메뉴 건너뛰기




Volumn 26, Issue 4, 2012, Pages 319-335

Beneficial and adverse psychotropic effects of antiepileptic drugs in patients with epilepsy: A summary of prevalence, underlying mechanisms and data limitations

Author keywords

Aggression; Antiepileptic drugs; Anxiety; Depression; Epilepsy; Psychotic disorders; Sleep.

Indexed keywords

ANTICONVULSIVE AGENT; BENZODIAZEPINE; CARBAMAZEPINE; CARISBAMATE; DIAZEPAM; ETIRACETAM; FELBAMATE; GABAPENTIN; HARKOSERIDE; LAMOTRIGINE; LORECLEZOLE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PREGABALIN; PRIMIDONE; TIAGABINE; TOPIRAMATE; VALPROIC ACID; VIGABATRIN; ZONISAMIDE;

EID: 84859063328     PISSN: 11727047     EISSN: 11791934     Source Type: Journal    
DOI: 10.2165/11599780-000000000-00000     Document Type: Review
Times cited : (111)

References (115)
  • 2
    • 33747049831 scopus 로고    scopus 로고
    • Diverse mechanisms of antiepileptic drugs in the development pipeline
    • DOI 10.1016/j.eplepsyres.2006.02.004, PII S0920121106000635
    • Rogawski MA. Diverse mechanisms of antiepileptic drugs in the development pipeline. Epilepsy Res 2006; 69 (3): 273-94 (Pubitemid 44209049)
    • (2006) Epilepsy Research , vol.69 , Issue.3 , pp. 273-294
    • Rogawski, M.A.1
  • 7
    • 34447344551 scopus 로고    scopus 로고
    • Efficacy and safety of oral lacosamide as adjunctive therapy in adults with partial-onset seizures
    • DOI 10.1111/j.1528-1167.2007.01188.x
    • Ben-Menachem E, Biton V, Jatuzis D, et al. Efficacy and safety of oral lacosamide as adjunctive therapy in adults with partial-onset seizures. Epilepsia 2007; 48 (7): 1308-17 (Pubitemid 47063096)
    • (2007) Epilepsia , vol.48 , Issue.7 , pp. 1308-1317
    • Ben-Menachem, E.1    Biton, V.2    Jatuzis, D.3    Abou-Khalil, B.4    Doty, P.5    Rudd, G.D.6
  • 8
    • 61849088333 scopus 로고    scopus 로고
    • Adjunctive lacosamide for partial-onset seizures: Efficacy and safety results from a randomized controlled trial
    • Halász P, Kälviäinen R, Mazurkiewicz-Beldzińska M, et al. Adjunctive lacosamide for partial-onset seizures: efficacy and safety results from a randomized controlled trial. Epilepsia 2009; 50 (3): 443-53
    • (2009) Epilepsia , vol.50 , Issue.3 , pp. 443-453
    • Halász, P.1    Kälviäinen, R.2    Mazurkiewicz-Beldzińska, M.3
  • 9
    • 0002611151 scopus 로고    scopus 로고
    • Disorders of thought and volition: Schizophrenia
    • Kandel ER, Schwartz JH, Jessell TM, editors. 4th ed. New York (NY): McGraw-Hill
    • Kandel ER. Disorders of thought and volition: schizophrenia. In: Kandel ER, Schwartz JH, Jessell TM, editors. Principles of neural science. 4th ed. New York (NY): McGraw-Hill, 2000; 60: 1188-208
    • (2000) Principles of Neural Science , vol.60 , pp. 1188-1208
    • Kandel, E.R.1
  • 10
    • 84859046682 scopus 로고    scopus 로고
    • Basic psychiatric concepts
    • Richards D, Clark T, Clarke C, editors. New York (NY): Oxford University Press
    • Oyebode F, Clark T. Basic psychiatric concepts. In: Richards D, Clark T, Clarke C, editors. The human brain and its disorders. New York (NY): Oxford University Press, 2007; 4: 62-83
    • (2007) The Human Brain and Its Disorders , vol.4 , pp. 62-83
    • Oyebode, F.1    Clark, T.2
  • 11
    • 0004235298 scopus 로고
    • American Psychiatric Association. 4th ed. Washington, DC: American Psychiatric Association
    • American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. Washington, DC: American Psychiatric Association, 1994
    • (1994) Diagnostic and Statistical Manual of Mental Disorders
  • 13
    • 0036816667 scopus 로고    scopus 로고
    • Treatment of depressive disorders in epilepsy
    • Gilliam F, Kanner AM. Treatment of depressive disorders in epilepsy. Epilepsy Behav 2002; 3 (5 Suppl. 1): S2-9
    • (2002) Epilepsy Behav , vol.3 , Issue.5 SUPPL. 1
    • Gilliam, F.1    Kanner, A.M.2
  • 14
    • 68049122102 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • Prisma Group
    • Moher D, Liberati A, Tetzlaff J, et al., Prisma Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 2009; 6 (7): e1000097
    • (2009) PLoS Med , vol.6 , Issue.7
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3
  • 15
    • 0034950048 scopus 로고    scopus 로고
    • Behavioural effects of new anticonvulsants
    • Besag FM. Behavioural effects of new anticonvulsants. Drug Saf 2001; 24 (7): 513-36
    • (2001) Drug Saf , vol.24 , Issue.7 , pp. 513-536
    • Besag, F.M.1
  • 16
    • 0024494368 scopus 로고
    • A double-blind study comparing oxcarbazepine and carbamazepine in patients with newly diagnosed, previously untreated epilepsy
    • DOI 10.1016/0920-1211(89)90070-3
    • Dam M, Ekberg R, Løyning Y, et al., Scandinavian Oxcarbazepine Study Group. A double-blind study comparing oxcarbazepine and carbamazepine in patients with newly diagnosed, previously untreated epilepsy. Epilepsy Res 1989; 3: 70-6 (Pubitemid 19009372)
    • (1989) Epilepsy Research , vol.3 , Issue.1 , pp. 70-76
    • Dam, M.1    Ekberg, R.2    Loyning, Y.3    Waltimo, O.4    Jakobsen, K.5
  • 17
    • 0027536904 scopus 로고
    • Psychiatric aspects of epilepsy in childhood treated with carbamazepine phenytoin or sodium valproate: A random trial
    • Berg I, Butler A, Ellis M, et al. Psychiatric aspects of epilepsy in childhood treated with carbamazepine, phenytoin or sodium valproate: a random trial. Dev Med Child Neurol 1993; 35: 149-57 (Pubitemid 23059555)
    • (1993) Developmental Medicine and Child Neurology , vol.35 , Issue.2 , pp. 149-157
    • Berg, I.1    Butler, A.2    Ellis, M.3    Foster, J.4
  • 18
    • 0029651761 scopus 로고
    • Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy: UK Lamotrigine/Carbamazepine Monotherapy Trial Group
    • Brodie MJ, Richens A, Yuen AWC. Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy: UK Lamotrigine/Carbamazepine Monotherapy Trial Group. Lancet 1995; 345: 476-9
    • (1995) Lancet , vol.345 , pp. 476-479
    • Brodie, M.J.1    Richens, A.2    Yuen, A.W.C.3
  • 19
    • 0028856918 scopus 로고
    • Comparing the cognitive effects of phenytoin and carbamazepine in long-term monotherapy: A two year follow up
    • Pulliainen V, Jokelainen M. Comparing the cognitive effects of phenytoin and carbamazepine in long-term monotherapy: a two year follow up. Epilepsia 1995; 36: 1195-202
    • (1995) Epilepsia , vol.36 , pp. 1195-1202
    • Pulliainen, V.1    Jokelainen, M.2
  • 20
    • 0033519964 scopus 로고    scopus 로고
    • Safety and efficacy of vigabatrin and carbamazepine in newly diagnosed epilepsy: A multicentre randomised double-blind study
    • DOI 10.1016/S0140-6736(98)10531-7
    • Chadwick D. Safety and efficacy of vigabatrin and carbamazepine in newly diagnosed epilepsy: a multicentre randomised double-blind study. Lancet 1999; 354: 13-9 (Pubitemid 29304296)
    • (1999) Lancet , vol.354 , Issue.9172 , pp. 13-19
    • Chadwick, D.1
  • 23
    • 0032910512 scopus 로고
    • Rectal diazepam gel for treatment of acute repetitive seizures
    • Kriel RL, Cloyd JC, Pellock JM, et al. Rectal diazepam gel for treatment of acute repetitive seizures. Pediatr Neurol 1990; 20: 282-8
    • (1990) Pediatr Neurol , vol.20 , pp. 282-288
    • Kriel, R.L.1    Cloyd, J.C.2    Pellock, J.M.3
  • 25
    • 33846357448 scopus 로고    scopus 로고
    • Psychiatric and behavioral side effects of the newer antiepileptic drugs in adults with epilepsy
    • DOI 10.1016/j.yebeh.2006.08.008, PII S1525505006003246
    • Weintraub D, Buchsbaum R, Resor Jr SR, et al. Psychiatric and behavioural side effects of the newer antiepileptic drugs in adults with epilepsy. Epilepsy Behav 2007; 10: 105-10 (Pubitemid 46132156)
    • (2007) Epilepsy and Behavior , vol.10 , Issue.1 , pp. 105-110
    • Weintraub, D.1    Buchsbaum, R.2    Resor Jr., S.R.3    Hirsch, L.J.4
  • 30
    • 39749167069 scopus 로고    scopus 로고
    • Intravenous lacosamide as replacement for oral lacosamide in patients with partial-onset seizures
    • DOI 10.1111/j.1528-1167.2007.01317.x
    • Biton V, Rosenfeld WE, Whitesides J, et al. Intravenous lacosamide as replacement for oral lacosamide in patients with partial-onset seizures. Epilepsia 2008; 49 (3): 418-24 (Pubitemid 351294527)
    • (2008) Epilepsia , vol.49 , Issue.3 , pp. 418-424
    • Biton, V.1    Rosenfeld, W.E.2    Whitesides, J.3    Fountain, N.B.4    Vaiciene, N.5    Rudd, G.D.6
  • 32
    • 0032963219 scopus 로고    scopus 로고
    • Lamotrigine associated with insomnia
    • Sadler M. Lamotrigine associated with insomnia. Epilepsia 1999; 40 (3): 322-5 (Pubitemid 29164797)
    • (1999) Epilepsia , vol.40 , Issue.3 , pp. 322-325
    • Sadler, M.1
  • 33
    • 0033767336 scopus 로고    scopus 로고
    • Add-on lamotrigine treatment in children and young adults with severe partial epilepsy: An open, prospective, long-term study
    • Parmeggiani L, Belmonte A, Ferrarri AR, et al. Add-on lamotrigine treatment in children and young adults with severe partial epilepsy: an open, prospective, long-term study. J Child Neurol 2000; 15: 671-4
    • (2000) J Child Neurol , vol.15 , pp. 671-674
    • Parmeggiani, L.1    Belmonte, A.2    Ferrarri, A.R.3
  • 34
    • 0002060457 scopus 로고    scopus 로고
    • Lamotrigine Monotherapy Improves Depressive Symptoms in Epilepsy: A Double-Blind Comparison with Valproate
    • DOI 10.1006/ebeh.2000.0143, PII S1525505000901434
    • Edwards KR, Sackellares JC, Vuong A, et al. Lamotrigine monotherapy improves depressive symptoms in epilepsy: a double-blind comparison with valproate. Epilepsy Behav 2001; 2: 28-36 (Pubitemid 33585768)
    • (2001) Epilepsy and Behavior , vol.2 , Issue.1 , pp. 28-36
    • Edwards, K.R.1    Sackellares, J.C.2    Vuong, A.3    Hammer, A.E.4    Barrett, P.S.5
  • 35
    • 0037305116 scopus 로고    scopus 로고
    • Lamotrigine versus valproate monotherapy-associated weight change in adolescents with epilepsy: Results from a post hoc analysis of a randomized, double-blind clinical trial
    • Biton V, Levisohn P, Hoyler S, et al. Lamotrigine versus valproate monotherapy-associated weight change in adolescents with epilepsy: results from a post hoc analysis of a randomized, double-blind clinical trial. J Child Neurol 2003; 18: 133-9 (Pubitemid 36432344)
    • (2003) Journal of Child Neurology , vol.18 , Issue.2 , pp. 133-139
    • Biton, V.1
  • 36
    • 1842788120 scopus 로고    scopus 로고
    • Quality of life improvement with conversion to lamotrigine monotherapy
    • DOI 10.1016/j.yebeh.2003.11.031
    • Cramer JA, Hammer AE, Kustra RP. Quality of life improvement with conversion to lamotrigine monotherapy. Epilepsy Behav 2004; 5: 224-30 (Pubitemid 38461212)
    • (2004) Epilepsy and Behavior , vol.5 , Issue.2 , pp. 224-230
    • Cramer, J.A.1    Hammer, A.E.2    Kustra, R.P.3
  • 37
    • 15344344623 scopus 로고    scopus 로고
    • Improved mood states with lamotrigine in patients with epilepsy
    • DOI 10.1016/j.yebeh.2004.07.005, PII S1525505004002264
    • Cramer JA, Hammer AE, Kustra RP. Improved mood states with lamotrigine in patients with epilepsy. Epilepsy Behav 2004; 5: 702-7 (Pubitemid 40392587)
    • (2004) Epilepsy and Behavior , vol.5 , Issue.5 , pp. 702-707
    • Cramer, J.A.1    Hammer, A.E.2    Kustra, R.P.3
  • 38
    • 33846401117 scopus 로고    scopus 로고
    • Effect of lamotrigine on depressive symptoms in adult patients with epilepsy
    • DOI 10.1016/j.yebeh.2006.09.008, PII S1525505006003544
    • Ettinger AB, Kustra RP, Hammer AE. Effect of lamotrigine on depressive symptoms in adult patients with epilepsy. Epilepsy Behav 2007; 10: 148-54 (Pubitemid 46132163)
    • (2007) Epilepsy and Behavior , vol.10 , Issue.1 , pp. 148-154
    • Ettinger, A.B.1    Kustra, R.P.2    Hammer, A.E.3
  • 39
    • 54549087872 scopus 로고    scopus 로고
    • Effects of lamotrigine on mood in older adults with epilepsy and comorbid depressive symptoms: An open-label, multicentre, prospective study
    • Fakhoury TA, Miller JM, Hammer AE, et al. Effects of lamotrigine on mood in older adults with epilepsy and comorbid depressive symptoms: an open-label, multicentre, prospective study. Drugs Aging 2008; 25 (11): 955-62
    • (2008) Drugs Aging , vol.25 , Issue.11 , pp. 955-962
    • Fakhoury, T.A.1    Miller, J.M.2    Hammer, A.E.3
  • 40
    • 0042386034 scopus 로고    scopus 로고
    • Improvement in depression associated with partial epilepsy in patients treated with lamotrigine
    • DOI 10.1016/S1525-5050(02)00528-0, PII S1525505002005280
    • Kalogjera-Sackellares D, Sackellares JC. Improvement in depression associated with partial epilepsy in patients treated with lamotrigine. Epilepsy Behav 2002; 3: 510-6 (Pubitemid 37098511)
    • (2002) Epilepsy and Behavior , vol.3 , Issue.6 , pp. 510-516
    • Kalogjera-Sackellares, D.1    Sackellares, J.C.2
  • 41
    • 61849184228 scopus 로고    scopus 로고
    • Effects of lamotrigine compared with levetiracetam on anger, hostility and total mood in patients with partial epilepsy
    • Labiner DM, Ettinger AB, Fakhoury TA, et al. Effects of lamotrigine compared with levetiracetam on anger, hostility and total mood in patients with partial epilepsy. Epilepsia 2009; 50 (3): 434-42
    • (2009) Epilepsia , vol.50 , Issue.3 , pp. 434-442
    • Labiner, D.M.1    Ettinger, A.B.2    Fakhoury, T.A.3
  • 42
    • 80052967975 scopus 로고    scopus 로고
    • Efficacy and safety of pregabalin in patients with newly diagnosed partial seizures: A phase 3, double-blind, randomised, parallel-group trial
    • Kwan P, Brodie MJ, Kälviänen R, et al. Efficacy and safety of pregabalin in patients with newly diagnosed partial seizures: a phase 3, double-blind, randomised, parallel-group trial. Lancet Neurol 2011; 10: 881-90
    • (2011) Lancet Neurol , vol.10 , pp. 881-890
    • Kwan, P.1    Brodie, M.J.2    Kälviänen, R.3
  • 44
    • 0037387847 scopus 로고    scopus 로고
    • Efficacy and tolerability of levetiracetam during 1-year follow-up in patients with refractory epilepsy
    • DOI 10.1016/S1059-1311(02)00251-0
    • Ben-Menachem E, Gilland E. Efficacy and tolerability of levetiracetam during 1-year follow-up in patients with refractory epilepsy. Seizure 2003; 12: 131-5 (Pubitemid 36443006)
    • (2003) Seizure , vol.12 , Issue.3 , pp. 131-135
    • Ben-Menachem, E.1    Gilland, E.2
  • 45
    • 0037390579 scopus 로고    scopus 로고
    • Clinical experience of marketed levetiracetam in an epilepsy clinic - A one year follow up study
    • DOI 10.1016/S1059-1311(02)00258-3
    • Betts T, Yarrow H, Greenhill L, et al. Clinical experience of marketed levetiracetam in an epilepsy clinic: a one year follow up study. Seizure 2003; 12: 136-40 (Pubitemid 36443007)
    • (2003) Seizure , vol.12 , Issue.3 , pp. 136-140
    • Betts, T.1    Yarrow, H.2    Greenhill, L.3    Barrett, M.4
  • 46
    • 0038644777 scopus 로고    scopus 로고
    • A systematic review of the behavioral effects of levetiracetam in adults with epilepsy, cognitive disorders, or an anxiety disorder during clinical trials
    • Cramer JA, de Rue K, Devisnky O, et al. A systematic review of the behavioral effects of levetiracetam in adults with epilepsy, cognitive disorders, or an anxiety disorder during clinical trials. Epilepsy Behav 2003; 4: 123-32
    • (2003) Epilepsy Behav , vol.4 , pp. 123-132
    • Cramer, J.A.1    De Rue, K.2    Devisnky, O.3
  • 48
    • 0942287940 scopus 로고    scopus 로고
    • Psychiatric adverse events in patients with epilepsy and learning disabilities taking levetiracetam
    • DOI 10.1016/S1059-1311(03)00111-0
    • Mula M, Trimbl MR, Sander JWAS. Psychiatric adverse events in patients with epilepsy and learning disabilities taking levetiracetam. Seizure 2004; 13: 55-7 (Pubitemid 38139666)
    • (2004) Seizure , vol.13 , Issue.1 , pp. 55-57
    • Mula, M.1    Trimble, M.R.2    Sander, J.W.A.S.3
  • 50
    • 38749108890 scopus 로고    scopus 로고
    • Effect of levetiracetam on depression and anxiety in adult epileptic patients
    • Mazza M, Martini A, Scoppetta M, et al. Effect of levetiracetam on depression and anxiety in adult epileptic patients. Prog Neuropsychopharmacol Biol Psychiatry 2007; 32: 539-43
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.32 , pp. 539-543
    • Mazza, M.1    Martini, A.2    Scoppetta, M.3
  • 51
    • 77954383071 scopus 로고    scopus 로고
    • Assessment of behavioural and emotional functioning using standardized instruments in children and adolescents with partialonset seizures treated with adjunctive levetiracetam in a randomized, placebo-controlled trial
    • de la Loge C, Hunter SJ, Schiemann J, et al. Assessment of behavioural and emotional functioning using standardized instruments in children and adolescents with partialonset seizures treated with adjunctive levetiracetam in a randomized, placebo-controlled trial. Epilepsy Behav 2010; 18: 291-8
    • (2010) Epilepsy Behav , vol.18 , pp. 291-298
    • De La Loge, C.1    Hunter, S.J.2    Schiemann, J.3
  • 52
    • 70350417839 scopus 로고    scopus 로고
    • Neurocognitive effects of adjunctive levetiracetam in children with partial-onset seizures: A randomized, double-blind, placebo-controlled, noninferiority trial
    • N01103 Levetiracetam Study Group
    • Levisohn PM, Mintz M, Hunter SJ, et al., N01103 Levetiracetam Study Group. Neurocognitive effects of adjunctive levetiracetam in children with partial-onset seizures: a randomized, double-blind, placebo-controlled, noninferiority trial. Epilepsia 2009; 50 (11): 2377-89
    • (2009) Epilepsia , vol.50 , Issue.11 , pp. 2377-2389
    • Levisohn, P.M.1    Mintz, M.2    Hunter, S.J.3
  • 53
    • 0025817389 scopus 로고
    • A double-blind, placebo-controlled evaluation of the efficacy and safety of loreclezole as add-on therapy in patients with uncontrolled partial seizures
    • Rentmeester T, Janssen A, Hulsman J, et al. A double-blind, placebo-controlled evaluation of the efficacy and safety of loreclezole as add-on therapy in patients with uncontrolled partial seizures. Epilepsy Res 1991; 9: 59-69
    • (1991) Epilepsy Res , vol.9 , pp. 59-69
    • Rentmeester, T.1    Janssen, A.2    Hulsman, J.3
  • 57
    • 0030017195 scopus 로고    scopus 로고
    • Comparison of phenobarbitone, phenytoin with sodium valproate: Randomized, double-blind study
    • Thilothammal N, Banu K, Ratnam RS. Comparison of phenobarbitone, phenytoin with sodium valproate: randomized, double-blind study. Indian Pediatr 1996; 33 (7): 549-55 (Pubitemid 26245861)
    • (1996) Indian Pediatrics , vol.33 , Issue.7 , pp. 549-555
    • Thilothammal, N.1    Banu, K.2    Ratnam, R.S.3
  • 59
    • 18844481370 scopus 로고    scopus 로고
    • Psychiatric symptoms after therapy with new antiepileptic drugs: Psychopathological and seizure related variables
    • DOI 10.1053/seiz.2000.0405
    • Trimble MR, Rüsch N, Betts T, et al. Psychiatric symptoms after therapy with new antiepileptic drugs: psychopathological and seizure related variables. Seizure 2000; 9: 249-54 (Pubitemid 30427132)
    • (2000) Seizure , vol.9 , Issue.4 , pp. 249-254
    • Trimble, M.R.1    Rusch, N.2    Betts, T.3    Crawford, P.M.4
  • 60
    • 0036218394 scopus 로고    scopus 로고
    • Occurrence of psychosis in patients with epilepsy randomized to tiagabine or placebo treatment
    • DOI 10.1046/j.1528-1157.2002.16000.x
    • Sackellares JC, Krauss G, Sommerville KW, et al. Occurrence of psychosis in patients with epilepsy randomized to tiagabine or placebo treatment. Epilepsia 2002; 43 (4): 394-8 (Pubitemid 34297177)
    • (2002) Epilepsia , vol.43 , Issue.4 , pp. 394-398
    • Sackellares, J.C.1    Krauss, G.2    Sommerville, K.W.3    Deaton, R.4
  • 61
    • 0033594350 scopus 로고    scopus 로고
    • A double-blind randomized trial of topiramate as adjunctive therapy for partial-onset seizures in children
    • Elterman RD, Glauser TA, Wylie E, et al. A double-blind, randomised trial of topiramate as adjunctive therapy for partial-onset seizures in children: Topiramate YP Study Group. Neurology 1999; 52 (7): 1338-44 (Pubitemid 29190521)
    • (1999) Neurology , vol.52 , Issue.7 , pp. 1338-1344
    • Elterman, R.D.1    Glauser, T.A.2    Wyllie, E.3    Reife, R.4    Wu, S.-C.5    Pledger, G.6
  • 62
    • 0033150169 scopus 로고    scopus 로고
    • Acute psychotic symptoms induced by topiramate
    • DOI 10.1053/seiz.1999.0287
    • Khan A, Fraught E, Gilliam F, et al. Acute psychotic symptoms induced by topiramate. Seizure 1999; 8: 235-7 (Pubitemid 29401589)
    • (1999) Seizure , vol.8 , Issue.4 , pp. 235-237
    • Khan, A.1    Faught, E.2    Gilliam, F.3    Kuzniecky, R.4
  • 63
    • 0032976081 scopus 로고    scopus 로고
    • A double-blind, randomized trial of topiramate in Lennox-Gastaut syndrome
    • Sachdeo RC, Glauser TA, Ritter F, et al. A double-blind, randomized trial of topiramate in Lennox-Gastaut syndrome: Topiramate YL Study Group. Neurology 1999; 52 (9): 1882-7 (Pubitemid 29260904)
    • (1999) Neurology , vol.52 , Issue.9 , pp. 1882-1887
    • Sachdeo, R.C.1    Glauser, T.A.2    Ritter, F.3    Reife, R.4    Lim, P.5    Pledger, G.6
  • 64
    • 0033816145 scopus 로고    scopus 로고
    • A multicenter, randomized clinical study to evaluate the effect on cognitive function of topiramate compared with valproate as add-on therapy to carbamazepine in patients with partial-onset seizures
    • Aldenkamp AP, Baker G, Mulder OG, et al. A multicenter, randomized clinical study to evaluate the effect on cognitive function of topiramate compared with valproate as add-on therapy to carbamazepine in patients with partial-onset seizures. Epilepsia 2000; 41 (9): 1167-78
    • (2000) Epilepsia , vol.41 , Issue.9 , pp. 1167-1178
    • Aldenkamp, A.P.1    Baker, G.2    Mulder, O.G.3
  • 65
    • 0036785082 scopus 로고    scopus 로고
    • Low-dose topiramate in adults with treatment-resistant partial-onset seizures
    • EPAJ-119 Study Group
    • Guberman A, Neto W, Gassmann-Mayer C, EPAJ-119 Study Group. Low-dose topiramate in adults with treatment-resistant partial-onset seizures. Acta Neurol Scand 2002; 106: 183-9
    • (2002) Acta Neurol Scand , vol.106 , pp. 183-189
    • Guberman, A.1    Neto, W.2    Gassmann-Mayer, C.3
  • 66
    • 0242494505 scopus 로고    scopus 로고
    • Randomized, concentration-controlled trial of topiramate in refractory focal epilepsy
    • Christensen J, Andreasen F, Poulsen JH, et al. Randomized, concentration-controlled trial of topiramate in refractory focal epilepsy. Neurology 2003; 61: 1210-8 (Pubitemid 37377539)
    • (2003) Neurology , vol.61 , Issue.9 , pp. 1210-1218
    • Christensen, J.1    Andreasen, F.2    Poulsen, J.H.3    Dam, M.4
  • 67
    • 10744230559 scopus 로고    scopus 로고
    • A past psychiatric history may be a risk factor for topiramate-related psychiatric and cognitive adverse events
    • Kanner AM, Wuu J, Faught E, et al. A past psychiatric history may be a risk factor for topiramate-related psychiatric and cognitive adverse events. Epilepsy Behav 2003; 4: 548-52
    • (2003) Epilepsy Behav , vol.4 , pp. 548-552
    • Kanner, A.M.1    Wuu, J.2    Faught, E.3
  • 68
    • 0037989698 scopus 로고    scopus 로고
    • Topiramate and psychiatric adverse events in patients with epilepsy
    • Mula M, Trimble MR, Lhatoo SD, et al. Topiramate and psychiatric adverse events in patients with epilepsy. Epilepsia 2003; 44: 659-93
    • (2003) Epilepsia , vol.44 , pp. 659-693
    • Mula, M.1    Trimble, M.R.2    Lhatoo, S.D.3
  • 70
    • 0016755244 scopus 로고
    • Controlled trial of sodium valproate in severe epilepsy
    • Richens A, Ahmad S. Controlled trial of sodium valproate in severe epilepsy. Br Med J 1975; 4: 255-6
    • (1975) Br Med J , vol.4 , pp. 255-256
    • Richens, A.1    Ahmad, S.2
  • 71
    • 0028888579 scopus 로고
    • Effects of differing dosages of vigabatrin (Sabril) on cognitive abilities and quality of life in epilepsy
    • Dodrill CB, Arnett JL, Sommerville KW, et al. Effects of differing dosages of vigabatrin (Sabril) on cognitive abilities and quality of life in epilepsy. Epilepsia 1995; 36: 164-73
    • (1995) Epilepsia , vol.36 , pp. 164-173
    • Dodrill, C.B.1    Arnett, J.L.2    Sommerville, K.W.3
  • 72
    • 0029094094 scopus 로고
    • Retrospective study of vigabatrin and psychiatric behavioural disturbances
    • Wong I. Retrospective study of vigabatrin and psychiatric behavioural disturbances. Epilepsy Res 1995; 21: 227-30
    • (1995) Epilepsy Res , vol.21 , pp. 227-230
    • Wong, I.1
  • 73
    • 0032716575 scopus 로고    scopus 로고
    • Psychiatric events during vigabatrin therapy
    • Levinson DF, Devinsky O. Psychiatric events during vigabatrin therapy. Neurology 1999; 53: 1503-11
    • (1999) Neurology , vol.53 , pp. 1503-1511
    • Levinson, D.F.1    Devinsky, O.2
  • 74
    • 0033049950 scopus 로고    scopus 로고
    • Vigabatrin use in psychotic epileptic patients: Report of a prospective pilot study
    • Veggiotti P, de Agostini G, Muzio C, et al. Vigabatrin use in psychotic epileptic patients: report of a prospective pilot study. Acta Neurol Scand 1999; 99: 132-46
    • (1999) Acta Neurol Scand , vol.99 , pp. 132-146
    • Veggiotti, P.1    De Agostini, G.2    Muzio, C.3
  • 75
    • 0034163349 scopus 로고    scopus 로고
    • Long-term open multicentre, add-on trial of vigabatrin in adult resistant partial epilepsy
    • DOI 10.1053/seiz.2000.0382
    • Guberman A, Bruni J. Long-term open multicentre, add-on trial of vigabatrin in adult resistant partial epilepsy. Seizure 2000; 9: 112-8 (Pubitemid 30209799)
    • (2000) Seizure , vol.9 , Issue.2 , pp. 112-118
    • Guberman, A.1    Bruni, J.2
  • 77
    • 0035960602 scopus 로고    scopus 로고
    • Randomized controlled trial of zonisamide for the treatment of refractory partial-onset seizures
    • Faught E, Ayala R, Montouris GG, et al., Zonisamide 922 Trial Group. Randomized controlled trial of zonisamide for the treatment of refractory partial-onset seizures. Neurology 2001; 57: 1774-9 (Pubitemid 33096682)
    • (2001) Neurology , vol.57 , Issue.10 , pp. 1774-1779
    • Faught, E.1    Ayala, R.2    Montouris, G.G.3    Leppik, I.E.4
  • 78
    • 0003142747 scopus 로고
    • Classification
    • Quay HC, Werry JS, editors. 2nd ed. Chichester: John Wiley
    • Quay H. Classification. In: Quay HC, Werry JS, editors. Psychopathological disorders of childhood. 2nd ed. Chichester: John Wiley, 1979; 1-42
    • (1979) Psychopathological Disorders of Childhood , pp. 1-42
    • Quay, H.1
  • 81
    • 0001236176 scopus 로고
    • Methods for reliable longitudinal observation of behaviour
    • Bunney WE, Hamburg DA. Methods for reliable longitudinal observation of behaviour. Arch Gen Psychiatry 1963; 9: 280-94
    • (1963) Arch Gen Psychiatry , vol.9 , pp. 280-294
    • Bunney, W.E.1    Hamburg, D.A.2
  • 82
    • 0002370297 scopus 로고
    • The Brief Psychiatric Rating Scale (BPRS): Recent developments in and scaling
    • Overall JE, Gorham DR. The Brief Psychiatric Rating Scale (BPRS): recent developments in and scaling. Psychopharmacol Bull 1988; 24: 97-9
    • (1988) Psychopharmacol Bull , vol.24 , pp. 97-99
    • Overall, J.E.1    Gorham, D.R.2
  • 84
    • 21344492538 scopus 로고
    • Measurement of severity and treatment response in dysthymia
    • Mason BJ, Kocsis JH, Leon AC. Measurement of severity and treatment response in dysthymia. Ann Gen Psychiatry 1993; 23: 625-31
    • (1993) Ann Gen Psychiatry , vol.23 , pp. 625-631
    • Mason, B.J.1    Kocsis, J.H.2    Leon, A.C.3
  • 85
    • 84965520932 scopus 로고
    • The CES-D Scale: A self-report depression measure for research in the general population
    • Radloff L. The CES-D Scale: a self-report depression measure for research in the general population. Appl Psychol Meas 1977; 1: 385-401
    • (1977) Appl Psychol Meas , vol.1 , pp. 385-401
    • Radloff, L.1
  • 86
    • 0000238671 scopus 로고
    • The Clinical Global Impression (CGI) scale
    • Guy W, editor. Rockville (MD): U.S. Department of Health, Education and Welfare
    • Guy W. The Clinical Global Impression (CGI) scale. In: Guy W, editor. ECDEU assessment manual for psychopharmacology. Rockville (MD): U.S. Department of Health, Education and Welfare, 1976: 218-22
    • (1976) ECDEU Assessment Manual for Psychopharmacology , pp. 218-222
    • Guy, W.1
  • 87
    • 0026333617 scopus 로고
    • A new method for measuring daytime sleepiness: The Epworth Sleepiness Scale
    • Johns MW. A new method for measuring daytime sleepiness: the Epworth Sleepiness Scale. Sleep 1991; 14: 540-5
    • (1991) Sleep , vol.14 , pp. 540-545
    • Johns, M.W.1
  • 89
    • 51549099524 scopus 로고
    • The assessment of anxiety states by rating
    • Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol 1959; 32: 50-5
    • (1959) Br J Med Psychol , vol.32 , pp. 50-55
    • Hamilton, M.1
  • 92
    • 0018425438 scopus 로고
    • A new depression scale designed to be sensitive to change
    • Montgomery SA, Åsberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry 1979; 134: 382-9 (Pubitemid 9136500)
    • (1979) British Journal of Psychiatry , vol.134 , Issue.4 , pp. 382-389
    • Montgomery, S.A.1    Asberg, M.2
  • 93
    • 0000678395 scopus 로고
    • A multiphasic personality schedule (Minnesota): I. Construction of the schedule
    • Hathaway SR, Mckinley JC. A multiphasic personality schedule (Minnesota): I. Construction of the schedule. J Psychol 1940; 10: 249-54
    • (1940) J Psychol , vol.10 , pp. 249-254
    • Hathaway, S.R.1    Mckinley, J.C.2
  • 94
    • 0025984079 scopus 로고
    • Behavioural effects of antiepileptic drugs
    • Smith D, Treiman D, Trimble MR, editors. New York (NY): Raven Press
    • Dodrill CB. Behavioural effects of antiepileptic drugs. In: Smith D, Treiman D, Trimble MR, editors. Neurobehavioural problems in epilepsy. New York (NY): Raven Press, 1991: 213-24
    • (1991) Neurobehavioural Problems in Epilepsy , pp. 213-224
    • Dodrill, C.B.1
  • 95
    • 33646067133 scopus 로고    scopus 로고
    • Rapid detection of major depression in epilepsy: A multicenter study
    • Gilliam FG, Barry JJ, Hermann BP, et al. Rapid detection of major depression in epilepsy: a multicenter study. Lancet Neurol 2006; 5: 399-405
    • (2006) Lancet Neurol , vol.5 , pp. 399-405
    • Gilliam, F.G.1    Barry, J.J.2    Hermann, B.P.3
  • 97
    • 0031930762 scopus 로고    scopus 로고
    • Development and cross-cultural translations of a 31-item quality of life in epilepsy inventory
    • DOI 10.1111/j.1528-1157.1998.tb01278.x
    • Cramer JA, Perrine K, Devinsky O, et al. Development and cross-cultural translation of a 31-item quality of life questionnaire (QOLIE-31). Epilepsia 1998; 39: 81-8 (Pubitemid 28116846)
    • (1998) Epilepsia , vol.39 , Issue.1 , pp. 81-88
    • Cramer, J.A.1    Perrine, K.2    Devinsky, O.3    Bryant-Comstock, L.4    Meador, K.5    Hermann, B.6
  • 99
    • 0000847414 scopus 로고
    • The experience and expression of anger: Construction and validation of an anger expression scale
    • Chesney MA, Rosenman RH, editors. New York (NY): Hemisphere/McGraw-Hill
    • Spielberger CD, Johnson EH, Russell SF, et al. The experience and expression of anger: construction and validation of an anger expression scale. In: Chesney MA, Rosenman RH, editors. Anger and hostility in cardiovascular and behavioral disorders. New York (NY): Hemisphere/McGraw-Hill, 1985: 5-30
    • (1985) Anger and Hostility in Cardiovascular and Behavioral Disorders , pp. 5-30
    • Spielberger, C.D.1    Johnson, E.H.2    Russell, S.F.3
  • 100
    • 0034619028 scopus 로고    scopus 로고
    • Adverse drug reactions: Definitions, diagnosis, and management
    • Edwards IR, Aronson JK. Adverse drug reactions: definitions, diagnosis, and management. Lancet 2000; 356: 1255-9
    • (2000) Lancet , vol.356 , pp. 1255-1259
    • Edwards, I.R.1    Aronson, J.K.2
  • 101
    • 0013524559 scopus 로고    scopus 로고
    • World Health Organisation Collaborating Centre for International Drug Monitoring. Available from [Accessed 2009 Apr 2]
    • World Health Organisation Collaborating Centre for International Drug Monitoring. The WHO adverse reaction terminology: WHO-ART [online]. Available from URL: http://www.umc-products.com/graphics/3149.pdf [Accessed 2009 Apr 2]
    • The WHO Adverse Reaction Terminology: WHO-ART [Online]
  • 103
    • 0015157581 scopus 로고
    • A rating instrument for anxiety disorders
    • Zung WW. A rating instrument for anxiety disorders. Psychosomatics 1971; 12: 371-9
    • (1971) Psychosomatics , vol.12 , pp. 371-379
    • Zung, W.W.1
  • 104
    • 76549189227 scopus 로고
    • A self-rating depression scale
    • Zung WW. A self-rating depression scale. Arch Gen Psychiatry 1965; 12: 63-70
    • (1965) Arch Gen Psychiatry , vol.12 , pp. 63-70
    • Zung, W.W.1
  • 105
    • 0032779116 scopus 로고    scopus 로고
    • Psychiatric syndromes related to antiepileptic drugs
    • Schmitz B. Psychiatric syndromes related to antiepileptic drugs. Epilepsia 1999; 40 Suppl. 10: S65-70
    • (1999) Epilepsia , vol.40 , Issue.SUPPL. 10
    • Schmitz, B.1
  • 106
  • 107
    • 33845717678 scopus 로고    scopus 로고
    • Psychotropic effects of antiepileptic drugs
    • DOI 10.1212/01.wnl.0000247045.85646.c0, PII 0000611420061212000007
    • Ettinger AB. Psychotropic effects of antiepileptic drugs. Neurology 2006; 67: 1916-25 (Pubitemid 44967364)
    • (2006) Neurology , vol.67 , Issue.11 , pp. 1916-1925
    • Ettinger, A.B.1
  • 108
    • 33646059242 scopus 로고    scopus 로고
    • Psychotropic effects of antiepileptic drugs
    • Nadkarni S, Devinsky O. Psychotropic effects of antiepileptic drugs. Epilepsy Curr 2005; 5: 176-81
    • (2005) Epilepsy Curr , vol.5 , pp. 176-181
    • Nadkarni, S.1    Devinsky, O.2
  • 109
    • 84859032810 scopus 로고    scopus 로고
    • Overview: Psychiatric issues
    • Engel J, Pedley TA, editors. 2nd ed. Philadelphia (PA): Lippincott Williams and Wilkins
    • Trimble MR. Overview: psychiatric issues. In: Engel J, Pedley TA, editors. Epilepsy: a comprehensive textbook. 2nd ed. Philadelphia (PA): Lippincott Williams and Wilkins, 2008; 3: 2075-6
    • (2008) Epilepsy: A Comprehensive Textbook , vol.3 , pp. 2075-2076
    • Trimble, M.R.1
  • 110
    • 36949008112 scopus 로고    scopus 로고
    • Are psychiatric adverse events of antiepileptic drugs a unique entity? A study on topiramate and levetiracetam
    • DOI 10.1111/j.1528-1167.2007.01262.x
    • Mula M, Trimble MR, Sander JW. Are psychiatric adverse events of antiepileptic drugs a unique entity? A study on topiramate and levetiracetam. Epilepsia 2007; 48: 2322-6 (Pubitemid 350243412)
    • (2007) Epilepsia , vol.48 , Issue.12 , pp. 2322-2326
    • Mula, M.1    Trimble, M.R.2    Sander, J.W.3
  • 111
    • 62549149951 scopus 로고    scopus 로고
    • Can antiepileptic drugs unmask a susceptibility to psychiatric disorders?
    • Kanner A. Can antiepileptic drugs unmask a susceptibility to psychiatric disorders? Nat Clin Practice Neurol 2009; 5 (3): 132-3
    • (2009) Nat Clin Practice Neurol , vol.5 , Issue.3 , pp. 132-133
    • Kanner, A.1
  • 112
    • 78651268507 scopus 로고    scopus 로고
    • Depression and epilepsy: A bidirectional relation?
    • Kanner AM. Depression and epilepsy: a bidirectional relation? Epilepsia 2011; 52 Suppl. 1: 21-7
    • (2011) Epilepsia , vol.52 , Issue.SUPPL. 1 , pp. 21-27
    • Kanner, A.M.1
  • 113
    • 0033595496 scopus 로고    scopus 로고
    • Positive and negative psychiatric effects of antiepileptic drugs in patients with seizure disorders
    • Ketter TA, Post RM, Theodore WH. Positive and negative psychiatric effects of antiepileptic drugs in seizure disorders. Neurology 1999; 53 (5 Suppl. 2): S53-67 (Pubitemid 29442167)
    • (1999) Neurology , vol.53 , Issue.SUPPL. 2
    • Ketter, T.A.1    Post, R.M.2    Theodore, W.H.3
  • 115
    • 34548046716 scopus 로고    scopus 로고
    • The impact of seizures and adverse effects on global health ratings
    • DOI 10.1016/j.yebeh.2007.05.005, PII S1525505007001801
    • Cramer JA, Brandenburg NA, Xu X, et al. The impact of seizures and adverse effects on global health ratings. Epilepsy Behav 2007; 11: 179-84 (Pubitemid 47279105)
    • (2007) Epilepsy and Behavior , vol.11 , Issue.2 , pp. 179-184
    • Cramer, J.A.1    Brandenburg, N.A.2    Xu, X.3    Vera-Llonch, M.4    Oster, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.