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Volumn 7, Issue 4, 2012, Pages 578-586

Synthesis and Evaluation of 1-Amino-6-halo-β-carbolines as Antimalarial and Antiprion Agents

(7) Thompson, Mark J a Louth, Jennifer C a Little, Susan M b Jackson, Matthew P a Boursereau, Yohan a Chen, Beining a Coldham, Iain a

a UNIVERSITY OF SHEFFIELD (United Kingdom)

b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE (United Kingdom)

Author keywords

Drug discovery; Heterocycles; Malaria; Medicinal chemistry; Prion disease

Indexed keywords

1 CHLORO 6 FLUORO BETA CARBOLINE; 1,6 DICHLORO BETA CARBOLINE; 6 CHLORO 2,3,4,9 TETRAHYDRO 1H PYRIDO (3,4 BETA) INDOL 1 ONE; 6 CHLORO 2,9 DIHYDRO 1H PYRIDO (3,4 BETA) INDOL 1 ONE; 6 FLUORO 2,3,4,9 TETRAHYDRO 1H PYRIDO (3,4 BETA) INDOL 1 ONE; 6 FLUORO 2,9 DIHYDRO 1H PYRIDO (3,4 BETA) INDOL 1 ONE; 6 HALO BETA CARBOLINE DERRIVATIVE; ANTIINFECTIVE AGENT; ANTIMALARIAL AGENT; CHLOROQUINE; MANZAMINE A; PHENYL 2 (5 CHLORO 1H INDOL 3 YL) ETHYLCARBAMATE; PHENYL 2 (5 FLUORO 1H INDOL 3 YL) ETHYLCARBAMATE; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; PLASMODIUM FALCIPARUM; PRION; PRION DISEASE; PRIORITY JOURNAL;

ANTIMALARIALS; CARBAZOLES; CARBOLINES; CELL LINE; CHLOROQUINE; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE, MICROBIAL; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PLASMODIUM FALCIPARUM; PRIONS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84859194746 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201200002 Document Type: Article

Times cited : (33)

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