Blockade of fatty acid synthase triggers significant apoptosis in mantle cell lymphoma

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Gelebart, Pascal ^a   Zak, Zoulika ^a   Anand, Mona ^a   Belch, Andrew ^a   Lai, Raymond ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CYCLIN D1; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE INHIBITOR; TETRAHYDROLIPSTATIN; ANTINEOPLASTIC AGENT; CASPASE; CYCLIN D; LACTONE; PROTEINASE; USP2 PROTEIN, HUMAN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; LYMPHOMA CELL; MANTLE CELL LYMPHOMA; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; CELL SURVIVAL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENE SILENCING; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PATHOLOGY; PROMOTER REGION; RNA INTERFERENCE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BETA CATENIN; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; CYCLIN D; ENDOPEPTIDASES; FATTY ACID SYNTHETASE COMPLEX; GENE KNOCKDOWN TECHNIQUES; HUMANS; LACTONES; LYMPHOMA, MANTLE-CELL; PROMOTER REGIONS, GENETIC; RNA INTERFERENCE; TRANSCRIPTION, GENETIC;

EID: 84859226970     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033738     Document Type: Article

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