Glucose-Insulin Infusion Improves Cardiac Function during Fetal Tachycardia

Journal of the American College of Cardiology

Volumn 43, Issue 3, 2004, Pages 445-452

  Schmidt, Michael Rahbek ^a   Kristiansen, Steen Buus ^a   White, Paul ^b   Smerup, Morten ^a   Bøtker, Hans Erik ^a   Vogel, Michael ^c   Hjortdal, Vibeke ^a   Sørensen, Keld ^a   Redington, Andrew ^d  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b PAPWORTH HOSPITAL   (United Kingdom)

^c GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; ENERGY YIELD; FETUS; FETUS DEATH; FETUS DISEASE; HEART FAILURE; HEART FUNCTION; HEART MUSCLE METABOLISM; HEART PACING; ISOLATED HEART; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SWINE; TACHYCARDIA;

EID: 0842309110     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2003.08.041     Document Type: Article

References (23)

1. Simpson J.M., Sharland G.K. Fetal tachycardias management and outcome of 127 consecutive cases . Heart. 79:1998;576-581.
2. Lingman G., Lundstrom N.R., Marsal K., Ohrlander S. Fetal cardiac arrhythmia clinical outcome in 113 cases . Acta Obstet Gynecol Scand. 65:1986;263-267.
3. Hoerter J.A., Opie L.H. Perinatal changes in glycolytic function in response to hypoxia in the incubated or perfused rat heart. Biol Neonate. 33:1978;144-161.
4. Fisher D.J. Oxygenation and metabolism in the developing heart. Semin Perinatol. 8:1984;217-225.
5. Ascuitto R.J., Ross-Ascuitto N.T. Substrate metabolism in the developing heart. Semin Perinatol. 20:1996;542-563.
6. Werner J.C., Whitman V., Vary T.C., Fripp R.R., Musselman J., Schuler H.G. Fatty acid and glucose utilization in isolated, working newborn pig hearts. Am J Physiol. 244:1983;E19-E23.
7. Fisher D.J., Heymann M.A., Rudolph A.M. Myocardial consumption of oxygen and carbohydrates in newborn sheep. Pediatr Res. 15:1981;843-846.
8. Visscher MB, Müller EA. Influence of insulin upon mammalian heart. J Physiol 1926;62:341-8.
9. Doenst T., Richwine R.T., Bray M.S., Goodwin G.W., Frazier O.H., Taegtmeyer H. Insulin improves functional and metabolic recovery of reperfused working rat heart. Ann Thorac Surg. 67:1999;1682-1688.
10. Majid P.A., Sharma B., Meeran M.K., Taylor S.H. Insulin and glucose in the treatment of heart-failure. Lancet. 2:1972;937-941.
11. Rieker R.P., Lee J.C., Downing S.E. Positive inotropic action of insulin on piglet heart. Yale J Biol Med. 48:1975;353-359.
12. Davis K.L., Mehlhorn U., Schertel E.R., et al. Variation in tau, the time constant for isovolumic relaxation, along the left ventricular base-to-apex axis. Basic Res Cardiol. 94:1999;41-48.
13. Botker H.E., Helligso P., Kimose H.H., Thomassen A.R., Nielsen T.T. Determination of high energy phosphates and glycogen in cardiac and skeletal muscle biopsies, with special reference to influence of biopsy technique and delayed freezing. Cardiovasc Res. 28:1994;524-527.
14. Matthews J.N., Altman D.G., Campbell M.J., Royston P. Analysis of serial measurements in medical research. BMJ. 300:1990;230-235.
15. Weil S.R., Russo P.A., Heckman J.L., Balsara R.K., Pasiecki V., Dunn J.M. Pressure-volume relationship of the fetal lamb heart. Ann Thorac Surg. 55:1993;470-475.
16. Fisher D.J., Gross D.M. The effect of atrial pacing-induced tachycardia on left ventricular contractile function in conscious newborn and adult sheep. Pediatr Res. 17:1983;651-656.
17. Kass D.A., Maughan W.L., Guo Z.M., Kono A., Sunagawa K., Sagawa K. Comparative influence of load versus inotropic states on indexes of ventricular contractility experimental and theoretical analysis based on pressure-volume relationships . Circulation. 76:1987;1422-1436.
18. Ascuitto R.J., Joyce J.J., Ross-Ascuitto N.T. Mechanical function and substrate oxidation in the neonatal pig heart subjected to pacing-induced tachycardia. Mol Genet Metab. 66:1999;212-223.
19. Rolph T.P., Jones C.T. Regulation of glycolytic flux in the heart of the fetal guinea pig. J Dev Physiol. 5:1983;31-49.
20. Dawes G.S. Foetal and Neonatal Physiology. 1968;Chicago Medical Publishers, Chicago, IL. 94.
21. Jones C.T., Rolph T.P. Metabolism during fetal life a functional assessment of metabolic development . Physiol Rev. 65:1985;357-430.
22. Postic C., Leturque A., Printz R.L., et al. Development and regulation of glucose transporter and hexokinase expression in rat. Am J Physiol. 266:1994;E548-559.
23. Ito S., Magee L., Smallhorn J. Drug therapy for fetal arrhythmias. Clin Perinatol. 21:1994;543-572.