4
Kessels, M.M.5
-
31
-
-
0042828948
-
Molecular characterisation of the 22q13 deletion syndrome supports the role of haploinsufficiency of SHANK3/PROSAP2 in the major neurological symptoms
-
Wilson, H.L. et al. Molecular characterisation of the 22q13 deletion syndrome supports the role of haploinsufficiency of SHANK3/PROSAP2 in the major neurological symptoms. J. Med. Genet. 40, 575-584 (2003).
-
(2003)
J. Med. Genet.
, vol.40
, pp. 575-584
-
-
Wilson, H.L.1
-
32
-
-
0022362663
-
A familial pericentric inversion of chromosome 22 with a recombinant subject illustrating a 'pure' partial monosomy syndrome
-
Watt, J.L. et al. A familial pericentric inversion of chromosome 22 with a recombinant subject illustrating a 'pure' partial monosomy syndrome. J. Med. Genet. 22, 283-287 (1985).
-
(1985)
J. Med. Genet.
, vol.22
, pp. 283-287
-
-
Watt, J.L.1
-
33
-
-
0035877009
-
22q13 deletion syndrome
-
Phelan, M.C. et al. 22q13 deletion syndrome. Am. J. Med. Genet. 101, 91-99 (2001).
-
(2001)
Am. J. Med. Genet.
, vol.101
, pp. 91-99
-
-
Phelan, M.C.1
-
34
-
-
0034927366
-
Disruption of the ProSAP2 gene in a t(12;22)(q24.1;q13.3) is associated with the 22q13.3 deletion syndrome
-
Bonaglia, M.C. et al. Disruption of the ProSAP2 gene in a t(12;22)(q24.1;q13.3) is associated with the 22q13.3 deletion syndrome. Am. J. Hum. Genet. 69, 261-268 (2001).
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 261-268
-
-
Bonaglia, M.C.1
-
35
-
-
3342927934
-
Role of transposable elements in heterochromatin and epigenetic control
-
Lippman, Z. et al. Role of transposable elements in heterochromatin and epigenetic control. Nature 430, 471-476 (2004).
-
(2004)
Nature
, vol.430
, pp. 471-476
-
-
Lippman, Z.1
-
36
-
-
0030888263
-
Identification of DNA methylation markers for human breast carcinomas using the methylation-sensitive restriction fingerprinting technique
-
Huang, T.H. et al. Identification of DNA methylation markers for human breast carcinomas using the methylation-sensitive restriction fingerprinting technique. Cancer Res. 57, 1030-1034 (1997).
-
(1997)
Cancer Res.
, vol.57
, pp. 1030-1034
-
-
Huang, T.H.1
-
37
-
-
19944430797
-
Genomic maps and comparative analysis of histone modifications in human and mouse
-
Bernstein, B.E. et al. Genomic maps and comparative analysis of histone modifications in human and mouse. Cell 120, 169-181 (2005).
-
(2005)
Cell
, vol.120
, pp. 169-181
-
-
Bernstein, B.E.1
-
38
-
-
0020489781
-
Amount and distribution of 5-methylcytosine in human DNA from different types of tissues and cells
-
Ehrlich, M. et al. Amount and distribution of 5-methylcytosine in human DNA from different types of tissues and cells. Nucleic Acids Res. 10, 2709-2721 (1982).
-
(1982)
Nucleic Acids Res.
, vol.10
, pp. 2709-2721
-
-
Ehrlich, M.1
-
39
-
-
7544231794
-
Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells
-
Lorincz, M.C., Dickerson, D.R., Schmitt, M. & Groudine, M. Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells. Nat. Struct. Mol. Biol. 11, 1068-1075 (2004).
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 1068-1075
-
-
Lorincz, M.C.1
Dickerson, D.R.2
Schmitt, M.3
Groudine, M.4
-
40
-
-
0029957792
-
The activation of human gene Mage-1 in tumor cells is correlated with genome-wide demethylation
-
Desmet, C. et al. The activation of human gene Mage-1 in tumor cells is correlated with genome-wide demethylation. Proc. Natl. Acad. Sci. USA 93, 7149-7153 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7149-7153
-
-
Desmet, C.1
-
41
-
-
0036180003
-
Fully automatic quantification of microarray image data
-
Jain, A.J. et al. Fully automatic quantification of microarray image data. Genome Res. 12, 325-332 (2002).
-
(2002)
Genome Res.
, vol.12
, pp. 325-332
-
-
Jain, A.J.1
-
42
-
-
0030305457
-
A language for data analysis and graphics
-
Ihaka, R. & Gentleman, R. A language for data analysis and graphics. J. Comput. Graph. Stat. 5, 299-314 (1996).
-
(1996)
J. Comput. Graph. Stat.
, vol.5
, pp. 299-314
-
-
Ihaka, R.1
Gentleman, R.2
-
43
-
-
0035407651
-
Bisulfite genomic sequencing: Systematic investigation of critical experimental parameters
-
Grunau, C., Clark, S.J. & Rosenthal, A. Bisulfite genomic sequencing: systematic investigation of critical experimental parameters. Nucleic Acids Res. 29, e65 (2001).
-
(2001)
Nucleic Acids Res.
, vol.29
-
-
Grunau, C.1
Clark, S.J.2
Rosenthal, A.3
|