Identification of talinolol metabolites in urine of man, dog, rat and mouse after oral administration by high-performance liquid chromatography-thermospray tandem mass spectrometry

Journal of Mass Spectrometry

Volumn 31, Issue 12, 1996, Pages 1371-1381

  Schupke, Hubert ^a   Hempel, Roland ^a   Eckardt, Rudolf ^a   Kronbach, Thomas ^a  

^a ASTA MEDICA AG   (Germany)

Author keywords

blocking drugs; Cyclohexyl urea derivatives; HPLC MS MS; Metabolism; Talinolol

Indexed keywords

DRUG METABOLITE; TALINOLOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; MASS SPECTROMETRY; METABOLITE; MOUSE; NONHUMAN; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; URINALYSIS;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; HUMANS; HYDROLYSIS; MASS SPECTROMETRY; MICE; PROPANOLAMINES; RATS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0030461691     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9888(199612)31:12<1371::AID-JMS433>3.0.CO;2-4     Document Type: Article

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