-
1
-
-
77949329050
-
Tumor microenvironments direct the recruitment and expansion of human Th17 cells
-
Su X, Ye J, Hsueh EC, Zhang Y, Hoft DF, Peng G. Tumor microenvironments direct the recruitment and expansion of human Th17 cells. J Immunol 2010; 184:1630-41.
-
(2010)
J Immunol
, vol.184
, pp. 1630-1641
-
-
Su, X.1
Ye, J.2
Hsueh, E.C.3
Zhang, Y.4
Hoft, D.F.5
Peng, G.6
-
2
-
-
80054121352
-
Th17 and Th17-stimulated CD8(+) T cells play a distinct role in Th17-induced preventive and therapeutic antitumor immunity
-
Ankathatti MM, Deng Y, Mulligan SH etal. Th17 and Th17-stimulated CD8(+) T cells play a distinct role in Th17-induced preventive and therapeutic antitumor immunity. Cancer Immunol Immunother 2011; 60:1473-84.
-
(2011)
Cancer Immunol Immunother
, vol.60
, pp. 1473-1484
-
-
Ankathatti, M.M.1
Deng, Y.2
Mulligan, S.H.3
-
3
-
-
77958122532
-
Induction of Th17 cells in the tumor microenvironment improves survival in a murine model of pancreatic cancer
-
Gnerlich JL, Mitchem JB, Weir JS etal. Induction of Th17 cells in the tumor microenvironment improves survival in a murine model of pancreatic cancer. J Immunol 2010; 185:4063-71.
-
(2010)
J Immunol
, vol.185
, pp. 4063-4071
-
-
Gnerlich, J.L.1
Mitchem, J.B.2
Weir, J.S.3
-
4
-
-
70449530422
-
T helper 17 cells promote cytotoxic T cell activation in tumor immunity
-
Martin-Orozco N, Muranski P, Chung Y etal. T helper 17 cells promote cytotoxic T cell activation in tumor immunity. Immunity 2009; 31:787-98.
-
(2009)
Immunity
, vol.31
, pp. 787-798
-
-
Martin-Orozco, N.1
Muranski, P.2
Chung, Y.3
-
5
-
-
47649122633
-
Tumor-specific Th17-polarized cells eradicate large established melanoma
-
Muranski P, Boni A, Antony PA etal. Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood 2008; 112:362-73.
-
(2008)
Blood
, vol.112
, pp. 362-373
-
-
Muranski, P.1
Boni, A.2
Antony, P.A.3
-
6
-
-
67650495415
-
IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
-
Wang L, Yi T, Kortylewski M etal. IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med 2009; 206:1457-64.
-
(2009)
J Exp Med
, vol.206
, pp. 1457-1464
-
-
Wang, L.1
Yi, T.2
Kortylewski, M.3
-
7
-
-
79953681584
-
IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma
-
Liu J, Duan Y, Cheng X etal. IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma. Biochem Biophys Res Commun 2011; 407:348-54.
-
(2011)
Biochem Biophys Res Commun
, vol.407
, pp. 348-354
-
-
Liu, J.1
Duan, Y.2
Cheng, X.3
-
8
-
-
79953065052
-
Tumor-infiltrating CD4+ Th17 cells produce IL-17 in tumor microenvironment and promote tumor progression in human gastric cancer
-
Iida T, Iwahashi M, Katsuda M etal. Tumor-infiltrating CD4+ Th17 cells produce IL-17 in tumor microenvironment and promote tumor progression in human gastric cancer. Oncol Rep 2011; 25:1271-7.
-
(2011)
Oncol Rep
, vol.25
, pp. 1271-1277
-
-
Iida, T.1
Iwahashi, M.2
Katsuda, M.3
-
9
-
-
77953702039
-
The role of T-helper 17 (Th17) cells in patients with medulloblastoma
-
Zhou P, Sha H, Zhu J. The role of T-helper 17 (Th17) cells in patients with medulloblastoma. J Int Med Res 2010; 38:611-19.
-
(2010)
J Int Med Res
, vol.38
, pp. 611-619
-
-
Zhou, P.1
Sha, H.2
Zhu, J.3
-
10
-
-
64549108462
-
Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients
-
Zhang JP, Yan J, Xu J etal. Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients. J Hepatol 2009; 50:980-9.
-
(2009)
J Hepatol
, vol.50
, pp. 980-989
-
-
Zhang, J.P.1
Yan, J.2
Xu, J.3
-
11
-
-
17444401702
-
Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice
-
Tartour E, Fossiez I, Joyeux A etal. Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice. Cancer Res 1999; 59:3698-704.
-
(1999)
Cancer Res
, vol.59
, pp. 3698-3704
-
-
Tartour, E.1
Fossiez, I.2
Joyeux, A.3
-
12
-
-
27144449330
-
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis
-
Numasaki M, Watanabe M, Suzuki T etal. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J Immunol 2005; 175:6177-89.
-
(2005)
J Immunol
, vol.175
, pp. 6177-6189
-
-
Numasaki, M.1
Watanabe, M.2
Suzuki, T.3
-
13
-
-
0034613201
-
Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R
-
Xie MH, Aggarwal S, Ho WH etal. Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J Biol Chem 2000; 275:31335-9.
-
(2000)
J Biol Chem
, vol.275
, pp. 31335-31339
-
-
Xie, M.H.1
Aggarwal, S.2
Ho, W.H.3
-
14
-
-
0035951795
-
Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes
-
Kotenko SV, Izotova LS, Mirochnitchenko OV etal. Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes. J Biol Chem 2001; 276:2725-32.
-
(2001)
J Biol Chem
, vol.276
, pp. 2725-2732
-
-
Kotenko, S.V.1
Izotova, L.S.2
Mirochnitchenko, O.V.3
-
15
-
-
2342462460
-
Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation
-
Radaeva S, Sun R, Pan HN etal. Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation. Hepatology 2004; 39:1332-42.
-
(2004)
Hepatology
, vol.39
, pp. 1332-1342
-
-
Radaeva, S.1
Sun, R.2
Pan, H.N.3
-
16
-
-
77958489808
-
Functional biology of the IL-22-IL-22R pathway in regulating immunity and inflammation at barrier surfaces
-
Sonnenberg GF, Fouser LA, Artis D. Functional biology of the IL-22-IL-22R pathway in regulating immunity and inflammation at barrier surfaces. Adv Immunol 2010; 107:1-29.
-
(2010)
Adv Immunol
, vol.107
, pp. 1-29
-
-
Sonnenberg, G.F.1
Fouser, L.A.2
Artis, D.3
-
17
-
-
2142717328
-
Interleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells
-
Nagalakshmi ML, Rascle A, Zurawski S etal. Interleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells. Int Immunopharmacol 2004; 4:679-91.
-
(2004)
Int Immunopharmacol
, vol.4
, pp. 679-691
-
-
Nagalakshmi, M.L.1
Rascle, A.2
Zurawski, S.3
-
18
-
-
79952217505
-
Protective properties of inhaled IL-22 in a model of ventilator-induced lung injury
-
Hoegl S, Bachmann M, Scheiermann P etal. Protective properties of inhaled IL-22 in a model of ventilator-induced lung injury. Am J Respir Cell Mol Biol 2011; 44:369-76.
-
(2011)
Am J Respir Cell Mol Biol
, vol.44
, pp. 369-376
-
-
Hoegl, S.1
Bachmann, M.2
Scheiermann, P.3
-
19
-
-
45549092326
-
Interleukin 22 receptor 1 expression in pancreas islets
-
Shioya M, Andoh A, Kakinoki S etal. Interleukin 22 receptor 1 expression in pancreas islets. Pancreas 2008; 36:197-9.
-
(2008)
Pancreas
, vol.36
, pp. 197-199
-
-
Shioya, M.1
Andoh, A.2
Kakinoki, S.3
-
20
-
-
0035701768
-
Acinar cells of the pancreas are a target of interleukin-22
-
Aggarwal S, Xie MH, Maruoka M etal. Acinar cells of the pancreas are a target of interleukin-22. J Interferon Cytokine Res 2001; 21:1047-53.
-
(2001)
J Interferon Cytokine Res
, vol.21
, pp. 1047-1053
-
-
Aggarwal, S.1
Xie, M.H.2
Maruoka, M.3
-
21
-
-
0034651583
-
Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9
-
Dumoutier L, Louahed J, Renauld JC. Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9. J Immunol 2000; 164:1814-19.
-
(2000)
J Immunol
, vol.164
, pp. 1814-1819
-
-
Dumoutier, L.1
Louahed, J.2
Renauld, J.C.3
-
22
-
-
0034730141
-
Human interleukin-10 T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor
-
Dumoutier L, Van Roost E, Colau D, Renauld JC. Human interleukin-10 T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor. Proc Natl Acad Sci USA 2000; 97:10144-9.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10144-10149
-
-
Dumoutier, L.1
Van Roost, E.2
Colau, D.3
Renauld, J.C.4
-
23
-
-
0036731485
-
STATs: transcriptional control and biological impact
-
Levy DE, Darnell JE. STATs: transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002; 3:651-62.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 651-662
-
-
Levy, D.E.1
Darnell, J.E.2
-
24
-
-
33947574564
-
Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution
-
Aggarwall BB, Sethi G, Ahn KS etal. Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution. Ann NY Acad Sci 2006; 1091:151-69.
-
(2006)
Ann NY Acad Sci
, vol.1091
, pp. 151-169
-
-
Aggarwall, B.B.1
Sethi, G.2
Ahn, K.S.3
-
25
-
-
11144357779
-
Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells
-
Wang T, Niu G, Kortylewski M etal. Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. Nat Med 2004; 10:48-54.
-
(2004)
Nat Med
, vol.10
, pp. 48-54
-
-
Wang, T.1
Niu, G.2
Kortylewski, M.3
-
26
-
-
33845865825
-
Crosstalk between cancer and immune cells: role of STAT-3 in the tumour microenvironment
-
Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT-3 in the tumour microenvironment. Nat Rev Immunol 2007; 7:41-51.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 41-51
-
-
Yu, H.1
Kortylewski, M.2
Pardoll, D.3
-
27
-
-
11244255857
-
Implication of STAT3 signaling in human colonic cancer cells during intestinal trefoil factor 3 (TFF3)-and vascular endothelial growth factor-mediated cellular invasion and tumor growth
-
Rivat C, Rodrigues S, Bruyneel E etal. Implication of STAT3 signaling in human colonic cancer cells during intestinal trefoil factor 3 (TFF3)-and vascular endothelial growth factor-mediated cellular invasion and tumor growth. Cancer Res 2005; 65:195-202.
-
(2005)
Cancer Res
, vol.65
, pp. 195-202
-
-
Rivat, C.1
Rodrigues, S.2
Bruyneel, E.3
-
28
-
-
69149098253
-
Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?
-
Aggarwal BB, Kunnumakkara AB, Harikumar KB etal. Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship? Ann NY Acad Sci 2009; 1171:59-76.
-
(2009)
Ann NY Acad Sci
, vol.1171
, pp. 59-76
-
-
Aggarwal, B.B.1
Kunnumakkara, A.B.2
Harikumar, K.B.3
-
29
-
-
0035017383
-
Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3-activation, interleukin-2 receptor expression and growth of leukemia Sezary cells
-
Eriksen KW, Kaltoft K, Mikkelsen G etal. Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3-activation, interleukin-2 receptor expression and growth of leukemia Sezary cells. Leukemia 2001; 15:787-93.
-
(2001)
Leukemia
, vol.15
, pp. 787-793
-
-
Eriksen, K.W.1
Kaltoft, K.2
Mikkelsen, G.3
-
31
-
-
33646146734
-
Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-β1 production
-
Ogata H, Chinen T, Yoshida T etal. Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-β1 production. Oncogene 2006; 25:2520-30.
-
(2006)
Oncogene
, vol.25
, pp. 2520-2530
-
-
Ogata, H.1
Chinen, T.2
Yoshida, T.3
-
32
-
-
33645849231
-
Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-beta 1
-
Kinjyo I, Inoue H, Hamano S etal. Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-beta 1. J Exp Med 2006; 203:1021-31.
-
(2006)
J Exp Med
, vol.203
, pp. 1021-1031
-
-
Kinjyo, I.1
Inoue, H.2
Hamano, S.3
-
33
-
-
79251578072
-
Interleukin 22 signaling promotes cell growth in mantle cell lymphoma
-
Gelebart P, Zak Z, Dien-Bard J etal. Interleukin 22 signaling promotes cell growth in mantle cell lymphoma. Transl Oncol 2011; 4:9-19.
-
(2011)
Transl Oncol
, vol.4
, pp. 9-19
-
-
Gelebart, P.1
Zak, Z.2
Dien-Bard, J.3
-
34
-
-
49449100887
-
Aberrant expression of IL-22 receptor 1 and autocrine IL-22 stimulation contribute to tumorigenicity in ALK+ anaplastic large cell lymphoma
-
Bard JD, Gelebart P, Anand M etal. Aberrant expression of IL-22 receptor 1 and autocrine IL-22 stimulation contribute to tumorigenicity in ALK+ anaplastic large cell lymphoma. Leukemia 2008; 22:1595-603.
-
(2008)
Leukemia
, vol.22
, pp. 1595-1603
-
-
Bard, J.D.1
Gelebart, P.2
Anand, M.3
-
35
-
-
58149183235
-
Antiapoptotic activity of autocrine interleukin-22 and therapeutic effects of interleukin-22-small interfering RNA on human lung cancer xenografts
-
Zhang W, Chen Y, Wei H etal. Antiapoptotic activity of autocrine interleukin-22 and therapeutic effects of interleukin-22-small interfering RNA on human lung cancer xenografts. Clin Cancer Res 2008; 14:6432-9.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6432-6439
-
-
Zhang, W.1
Chen, Y.2
Wei, H.3
-
36
-
-
77955862810
-
Elevated IL-17 produced by TH17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma
-
Prabhala RH, Pelluru D, Fulciniti M etal. Elevated IL-17 produced by TH17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma. Blood 2010; 115:5385-92.
-
(2010)
Blood
, vol.115
, pp. 5385-5392
-
-
Prabhala, R.H.1
Pelluru, D.2
Fulciniti, M.3
-
37
-
-
85047695527
-
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
-
Niu G, Wright KL, Huang M etal. Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene 2002; 21:2000-8.
-
(2002)
Oncogene
, vol.21
, pp. 2000-2008
-
-
Niu, G.1
Wright, K.L.2
Huang, M.3
-
38
-
-
80052023399
-
Interleukin-22 promotes human hepatocellular carcinoma by activation of STAT3
-
Jiang R, Tan Z, Deng L etal. Interleukin-22 promotes human hepatocellular carcinoma by activation of STAT3. Hepatology 2011; 54:900-9.
-
(2011)
Hepatology
, vol.54
, pp. 900-909
-
-
Jiang, R.1
Tan, Z.2
Deng, L.3
-
39
-
-
0033557968
-
Tumor-induced interleukin-10 inhibits type 1 immune responses directed at a tumor antigen as well as non-tumor antigen present at the tumor site
-
Halak BK, Maguire HC Jr, Lattime EC. Tumor-induced interleukin-10 inhibits type 1 immune responses directed at a tumor antigen as well as non-tumor antigen present at the tumor site. Cancer Res 1999; 59:911-17.
-
(1999)
Cancer Res
, vol.59
, pp. 911-917
-
-
Halak, B.K.1
Maguire Jr., H.C.2
Lattime, E.C.3
-
41
-
-
79960849046
-
A possible mechanism of impaired NK cytotoxicity in cancer patients: down-regulation of DAP10 by TGF-beta1
-
Lee JC, Lee KM, Ahn YO etal. A possible mechanism of impaired NK cytotoxicity in cancer patients: down-regulation of DAP10 by TGF-beta1. Tumori 2011; 97:350-7.
-
(2011)
Tumori
, vol.97
, pp. 350-357
-
-
Lee, J.C.1
Lee, K.M.2
Ahn, Y.O.3
|