Isoniazid resistance without a loss of fitness in Mycobacterium tuberculosis

Nature Communications

Volumn 3, Issue , 2012, Pages

  Lee, Jong Hee ^a   Ammerman, Nicole C ^a   Nolan, Scott ^a   Geiman, Deborah E ^a   Lun, Shichun ^a   Guo, Haidan ^a   Bishai, William R ^a,b,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b AFRICA HEALTH RESEARCH INSTITUTE   (South Africa)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; ISONIAZID; SIGMA FACTOR; SIGMA FACTOR SIGI; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; KATG PROTEIN, MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSTATIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CONTROLLED STUDY; ENZYME SYNTHESIS; EPIDEMIC; FEMALE; FITNESS; GENE OVEREXPRESSION; LUNG TUBERCULOSIS; MOUSE; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; SIGNAL TRANSDUCTION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGY; MACROPHAGE; METABOLISM; MICROBIOLOGY; MULTIDRUG RESISTANT TUBERCULOSIS; PATHOGENICITY; REGULATOR GENE; REGULON; TUBERCULOSIS;

MYCOBACTERIUM TUBERCULOSIS;

ANIMALS; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; CATALASE; DRUG RESISTANCE, MULTIPLE, BACTERIAL; GENES, BACTERIAL; GENES, REGULATOR; ISONIAZID; MACROPHAGES; MICE; MICE, INBRED BALB C; MYCOBACTERIUM TUBERCULOSIS; REGULON; SIGMA FACTOR; TRANSCRIPTION, GENETIC; TUBERCULOSIS; TUBERCULOSIS, MULTIDRUG-RESISTANT;

EID: 84859192077     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms1724     Document Type: Article

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