Improved CEDIA® benzodiazepine assay eliminates sertraline crossreactivity

Journal of Analytical Toxicology

Volumn 21, Issue 1, 1997, Pages 32-35

  Fitzgerald, Robert L ^a   Herold, David A ^b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; BENZODIAZEPINE; SERTRALINE; 1 NAPHTHYLAMINE; BENZODIAZEPINE DERIVATIVE; DRUG DERIVATIVE;

ARTICLE; CLONE; CROSS REACTION; DRUG DETERMINATION; ELECTRON CAPTURE DETECTION; GAS CHROMATOGRAPHY; IMMUNOASSAY; MASS SPECTROMETRY; CHEMISTRY; COMPARATIVE STUDY; ENZYME MULTIPLIED IMMUNOASSAY TECHNIQUE; HUMAN; IMMUNOLOGY; MASS FRAGMENTOGRAPHY; METHODOLOGY; PREDICTION AND FORECASTING; SENSITIVITY AND SPECIFICITY; SUBSTANCE ABUSE; URINE;

1-NAPHTHYLAMINE; ANTIDEPRESSIVE AGENTS; BENZODIAZEPINES; CROSS REACTIONS; ENZYME MULTIPLIED IMMUNOASSAY TECHNIQUE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; PREDICTIVE VALUE OF TESTS; SENSITIVITY AND SPECIFICITY; SERTRALINE; SUBSTANCE ABUSE DETECTION; URINE;

EID: 0030614394     PISSN: 01464760     EISSN: None     Source Type: Journal    
DOI: 10.1093/jat/21.1.32     Document Type: Article

References (8)

1. R.L. Fitzgerald, S. Priem, T. Leech, K. Schlussel, and D.A. Herold. Comparison of CEDIA and ONLINE drugs of abuse assays. Clin. Chem. 41(S6): S125 (1995).
2. R.L. Fitzgerald, D.A. Rexin, and D.A. Herold. Benzodiazepine analysis by negative chemical ionization gas chromatography/mass spectrometry. J. Anal. Toxicol. 17: 342-47 (1993).
3. N.F. Bellet, H.A. Scholtz, M.L. Opel, E. Padilla, F.R. Galloway, and P. Khanna. Improved CEDIA® DAU benzodiazepine assay for urine drug testing. J. Anal. Toxicol. 20: 76 (1996).
4. S.J. Warrington. Clinical implications of the pharmacology of sertraline. Int. Clin. Psychopharmacol. 2: 11-21 (1991).
5. B. Levine, A.J. Jenkins, and J.E. Smialek. Distribution of sertraline in postmortem cases. J. Forensic Sci. 18: 272-74 (1994).
6. L.M. Tremaine, W.M. Welch, and R.A. Ronfeld. Metabolism and disposition of the 5-hydroxytryptamine uptake blocker sertraline in the rat and dog. Drug Metab. Dispos. 17: 542-50 (1989).
7. R.L. Fitzgerald, D. Rexin, and D.A. Herold. Detecting benzodiazepines: Immunoassays compared with negative chemical ionization gas chromatography/mass spectrometry. Clin. Chem. 40: 373-80 (1994).
8. P.D. Camara, L. Audette, K. Velletri, P. Breitenbecher, M. Rosner, and W.C. Griffiths. False positive immunoassay results for urine benzodiazepine in patients receiving oxaprozin (Daypro). Clin. Chem. 41: 115-16 (1995).