-
1
-
-
84862777565
-
MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: Results of a network bioinformatics approach
-
Parikh VN, Jin RC, Rabello S, Gulbahce N, White K, Hale A, Cottrill KA, Shaik RS, Waxman AB, Zhang Y-Y, Maron BA, Hartner JC, Fujiwara Y, Orkin SH, Haley KJ, Barabasi A-L, Loscalzo J, Chan SY. MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach. Circulation. 2012;125:1520-1532.
-
(2012)
Circulation
, vol.125
, pp. 1520-1532
-
-
Parikh, V.N.1
Jin, R.C.2
Rabello, S.3
Gulbahce, N.4
White, K.5
Hale, A.6
Cottrill, K.A.7
Shaik, R.S.8
Waxman, A.B.9
Zhang, Y.-Y.10
Maron, B.A.11
Hartner, J.C.12
Fujiwara, Y.13
Orkin, S.H.14
Haley, K.J.15
Barabasi, A.-L.16
Loscalzo, J.17
Chan, S.Y.18
-
2
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 2005;120:15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
3
-
-
77952885217
-
MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function
-
Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC. MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010; 30:1118-1126.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 1118-1126
-
-
Albinsson, S.1
Suarez, Y.2
Skoura, A.3
Offermanns, S.4
Miano, J.M.5
Sessa, W.C.6
-
4
-
-
52949090784
-
Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis
-
Suarez Y, Fernandez-Hernando C, Yu J, Gerber SA, Harrison KD, Pober JS, Iruela-Arispe ML, Merkenschlager M, Sessa WC. Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis. Proc Natl Acad Sci USA. 2008;105:14082-14087.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14082-14087
-
-
Suarez, Y.1
Fernandez-Hernando, C.2
Yu, J.3
Gerber, S.A.4
Harrison, K.D.5
Pober, J.S.6
Iruela-Arispe, M.L.7
Merkenschlager, M.8
Sessa, W.C.9
-
5
-
-
32544438253
-
BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension
-
Aldred MA, Vijayakrishnan J, James V, Soubrier F, Gomez-Sanchez MA, Martensson G, Galie N, Manes A, Corris P, Simonneau G, Humbert M, Morrell NW, Trembath RC. BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension. Hum Mutat. 2006;27:212-213.
-
(2006)
Hum Mutat
, vol.27
, pp. 212-213
-
-
Aldred, M.A.1
Vijayakrishnan, J.2
James, V.3
Soubrier, F.4
Gomez-Sanchez, M.A.5
Martensson, G.6
Galie, N.7
Manes, A.8
Corris, P.9
Simonneau, G.10
Humbert, M.11
Morrell, N.W.12
Trembath, R.C.13
-
6
-
-
33748314526
-
High frequency of BMPR2 exonic deletions/duplications in familial pulmonary arterial hypertension
-
Cogan JD, Pauciulo MW, Batchman AP, Prince MA, Robbins IM, Hedges LK, Stanton KC, Wheeler LA, Phillips JA III, Loyd JE, Nichols WC. High frequency of BMPR2 exonic deletions/duplications in familial pulmonary arterial hypertension. Am J Respir Crit Care Med. 2006;174: 590-598.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 590-598
-
-
Cogan, J.D.1
Pauciulo, M.W.2
Batchman, A.P.3
Prince, M.A.4
Robbins, I.M.5
Hedges, L.K.6
Stanton, K.C.7
Wheeler, L.A.8
Phillips Iii, J.A.9
Loyd, J.E.10
Nichols, W.C.11
-
7
-
-
0035163071
-
BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension
-
Machado RD, Pauciulo MW, Thomson JR, Lane KB, Morgan NV, Wheeler L, Phillips JA, III, Newman J, Williams D, Galie N, Manes A, McNeil K, Yacoub M, Mikhail G, Rogers P, Corris P, Humbert M, Donnai D, Martensson G, Tranebjaerg L, Loyd JE, Trembath RC, Nichols WC. BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension. Am J Hum Genet. 2001;68:92-102.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 92-102
-
-
MacHado, R.D.1
Pauciulo, M.W.2
Thomson, J.R.3
Lane, K.B.4
Morgan, N.V.5
Wheeler, L.6
Phillips Iii, J.A.7
Newman, J.8
Williams, D.9
Galie, N.10
Manes, A.11
McNeil, K.12
Yacoub, M.13
Mikhail, G.14
Rogers, P.15
Corris, P.16
Humbert, M.17
Donnai, D.18
Martensson, G.19
Tranebjaerg, L.20
Loyd, J.E.21
Trembath, R.C.22
Nichols, W.C.23
more..
-
8
-
-
32544458797
-
Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension
-
Machado RD, Aldred MA, James V, Harrison RE, Patel B, Schwalbe EC, Gruenig E, Janssen B, Koehler R, Seeger W, Eickelberg O, Olschewski H, Elliott CG, Glissmeyer E, Carlquist J, Kim M, Torbicki A, Fijalkowska A, Szewczyk G, Parma J, Abramowicz MJ, Galie N, Morisaki H, Kyotani S, Nakanishi N, Morisaki T, Humbert M, Simonneau G, Sitbon O, Soubrier F, Coulet F, Morrell NW, Trembath RC. Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension. Hum Mutat. 2006;27:121-132.
-
(2006)
Hum Mutat
, vol.27
, pp. 121-132
-
-
MacHado, R.D.1
Aldred, M.A.2
James, V.3
Harrison, R.E.4
Patel, B.5
Schwalbe, E.C.6
Gruenig, E.7
Janssen, B.8
Koehler, R.9
Seeger, W.10
Eickelberg, O.11
Olschewski, H.12
Elliott, C.G.13
Glissmeyer, E.14
Carlquist, J.15
Kim, M.16
Torbicki, A.17
Fijalkowska, A.18
Szewczyk, G.19
Parma, J.20
Abramowicz, M.J.21
Galie, N.22
Morisaki, H.23
Kyotani, S.24
Nakanishi, N.25
Morisaki, T.26
Humbert, M.27
Simonneau, G.28
Sitbon, O.29
Soubrier, F.30
Coulet, F.31
Morrell, N.W.32
Trembath, R.C.33
more..
-
9
-
-
8644256840
-
BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia
-
Beppu H, Ichinose F, Kawai N, Jones RC, Yu PB, Zapol WM, Miyazono K, Li E, Bloch KD. BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia. Am J Physiol Lung Cell Mol Physiol. 2004;287: L1241-L1247.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Beppu, H.1
Ichinose, F.2
Kawai, N.3
Jones, R.C.4
Yu, P.B.5
Zapol, W.M.6
Miyazono, K.7
Li, E.8
Bloch, K.D.9
-
10
-
-
23044504042
-
Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice
-
Song Y, Jones JE, Beppu H, Keaney JF Jr, Loscalzo J, Zhang YY. Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice. Circulation. 2005;112:553-562.
-
(2005)
Circulation
, vol.112
, pp. 553-562
-
-
Song, Y.1
Jones, J.E.2
Beppu, H.3
Keaney Jr., J.F.4
Loscalzo, J.5
Zhang, Y.Y.6
-
11
-
-
33645751955
-
Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice
-
Long L, MacLean MR, Jeffery TK, Morecroft I, Yang X, Rudarakanchana N, Southwood M, James V, Trembath RC, Morrell NW. Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice. Circ Res. 2006;98:818-827.
-
(2006)
Circ Res
, vol.98
, pp. 818-827
-
-
Long, L.1
MacLean, M.R.2
Jeffery, T.K.3
Morecroft, I.4
Yang, X.5
Rudarakanchana, N.6
Southwood, M.7
James, V.8
Trembath, R.C.9
Morrell, N.W.10
-
12
-
-
2342486700
-
Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle
-
West J, Fagan K, Steudel W, Fouty B, Lane K, Harral J, Hoedt-Miller M, Tada Y, Ozimek J, Tuder R, Rodman DM. Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle. Circ Res. 2004;94:1109-1114.
-
(2004)
Circ Res
, vol.94
, pp. 1109-1114
-
-
West, J.1
Fagan, K.2
Steudel, W.3
Fouty, B.4
Lane, K.5
Harral, J.6
Hoedt-Miller, M.7
Tada, Y.8
Ozimek, J.9
Tuder, R.10
Rodman, D.M.11
-
13
-
-
34250172419
-
MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation
-
Ji R, Cheng Y, Yue J, Yang J, Liu X, Chen H, Dean DB, Zhang C. MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation. Circ Res. 2007;100:1579-1588.
-
(2007)
Circ Res
, vol.100
, pp. 1579-1588
-
-
Ji, R.1
Cheng, Y.2
Yue, J.3
Yang, J.4
Liu, X.5
Chen, H.6
Dean, D.B.7
Zhang, C.8
-
14
-
-
46449128469
-
SMAD proteins control DROSHA-mediated microRNA maturation
-
Davis BN, Hilyard AC, Lagna G, Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature. 2008;454:56-61.
-
(2008)
Nature
, vol.454
, pp. 56-61
-
-
Davis, B.N.1
Hilyard, A.C.2
Lagna, G.3
Hata, A.4
-
15
-
-
79959973595
-
MicroRNA-21 targets peroxisome proliferators-activated receptor-alpha in an autoregulatory loop to modulate flow-induced endothelial inflammation
-
Zhou J, Wang KC, Wu W, Subramaniam S, Shyy JY, Chiu JJ, Li JY, Chien S. MicroRNA-21 targets peroxisome proliferators-activated receptor-alpha in an autoregulatory loop to modulate flow-induced endothelial inflammation. Proc Natl Acad Sci USA. 2011;108:10355-10360.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 10355-10360
-
-
Zhou, J.1
Wang, K.C.2
Wu, W.3
Subramaniam, S.4
Shyy, J.Y.5
Chiu, J.J.6
Li, J.Y.7
Chien, S.8
-
16
-
-
77955373730
-
MiR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
-
Liu G, Friggeri A, Yang Y, Milosevic J, Ding Q, Thannickal VJ, Kaminski N, Abraham E. miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis. J Exp Med. 2010;207:1589-1597.
-
(2010)
J Exp Med
, vol.207
, pp. 1589-1597
-
-
Liu, G.1
Friggeri, A.2
Yang, Y.3
Milosevic, J.4
Ding, Q.5
Thannickal, V.J.6
Kaminski, N.7
Abraham, E.8
-
17
-
-
52449100144
-
Role of microRNAs in vascular diseases, inflammation, and angiogenesis
-
Urbich C, Kuehbacher A, Dimmeler S. Role of microRNAs in vascular diseases, inflammation, and angiogenesis. Cardiovasc Res. 2008;79: 581-588.
-
(2008)
Cardiovasc Res
, vol.79
, pp. 581-588
-
-
Urbich, C.1
Kuehbacher, A.2
Dimmeler, S.3
-
18
-
-
79952733132
-
Role for miR-204 in human pulmonary arterial hypertension
-
Courboulin A, Paulin R, Giguere NJ, Saksouk N, Perreault T, Meloche J, Paquet ER, Biardel S, Provencher S, Cote J, Simard MJ, Bonnet S. Role for miR-204 in human pulmonary arterial hypertension. J Exp Med. 2011;208:535-548.
-
(2011)
J Exp Med
, vol.208
, pp. 535-548
-
-
Courboulin, A.1
Paulin, R.2
Giguere, N.J.3
Saksouk, N.4
Perreault, T.5
Meloche, J.6
Paquet, E.R.7
Biardel, S.8
Provencher, S.9
Cote, J.10
Simard, M.J.11
Bonnet, S.12
-
19
-
-
84876051299
-
Unraveling the mystery of cancer by secretory microRNA: Horizontal microRNA transfer between living cells
-
Kosaka N, Ochiya T. Unraveling the mystery of cancer by secretory microRNA: horizontal microRNA transfer between living cells. Front Genet. 2011;2:97.
-
(2011)
Front Genet
, vol.2
, pp. 97
-
-
Kosaka, N.1
Ochiya, T.2
-
20
-
-
79960230895
-
Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data
-
Zhang C, Darnell RB. Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data. Nat Biotechnol. 2011;29:607-614.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 607-614
-
-
Zhang, C.1
Darnell, R.B.2
|