cDNA cloning and analysis of tissue-specific expression of mouse peroxisomal straight-chain acyl-CoA oxidase

European Journal of Biochemistry

Volumn 267, Issue 4, 2000, Pages 1254-1260

  Nöhammer, Christa ^a   El Shabrawi, Yosuf ^a   Schauer, Silvia ^a   Hiden, Michaela ^b   Berger, Johannes ^c   Forss Petter, Sonja ^c   Winter, Elke ^a   Eferl, Robert ^a   Zechner, Rudolf ^b   Hoefler, Gerald ^a  

^a Departments of Pathology   (Austria)

^b UNIVERSITY OF GRAZ   (Austria)

^c UNIVERSITY OF VIENNA   (Austria)

Author keywords

Acyl CoA oxidase; Fatty acids; Peroxisomes; PPAR ; oxidation

Indexed keywords

ACYL COENZYME A; COMPLEMENTARY DNA; HYDROGEN PEROXIDE; MESSENGER RNA; OXIDOREDUCTASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; ENZYME ACTIVITY; FATTY ACID OXIDATION; MOLECULAR CLONING; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION; TISSUE SPECIFICITY;

ACYL-COA OXIDASE; AMINO ACID MOTIFS; ANIMALS; BLOTTING, WESTERN; BRAIN; CLONING, MOLECULAR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; ISOENZYMES; LIVER; MICE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; ORGAN SPECIFICITY; OXIDOREDUCTASES; PEROXISOMES; PROTEIN SORTING SIGNALS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 2142647935     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01128.x     Document Type: Article

References (42)

1. 1. Mannaerts, G.P. & Van-Veldhoven, P.P. (1996) Functions and organization of peroxisomal beta-oxidation. Ann. NY Acad. Sci. 804, 99-115.
2. 2. Van-den-Bosch, H., Schutgens, R.B., Wanders, R.J. & Tager, J.M. (1992) Biochemistry of peroxisomes. Annu. Rev. Biochem. 61, 157-197.
3. 3. Schepers, L., Van-Veldhoven, P.P., Casteels, M., Eyssen, H.J. & Mannaerts, G.P. (1990) Presence of three acyl-CoA oxidases in rat liver peroxisomes. An inducible fatty acyl-CoA oxidase, a noninducible fatty acyl-CoA oxidase, and a noninducible trihydroxycoprostanoyl-CoA oxidase. J. Biol. Chem. 265, 5242-5246.
4. 4. Varanasi, U., Chu, R., Chu, S., Espinosa, R., LeBeau, M.M. & Reddy, J.K. (1994) Isolation of the human peroxisomal acyl-CoA oxidase gene: organization, promoter analysis, and chromosomal localisation. Proc. Natl Acad. Sci. USA 91, 3107-3111.
5. 5. Baumgart, E., Vanhooren, J.C., Fransen, M., Marynen, P., Puype, M., Vandekerckhove, J., Leunissen, J.A., Fahimi, H.D., Mannaerts, G.P. & van-Veldhoven, P.P. (1996) Molecular characterization of the human peroxisomal branched-chain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger syndrome. Proc. Natl Acad. Sci. USA 93, 13748-13753.
6. 6. Vanhooren, J.C.T., Marynen, P., Mannaerts, G.P. & van Veldhoven, P.P. (1997) Evidence for the existence of a pristanoyl CoA oxidase gene in man. Biochem. J. 325, 593-599.
7. 7. Lazarow, P.B. & De-Duve, C. (1976) A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug. Proc. Natl Acad. Sci. USA 73, 2043-2046.
8. 8. Reddy, J.K. & Mannaerts, G.P. (1994) Peroxisomal lipid metabolism. Annu. Rev. Nutr. 14, 343-370.
9. 9. Flatmark, T., Nilsson, A., Kvannes, J., Eikhom, T.S., Fukami, M.H., Kryvi, H. & Christiansen, E.N. (1988) On the mechanism of induction of the enzyme systems for peroxisomal beta-oxidation of fatty acids in rat liver by diets rich in partially hydrogenated fish oil. Biochim. Biophys. Acta 962, 122-130.
10. 10. Willumsen, N., Hexeberg, S., Skorve, J., Lundquist, M. & Berge, R.K. (1993) Docosahexaenoic acid shows no triglyceride-lowering effects but increases the peroxisomal fatty acid oxidation in liver of rats. J. Lipid Res. 34, 13-22.
11. 11. Orellana, M., Fuentes, O., Rosenbluth, H., Lara, M. & Valdes, E. (1992) Modulation of rat liver peroxisomal and microsomal fatty acid oxidation by starvation. FEBS Lett. 310, 193-196.
12. 12. Thomas, H., Sehadt, L., Knehr, M. & Oesch, F. (1989) Effects of diabetes and starvation on the activity of rat liver epoxide hydrolases, glutathione S-transferases and peroxisomal beta-oxidation. Biochem. Pharmacol. 38, 4291-4297.
13. 13. Tugwood, J.D., Issemann, I., Anderson, R.G., Bundell, K.R., McPheat, W.L. & Green, S. (1992) The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene. EMBO J. 11, 433-439.
14. 14. Varanasi, U., Chu, R., Huang, Q., Castellon, R., Yeldandi, A.V. & Reddy, J.K. (1996) Identification of a peroxisome proliferator-responsive element upstream of the human peroxisomal fatty acyl coenzyme A oxidase gene. J. Biol. Chem. 271, 2147-2155.
15. 15. Latruffe, N. & Vamecq, J. (1997) Peroxisome proliferators and peroxisome proliferator activated receptors (PPARs) as regulators of lipid metabolism. Biochimie 79, 81-94.
16. 16. Braissant, O., Foufelle, F., Scotto, C., Dauca, M. & Wahli, W. (1996) Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 137, 354-366.
17. 17. Vidal-Puig, A., Jimenez-Linan, M., Lowell, B.B., Hamann, A., Hu, E., Spiegelman, B., Flier, J.S. & Moller, D.E. (1996) Regulation of PPAR gamma gene expression by nutrition and obesity in rodents. J. Clin. Invest. 97, 2553-2561.
18. 18. Spiegelman, B.M. & Flier, J.S. (1996) Adipogenesis and obesity: rounding out the big picture. Cell 87, 377-389.
19. 19. Lee, ST., Pineau, T., Drago, J., Lee, E.J., Owens, J.W., Kroetz, D.L., Fernandez-Salguero, P.M., Westphal, H. & Gonzalez, F.J. (1995) Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 15, 3012-3022.
20. 20. Aoyama, T., Peters, J.M., Iritani, N., Nakajima, T., Furihata, K., Hashimoto, T. & Gonzalez, F.J. (1998) Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha). J. Biol. Chem. 273, 5678-5684.
21. 21. MacDonald, R.J., Swift G.H., Pryzbyla, A.E. & Chirgwin, J.M. (1987) Isolation of RNA using guanidinium salts. Methods Enzymol. 152, 219-226.
22. 22. Lehrach, H., Diamond, D., Wozney, J.M. & Boedtker, H. (1977) RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination. Biochemistry 16, 4743-4751.
23. 23. Hasel, K.W. & Sutcliffe, J.G. (1990) Nucleotide sequence of a cDNA coding for mouse cyclophilin. Nucleic Acids Res. 18, 4019.
24. 24. Eferl, R., Lehner, M., Kenner, L., Kapfer, I., Guertl, B. & Zatloukal, K. (1997) Evaluation of different RNA standards for quantitative reverse transcription PCR: possible pitfalls and strategies of avoidance. Trends Genet. Technical Tips online, http://tto.trends.com, T01214.
25. 25. Hoefler, G., Noehammer, C., Levak-Frank, S., El-Shabrawi, Y., Schauer, S., Zechner, R. & Radner, H. (1997) Muscle specific overexpression of human lipoprotein lipase in mice causes increased intracellular free fatty acids and induction of peroxisomal enzymes. Biochimie 79, 163-168.
26. 26. Laemmli, U.K. (1970) Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 227, 680-685.
27. 27. Miyazawa, S., Hayashi, H., Hijikata, M., Ishii, N., Furuta, S., Kagamiyama, H., Osumi, T. & Hashimoto, T. (1987) Complete nucleotide sequence of cDNA and predicted amino acid sequence of rat acyl-CoA oxidase. J. Biol. Chem. 262, 8131-8137.
28. 28. Osumi, T., Ishii, N., Miyazawa, S. & Hashimoto, T. (1987) Isolation and structural characterization of the rat acyl-CoA oxidase gene. J. Biol. Chem. 262, 8138-8143.
29. 29. Pedersen, J.I., Eggertsen, G., Hellman, U., Andersson, U. & Bjorkhem, I. (1997) Molecular cloning and expression of cDNA encoding 3α,7α,12α-trihydrox-5β-cholestanoyl-CoA oxidase from rat liver. J. Biol. Chem. 272, 18481-18589.
30. 30. Baumgart, E., Vanhooren, J.C.T., Fransen, M., Van Leuven, F., Fahimi, H.D., Van-Veldhoven, P.P. & Mannaerts, G.P. (1996) Molecular cloning and further characterization of rat peroxisomal trihydroxycoprostanoyl-CoA oxidase. Biochem. J. 320, 115-121.
31. 31. Okazaki, K., Tan, H., Fukui, S., Kubota, I. & Kamiryo, T. (1987) Peroxisomal acyl-coenzyme A oxidase multigene family of the yeast Candida tropicalis; nucleotide sequence of a third gene and its protein product. Gene 58, 37-44.
32. 32. Gould, S.J., Keller, G.A., Hosken, N., Wilkinson, J. & Subramani, S. (1989) A conserved tripeptide sorts proteins to peroxisomes. J. Cell Biol. 108, 51657-51664.
33. 33. Vanhove, G.F., Van-Veldhoven, P.P., Fransen, M., Denis, S., Eyssen, H.J., Wanders, R.J. & Mannaerts, G.P.J. (1993) The CoA esters of 2-methyl-branched chain fatty acids and of the bile acid intermediates di-and trihydroxycoprostanic acids are oxidized by one single peroxisomal branched chain acyl-CoA oxidase in human liver and kidney. Biol. Chem. 268, 10335-10344.
34. 34. Kvannes, J., Eikhom, T.S. & Flatmark, T. (1994) The peroxisomal beta-oxidation enzyme system of rat heart. Basal level and effect of the peroxisome proliferator clofibrate. Biochim. Biophys. Acta 1201, 203-216.
35. 35. Kvannes, J., Eikhom, T.S. & Flatmark, T. (1995) On the mechanism of stimulation of peroxisomal beta-oxidation in rat heart by partially hydrogenated fish oil. Biochim. Biophys. Acta 1255, 39-49.
36. 36. Lazo, O., Singh, A.K. & Singh, I. (1991) Postnatal development and isolation of peroxisomes from brain. J. Neurochem. 56, 1343-1353.
37. 37. Auestad, N., Korsak, R.A., Morrow, J.W. & Edmond, J. (1991) Fatty acid oxidation and ketogenesis by astrocytes in primary culture. J. Neurochem. 56, 1376-1386.
38. 38. Issemann, I. & Green, S. (1990) Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 347, 645-650.
39. 39. Hoefler, G., Forstner, M., McGuinness, M.C., Hulla, W., Hiden, M., Krisper, P., Kenner, L., Ried, T., Lengauer, C., Zechner, R. et al. (1994) cDNA cloning of the human peroxisomal enoyl-CoA hydratase:3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme and localization to chromosome 3q26.3-3q28: a free left Alu Arm is inserted in the 3′ noncoding region. Genomics 19, 60-67.
40. 40. Quan, F., Korneluk, R.G., Tropak, M.B. & Gravel, R.A. (1986) Isolation and characterization of the human catalase gene. Nucleic Acids Res. 14, 5321-5335.
41. 41. Yeldandi, A.V., Wang, X.D., Alvares, K., Kumar, S., Rao, M.S. & Reddy, J.K. (1990) Human urate oxidase gene: cloning and partial sequence analysis reveal a stop codon within the fifth exon. Biochem. Biophys. Res. Commun. 171, 641-646.
42. 42. Hijikata, M., Wen, J.K., Osumi, T. & Hashimoto, T. (1990) Rat peroxisomal 3-ketoacyl-CoA thiolase gene. Occurrence of two closely related but differentially regulated genes. J. Biol. Chem. 265, 4600-4606.