Glucose delivery is a major determinant of glucose utilisation in the ischemic myocardium with a residual coronary flow

Cardiovascular Research

Volumn 39, Issue 2, 1998, Pages 381-392

  King, Linda M ^a   Opie, Lionel H ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Glycolysis; Ischemia; Metabolic regulation; Preconditioning; Rat

Indexed keywords

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CELL LEVEL; CONCENTRATION (PARAMETERS); CORONARY ARTERY BLOOD FLOW; FLOW RATE; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; HEART MUSCLE ISCHEMIA; ISOLATED HEART; MALE; METABOLITE; NONHUMAN; PRIORITY JOURNAL; RAT; STEADY STATE;

EID: 0032145896     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(98)00100-X     Document Type: Article

References (41)

1. [1] Rovetto MJ, Lamberton WF, Neely JR. Mechanisms of glycolytic inhibition in ischemic rat hearts. Circ Res 1975;37:742-751.
2. [2] Mochizuki S, Neely JR. Control of glyceraldehyde-3-phosphate dehydrogenase in cardiac muscle. J Mol Cell Cardiol 1979;11:221-236.
3. [3] Neely JR, Rovetto MJ, Whitmer JT, et al. Effects of ischemia on the function and metabolism of the isolated working rat heart. Am J Physiol 1973;225:651-658.
4. [4] Neely JR, Whitmer JT, Rovetto MJ. Effect of coronary blood flow on glycolytic flux and intracellular pH in isolated rat hearts. Circ Res 1975;37:733-741.
5. [5] Rovetto MJ, Whitmer JT, Neely JR. Comparison of the effects of anoxia and whole heart ischemia on carbohydrate utilisation in isolated working rat hearts. Circ Res 1973;32:699-711.
6. 18F-labelled fluorodeoxyglucose and N-13 ammonia. Circulation 1983;67:766-778.
7. [7] Di Carli M, Asgarzadie F, Schelbert HR, et al. Quantitative relation between myocardial viability and improvement in heart failure symptoms after revascularization in patients with ischemic cardiomyopathy. Circulation 1995;92:3436-3444.
8. [8] Stanley WC, Hall JL, Stone CK, et al. Acute myocardial ischemia causes a transmural gradient in glucose extraction but not glucose uptake. Am J Physiol 1992;262:H91-H96.
9. [9] Sun DQ, Nguyen N, DeGrado TR, et al. Ischemia induces translocation of the insulin-responsive glucose transporter GLUT4 to the plasma membrane of cardiac myocytes. Circulation 1994;89:793-798.
10. [10] Young LH, Renfu Y, Russell R, et al. Low-flow ischemia leads to translocation of canine heart GLUT-4 and GLUT-1 glucose transporters to the sarcolemma in vivo. Circulation 1997;95:415-422.
11. [11] Owen P, Dennis S, Opie LH. Glucose flux rate regulates onset of ischemic contracture in globally underperfused rat hearts. Circ Res 1990;66:344-354.
12. [12] King LM, Boucher F, Opie LH. Coronary flow and glucose delivery as determinants of contracture in the ischemic myocardium. J Mol Cell Cardiol 1995;27:701-720.
13. [13] Bergmeyer HU, editor. Methods of enzymatic analysis. New York: Academic Press, 1974.
14. [14] Good CA, Kramer H, Somogyi M. The determination of glycogen. J Biol Chem 1933;100:485-496.
15. [15] King LM, Opie LH. Does preconditioning act by glycogen depletion in the isolated rat heart? J Mol Cell Cardiol 1996;28:2305-2321.
16. [16] De Jong JW, Cargnoni A, Bradamente S, et al. Intermittent vs continuous ischemia decelerates adenylate breakdown and prevents norepinephrine release in reperfused rabbit heart. J Mol Cell Cardiol 1995;27:659-671.
17. [17] Jennings RB, Reimer KA. The cell biology of acute myocardial ischaemia. Annu Rev Med 1991;42:225-246.
18. [18] Chance B, Holmes W, Higgins J, et al. Localization of interaction sites in multicomponent transfer systems: theorems derived from analogues. Nature 1958;182:1190-1193.
19. [19] Kalff V, Schwaiger M, Nguyen N, et al. The relationship between myocardial blood flow and glucose uptake in ischemic canine myocardium determined with fluorine-18-deoxyglucose. J Nucl Med 1992;33:1346-1353.
20. 3 (Abstract). Circulation 1983;68(Suppl III):III-387.
21. [21] Kohn MC, Garfinkel D. Computer simulation of entry into glycolysis and lactate output in the ischaemic rat heart. J Mol Cell Cardiol 1978;10:779-796.
22. [22] Newsholme EA, Crabhee B. Theoretical principles in the approaches to control of metabolic pathways and their application to glycolysis in muscle. J Mol Cell Cardiol 1979;11:839-856.
23. [23] Kashiwaya Y, Sato K, Tsuchiya N, et al. Control of glucose utilization in working perfused rat heart. J Biol Chem 1994;269:25502-25514.
24. [24] Manchester J, Kong X, Nerbonne J, et al. Glucose transport and phosphorylation in single cardiac myocytes: rate-limiting steps in glucose metabolism. Am J Physiol 1994;266:E326-E333.
25. [25] Srere P. Complexities of metabolic regulation. Trends Biochem Sci 1994;19:519-520.
26. [26] Welch GR, Easterby JS. Metabolic channelling versus free diffusion: transition-time analysis. Trend Biochem Sci 1994;19:193-197.
27. [27] Taegtmeyer H. Energy metabolism of the heart: from basic concepts to clinical applications. Curr Prob Cardiol 1994;19:59-113.
28. [28] Opie LH, Mansford KRL, Owen P. Effects of increased work on glycolysis and adenine nucleotides in the perfused heart of normal and diabetic rats. Biochem J 1971;124:475-490.
29. [29] Depré C, Vanoverschelde J-L, Goudemant J-F, et al. Protection against ischemic injury by nonvasoactive concentrations of nitric oxide synthase inhibitors in the perfused rabbit heart. Circulation 1995;92:1911-1918.
30. [30] Bolukoglu H, Goodwin GW, Guthrie PH, et al. Metabolic fate of glucose in reversible low-flow ischemia of the isolated working rat heart. Am J Physiol 1996;270:H817-H826.
31. [31] Kübier W, Spieckermann PG. Regulation of glycolysis in the ischemic and the anoxic myocardium. J Mol Cell Cardiol 1970;1:351-377.
32. [32] Ui M. A role of phosphofructokinase in pH-dependent regulation of glycolysis. Biochim Biophys Acta 1966;124:310-322.
33. [33] Kuschinsky W, Bunger R, Schrock H, et al. Local glucose utilisation and local blood flow in hearts of awake rats. Basic Res Cardiol 1993;88:233-249.
34. [34] Ren-fu X, Hu X, Russell R, et al. Translocation of glucose transporter isoforms in vivo: effects of hyperinsulinaemia and low-flow ischemia in the canine heart. Circulation 1995;92(Suppl I):I-769.
35. [35] James DE. The mammalian facilitative glucose transporter family. News Physiol Sci 1995;10:67-71.
36. [36] King LM, Opie LH. Low-flow ischaemia abolishes the protective effect of preconditioning on stunning (abstract). J Mol Cell Cardiol 1995;27:A264.
37. [37] Angello DA, Berne RM, Coddington NM. Adenosine and insulin mediate glucose uptake in normoxic rat hearts by different mechanisms. Am J Physiol 1993;265:H880-H885.
38. [38] Rattigan S, Appleby GJ, Clark MG. Insulin-like action of catecholamines and Ca to stimulate glucose transport and GLUT4 translocation in perfused rat heart. Biochem Biophys Acta 1991;1094:217-223.
39. [39] Goodwin GW, Arteaga JR, Taegtmeyer H. Glycogen turnover in the isolated working rat heart. J Biol Chem 1995;270:9234-9240.
40. [40] Cross HR, Clarke K, Opie LH, et al. Is lactate-induced myocardial ischaemic injury mediated by decreased pH or increased intracellular lactate?. J Mol Cell Cardiol 1995;27:1369-1381.
41. [41] Depré C, Veitch K, Hue L. Role of fructose 2,6-bisphosphate in the control of glycolysis. Stimulation of glycogen synthesis by lactate in the isolated working rat heart. Acta Cardiol 1993;48:147-164.