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Volumn 90, Issue 13-14, 2012, Pages 476-483

Improvement of the energy supply and contractile function in normal and ischemic rat hearts by dietary orotic acid

Author keywords

Cardiac metabolism; Fatty acid oxidation; Glycolytic flux; Isolated perfused heart; Lipoprotein lipase; PPAR

Indexed keywords

CARDIOVASCULAR AGENT; CHOLESTEROL; FATTY ACID; GLUCOSE; GLUCOSE TRANSPORTER 4; GLYCOGEN; GLYCOLYTIC ENZYME; LACTIC ACID; LIPOPROTEIN LIPASE; OROTIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTECTIVE AGENT; TRIACYLGLYCEROL;

EID: 84859107103     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.12.012     Document Type: Article
Times cited : (12)

References (39)
  • 2
    • 27144529361 scopus 로고    scopus 로고
    • Free fatty acids repress the GLUT4 gene expression in cardiac muscle via novel response elements
    • DOI 10.1074/jbc.M502740200
    • M. Armoni, C. Harel, F. Bar-Yoseph, S. Milo, and E. Karnieli Free fatty acids repress the GLUT4 gene expression in cardiac muscle via novel response elements J Biol Chem 280 2005 34786 34795 (Pubitemid 41504612)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.41 , pp. 34786-34795
    • Armoni, M.1    Harel, C.2    Bar-Yoseph, F.3    Milo, S.4    Karnieli, E.5
  • 3
    • 0014512187 scopus 로고
    • Simple liquid-liquid partition system for isolation of labeled oleic acid from mixtures with glycerides
    • P. Belfrage, and M. Vaughan Simple liquid-liquid partition system for isolation of labeled oleic acid from mixtures with glycerides J Lipid Res 10 1969 341 344
    • (1969) J Lipid Res , vol.10 , pp. 341-344
    • Belfrage, P.1    Vaughan, M.2
  • 4
    • 0034890019 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-alpha ligands inhibit cardiac lipoprotein lipase activity
    • R. Carroll, and D.L. Severson Peroxisome proliferator-activated receptor-alpha ligands inhibit cardiac lipoprotein lipase activity Am J Physiol Heart Circ Physiol 281 2001 H888 H894
    • (2001) Am J Physiol Heart Circ Physiol , vol.281
    • Carroll, R.1    Severson, D.L.2
  • 6
    • 0031898246 scopus 로고    scopus 로고
    • Metabolic inhibition in the perfused rat heart: Evidence for glycolytic requirement for normal sodium homeostasis
    • J. Dizon, D. Burkhoff, J. Tauskela, J. Whang, P. Cannon, and J. Katz Metabolic inhibition in the perfused rat heart: evidence for glycolytic requirement for normal sodium homeostasis Am J Physiol 274 1998 H1082 H1089
    • (1998) Am J Physiol , vol.274
    • Dizon, J.1    Burkhoff, D.2    Tauskela, J.3    Whang, J.4    Cannon, P.5    Katz, J.6
  • 7
    • 0027479061 scopus 로고
    • The effect of orotic acid treatment on the energy and carbohydrate metabolism of the hypertrophying rat heart
    • DOI 10.1016/0020-711X(93)90004-X
    • J.A. Donohoe, F.L. Rosenfeldt, C.M. Munsch, and J.F. Williams The effect of orotic acid treatment on the energy and carbohydrate metabolism of the hypertrophying rat heart Int J Biochem 25 2 1993 163 182 (Pubitemid 23045828)
    • (1993) International Journal of Biochemistry , vol.25 , Issue.2 , pp. 163-182
    • Donohoe, J.A.1    Rosenfeldt, F.L.2    Munsch, C.M.3    Williams, J.F.4
  • 8
    • 4444226906 scopus 로고    scopus 로고
    • Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation
    • J.R. Dyck, J.F. Cheng, W.C. Stanley, R. Barr, M.P. Chandler, and S. Brown Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation Circ Res 94 2004 e78 e84
    • (2004) Circ Res , vol.94
    • Dyck, J.R.1    Cheng, J.F.2    Stanley, W.C.3    Barr, R.4    Chandler, M.P.5    Brown, S.6
  • 9
    • 84859108183 scopus 로고    scopus 로고
    • Interpretaciones recientes sobre el metabolismo lipídico en la resistencia a la insulina
    • Y.R. Enriquez Interpretaciones recientes sobre el metabolismo lipídico en la resistencia a la insulina Rev Cubana Aliment Nutr 16 2002 54 62
    • (2002) Rev Cubana Aliment Nutr , vol.16 , pp. 54-62
    • Enriquez, Y.R.1
  • 10
    • 3042780233 scopus 로고    scopus 로고
    • Differential regulation of fatty acid trapping in mouse adipose tissue and muscle by ASP
    • M. Faraj, and K. Cianflone Differential regulation of fatty acid trapping in mouse adipose tissue and muscle by ASP Am J Physiol Endocrinol Metab 287 2004 E150 E159
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Faraj, M.1    Cianflone, K.2
  • 11
    • 0032005848 scopus 로고    scopus 로고
    • Effects of orotic acid on ischaemic/reperfused myocardial function and glycogen content in isolated working rat hearts
    • DOI 10.1006/phrs.1997.0274
    • P. Ferdinandy, T. Fazekas, and E. Kadar Effects of orotic acid on ischaemic/reperfused myocardial function and glycogen content in isolated working rat hearts Pharmacol Res 37 1998 111 114 (Pubitemid 28138402)
    • (1998) Pharmacological Research , vol.37 , Issue.2 , pp. 111-114
    • Ferdinandy, P.1    Fazekas, T.2    Kadar, E.3
  • 13
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • J. Folch, M. Lees, and G.H. Sloane Stanley A simple method for the isolation and purification of total lipides from animal tissues J Biol Chem 226 1957 497 509
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 14
    • 23044450269 scopus 로고    scopus 로고
    • Activation of PPARgamma enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats
    • L.S. Golfman, C.R. Wilson, S. Sharma, M. Burgmaier, M.E. Young, and P.H. Guthrie Activation of PPARgamma enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats Am J Physiol Endocrinol Metab 289 2005 E328 E336
    • (2005) Am J Physiol Endocrinol Metab , vol.289
    • Golfman, L.S.1    Wilson, C.R.2    Sharma, S.3    Burgmaier, M.4    Young, M.E.5    Guthrie, P.H.6
  • 15
    • 0036401857 scopus 로고    scopus 로고
    • Fatty acid transport across membranes: Relevance to nutrition and metabolic pathology
    • DOI 10.1146/annurev.nutr.22.020402.130846
    • T. Hajri, and N.A. Abumrad Fatty acid transport across membranes: relevance to nutrition and metabolic pathology Annu Rev Nutr 22 2002 383 415 (Pubitemid 35221466)
    • (2002) Annual Review of Nutrition , vol.22 , pp. 383-415
    • Hajri, T.1    Abumrad, N.A.2
  • 16
    • 0022556166 scopus 로고
    • Preparation, characterization, and measurement of lipoprotein lipase
    • P.H. Iverius, and A.M. Ostlund-Lindqvist Preparation, characterization, and measurement of lipoprotein lipase Methods Enzymol 129 1986 691 704
    • (1986) Methods Enzymol , vol.129 , pp. 691-704
    • Iverius, P.H.1    Ostlund-Lindqvist, A.M.2
  • 17
    • 0021894480 scopus 로고
    • Nucleotide metabolism and cellular damage in myocardial ischemia
    • R.B. Jennings, and C. Steenbergen Jr. Nucleotide metabolism and cellular damage in myocardial ischemia Annu Rev Physiol 47 1985 727 749 (Pubitemid 15142408)
    • (1985) Annual Review of Physiology , vol.47 , pp. 727-749
    • Jennings, R.B.1    Steenbergen Jr., C.2
  • 18
    • 0004212171 scopus 로고    scopus 로고
    • 4th ed. Lippincott Williams & Wilkins Philadelphia
    • A.M. Katz Physiology of the heart 4th ed. 2006 Lippincott Williams & Wilkins Philadelphia
    • (2006) Physiology of the Heart
    • Katz, A.M.1
  • 19
    • 0019082782 scopus 로고
    • Glucose homeostasis in a carnivorous animal (cat) and in rats fed a high-protein diet
    • I.C. Kettelhut, M.C. Foss, and R.H. Migliorini Glucose homeostasis in a carnivorous animal (cat) and in rats fed a high-protein diet Am J Physiol 239 1980 R437 R444
    • (1980) Am J Physiol , vol.239
    • Kettelhut, I.C.1    Foss, M.C.2    Migliorini, R.H.3
  • 20
    • 0032145896 scopus 로고    scopus 로고
    • Glucose delivery is a major determinant of glucose utilisation in the ischemic myocardium with a residual coronary flow
    • DOI 10.1016/S0008-6363(98)00100-X, PII S000863639800100X
    • L.M. King, and L.H. Opie Glucose delivery is a major determinant of glucose utilisation in the ischemic myocardium with a residual coronary flow Cardiovasc Res 39 1998 381 392 (Pubitemid 28346534)
    • (1998) Cardiovascular Research , vol.39 , Issue.2 , pp. 381-392
    • King, L.M.1    Opie, L.H.2
  • 22
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(- Delta Delta C(T)) method Methods 25 2001 402 408 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 23
    • 0018173865 scopus 로고
    • Ventricular arrhythmias associated with coronary artery occlusion and reperfusion in the isolated perfused rat heart: A model for assessment of antifibrillatory action of antiarrhythmic agents
    • W.F. Lubbe, P.S. Daries, and L.H. Opie Ventricular arrhythmias associated with coronary artery occlusion and reperfusion in the isolated perfused rat heart: a model for assessment of antifibrillatory action of antiarrhythmic agents Cardiovasc Res 12 1978 212 220 (Pubitemid 8352598)
    • (1978) Cardiovascular Research , vol.12 , Issue.4 , pp. 212-220
    • Lubbe, W.F.1    Daries, P.S.2    Opie, L.H.3
  • 24
    • 38349019479 scopus 로고    scopus 로고
    • Identification of protein kinase D as a novel contraction-activated kinase linked to GLUT4-mediated glucose uptake, independent of AMPK
    • J.J.F.P. Luiken, D. Vertommen, S.L.M. Coort, D.D.J. Habets, M. Hasnaoui, and M.M.L. Pelsers Identification of protein kinase D as a novel contraction-activated kinase linked to GLUT4-mediated glucose uptake, independent of AMPK Cell Signal 20 2008 543 556
    • (2008) Cell Signal , vol.20 , pp. 543-556
    • Luiken, J.J.F.P.1    Vertommen, D.2    Coort, S.L.M.3    Habets, D.D.J.4    Hasnaoui, M.5    Pelsers, M.M.L.6
  • 25
    • 0036303805 scopus 로고    scopus 로고
    • Dietary orotic acid affects antioxidant enzyme mRNA levels and oxidative damage to lipids and proteins in rat liver
    • DOI 10.1016/S0955-2863(02)00182-1, PII S0955286302001821
    • M. Morifuji, and Y. Aoyama Dietary orotic acid affects antioxidant enzyme mRNA levels and oxidative damage to lipids and proteins in rat liver J Nutr Biochem 13 2002 403 410 (Pubitemid 34733009)
    • (2002) Journal of Nutritional Biochemistry , vol.13 , Issue.7 , pp. 403-410
    • Morifuji, M.1    Aoyama, Y.2
  • 26
    • 0024357797 scopus 로고
    • The impaired tolerance of the recently infarcted rat heart to cardioplegic arrest: The protective effect of orotic acid
    • DOI 10.1016/0022-2828(89)90713-X
    • C. Munsch, J.F. Williams, and F.L. Rosenfeldt The impaired tolerance of the recently infarcted rat heart to cardioplegic arrest: the protective effect of orotic acid J Mol Cell Cardiol 21 8 1989 751 754 (Pubitemid 19225942)
    • (1989) Journal of Molecular and Cellular Cardiology , vol.21 , Issue.8 , pp. 751-754
    • Munsch, C.1    Williams, J.F.2    Rosenfeldt, F.L.3
  • 27
    • 0017202148 scopus 로고
    • A stable, radioactive substrate emulsion for assay of lipoprotein lipase
    • P. Nilsson-Ehle, and M.C. Schotz A stable, radioactive substrate emulsion for assay of lipoprotein lipase J Lipid Res 17 1976 536 541
    • (1976) J Lipid Res , vol.17 , pp. 536-541
    • Nilsson-Ehle, P.1    Schotz, M.C.2
  • 28
    • 4043063526 scopus 로고    scopus 로고
    • Utilization of triacylglycerol-rich lipoproteins by the working rat heart: Routes of uptake and metabolic fates
    • DOI 10.1113/jphysiol.2004.061473
    • Y.G. Niu, D. Hauton, and R.D. Evans Utilization of triacylglycerol-rich lipoproteins by the working rat heart: routes of uptake and metabolic fates J Physiol 558 2004 225 237 (Pubitemid 39077403)
    • (2004) Journal of Physiology , vol.558 , Issue.1 , pp. 225-237
    • Niu, Y.-G.1    Hauton, D.2    Evans, R.D.3
  • 32
    • 0031661865 scopus 로고    scopus 로고
    • Metabolic supplementation with orotic acid and magnesium orotate
    • F.L. Rosenfeldt Metabolic supplementation with orotic acid and magnesium orotate Cardiovasc Drugs Ther 12 Suppl. 2 1998 147 152
    • (1998) Cardiovasc Drugs Ther , vol.12 , Issue.SUPPL. 2 , pp. 147-152
    • Rosenfeldt, F.L.1
  • 34
    • 0037402313 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) control of fatty acid and glucose metabolism in the ischemic heart
    • DOI 10.1016/S0163-7827(02)00065-6
    • N. Sambandam, and G.D. Lopaschuk AMP-activated protein kinase (AMPK) control of fatty acid and glucose metabolism in the ischemic heart Prog Lipid Res 42 2003 238 256 (Pubitemid 36411693)
    • (2003) Progress in Lipid Research , vol.42 , Issue.3 , pp. 238-256
    • Sambandam, N.1    Lopaschuk, G.D.2
  • 36
    • 6044220129 scopus 로고    scopus 로고
    • Evidence for mitochondrial thioesterase 1 as a peroxisome proliferator-activated receptor-alpha-regulated gene in cardiac and skeletal muscle
    • M.A. Stavinoha, J.W. RaySpellicy, M.F. Essop, C. Graveleau, E.D. Abel, and M.L. Hart-Sailors Evidence for mitochondrial thioesterase 1 as a peroxisome proliferator-activated receptor-alpha-regulated gene in cardiac and skeletal muscle Am J Physiol Endocrinol Metab 287 2004 E888 E895
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Stavinoha, M.A.1    Rayspellicy, J.W.2    Essop, M.F.3    Graveleau, C.4    Abel, E.D.5    Hart-Sailors, M.L.6
  • 37
    • 0037343188 scopus 로고    scopus 로고
    • Contribution of fatty acids released from lipolysis of plasma triglycerides to total plasma fatty acid flux and tissue-specific fatty acid uptake
    • DOI 10.2337/diabetes.52.3.614
    • B. Teusink, P.J. Voshol, V.E. Dahlmans, P.C. Rensen, H. Pijl, and J.A. Romijn Contribution of fatty acids released from lipolysis of plasma triglycerides to total plasma fatty acid flux and tissue-specific fatty acid uptake Diabetes 52 2003 614 620 (Pubitemid 36323566)
    • (2003) Diabetes , vol.52 , Issue.3 , pp. 614-620
    • Teusink, B.1    Voshol, P.J.2    Dahlmans, V.E.H.3    Rensen, P.C.N.4    Pijl, H.5    Romijn, J.A.6    Havekes, L.M.7
  • 38
    • 0033772261 scopus 로고    scopus 로고
    • Proliferation of mitochondria and gene expression of carnitine palmitoyltransferase and fatty acyl-CoA oxidase in rat skeletal muscle, heart and liver by hypolipidemic fatty acids
    • G.K. Totland, L. Madsen, B. Klementsen, H. Vaagenes, H. Kryvi, and L. Froyland Proliferation of mitochondria and gene expression of carnitine palmitoyltransferase and fatty acyl-CoA oxidase in rat skeletal muscle, heart and liver by hypolipidemic fatty acids Biol Cell 92 2000 317 329
    • (2000) Biol Cell , vol.92 , pp. 317-329
    • Totland, G.K.1    Madsen, L.2    Klementsen, B.3    Vaagenes, H.4    Kryvi, H.5    Froyland, L.6
  • 39
    • 33845585832 scopus 로고    scopus 로고
    • Thematic review series: Systems biology approaches to metabolic and cardiovascular disorders: Network perspectives of cardiovascular metabolism
    • DOI 10.1194/jlr.R600023-JLR200
    • J.N. Weiss, L. Yang, and Z. Qu Systems biology approaches to metabolic and cardiovascular disorders: network perspectives of cardiovascular metabolism J Lipid Res 47 2006 2355 2366 (Pubitemid 44936097)
    • (2006) Journal of Lipid Research , vol.47 , Issue.11 , pp. 2355-2366
    • Weiss, J.N.1    Yang, L.2    Qu, Z.3


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