Efficacy and tolerability of levetiracetam during 1-year follow-up in patients with refractory epilepsy

Seizure

Volumn 12, Issue 3, 2003, Pages 131-135

  Ben Menachem, Elinor ^a   Gilland, Eric ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Antiepileptic drugs; Efficacy; Levetiracetam; Prospective trial; Tolerability

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; CLOBAZAM; ETIRACETAM; LAMOTRIGINE; PHENOBARBITAL; PHENYTOIN; PLACEBO; TOPIRAMATE; VALPROIC ACID; VIGABATRIN;

ADOLESCENT; ADULT; AGED; AGGRESSION; ARTICLE; ASTHENIA; BEHAVIOR DISORDER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEMOGRAPHY; DIGESTIVE SYSTEM FUNCTION DISORDER; DISEASE EXACERBATION; DISEASE SEVERITY; DOSE RESPONSE; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG TOLERABILITY; DRUG WITHDRAWAL; EPILEPSY; FATIGUE; FOCAL EPILEPSY; FOLLOW UP; GRAND MAL SEIZURE; HUMAN; IRRITABILITY; MAJOR CLINICAL STUDY; MENTAL DEFICIENCY; MENTAL DISEASE; PARESIS; PRIORITY JOURNAL; PRURITUS; PSYCHOSIS; RASH; SCHOOL CHILD; SOMNOLENCE; STATISTICAL SIGNIFICANCE;

EID: 0037387847     PISSN: 10591311     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1059-1311(02)00251-0     Document Type: Article

References (6)

1. Cramer, J. A., Ben-Menachem, E. and French, J. Review of treatment options for refractory epilepsy: new medications and vagal nerve stimulation. Epilepsy Research 2001; 47: 17-25.
2. Krakow, K., Walker, M., Otoul, C. and Sander, J. W. A. S. Long-term continuation of levetiracetam in patients with refractory epilepsy. Neurology 2001; 56: 1772-1774.
3. Privitera, M. Efficacy of levetiracetam: a review of three pivotal clinical trials. Epilepsia 2001; 42 (Suppl. 4): 31-35.
4. Cereghino, J. J., Biton, V., Abou-Khalil, B., Dreifuss, F., Gauer, L. J. and Leppik, I. Levetiracetam for partial seizures: results of a double-blind, randomized clinical trial. Neurology 2000; 55: 236-242.
5. Ben-Menachem, E. and Falter, U. for the European Levetiracetam Study Group. Efficacy and tolerability of levetiracetam 3000 mg/d in patients with refractory partial seizures: a multicenter, a double-blind, responder-selector study evaluating monotherapy. Epilepsia 2000; 41: 1276-1283.
6. Shorvon, S. D., Lowenthal, A., Janz, D., Bielen and Loiseau, P. for the European Levetiracetam Study Group. Multicenter double-blind, randomized placebo-controlled trial of levetiracetam as add-on therapy in patients with refractory partial seizures. Epilepsia 2000; 41:1179-1186.