Sensitivity control through attenuation of signal transfer efficiency by negative regulation of cellular signalling

Nature Communications

Volumn 3, Issue , 2012, Pages

  Toyoshima, Yu ^a   Kakuda, Hiroaki ^a   Fujita, Kazuhiro A ^a,c   Uda, Shinsuke ^a   Kuroda, Shinya ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c Systems Biology Institute   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; PROTEIN KINASE B; EPIDERMAL GROWTH FACTOR RECEPTOR; LAPATINIB; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE INHIBITOR; QUINAZOLINE DERIVATIVE;

ARTICLE; BIOCHEMISTRY; CELL LINE; CHEMICAL REACTION; ENZYME REGULATION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; CELL STRAIN 3T3; DRUG ANTAGONISM; HELA CELL; METABOLISM; MOUSE; RAT; TUMOR CELL LINE;

3T3 CELLS; ANIMALS; CELL LINE; CELL LINE, TUMOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HELA CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE; MODELS, BIOLOGICAL; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; QUINAZOLINES; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 84859167118     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms1745     Document Type: Article

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