Antitumor agents. 289. Design, synthesis, and anti-breast cancer activity in vivo of 4-amino-2 H -benzo[ h ]chromen-2-one and 4-amino-7,8,9,10-tetrahydro- 2 h -benzo[ h ]chromen-2-one analogues with improved water solubility

Journal of Natural Products

Volumn 75, Issue 3, 2012, Pages 370-377

  Dong, Yizhou ^a   Nakagawa Goto, Kyoko ^a   Lai, Chin Yu ^a   Morris Natschke, Susan L ^a   Bastow, Kenneth F ^a   Kim, Yoon ^b   Lee, Eva Y H P ^b   Lee, Kuo Hsiung ^a,c  

^a UNC Hamner Institute for Drug Safety Sciences   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

4 [(4' AMINOPHENYL)AMINO] 2H BENZO[H]CHROMEN 2 ONE; 4 [(4' AMINOPHENYL)AMINO] 7,8,9,10 TETRAHYDRO 2H BENZO[H]CHROMEN 2 ONE; 4 AMINO 2H BENZO[H]CHROMEN 2 ONE; 4 AMINO 7,8,9,10 TETRAHYDRO 2H BENZO[H]CHROMEN 2 ONE; ANTINEOPLASTIC AGENT; CHROMENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; DRUG DESIGN; DRUG EFFECT; DRUG EFFICACY; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; NONHUMAN; STRUCTURE ANALYSIS;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CHROMONES; DRUG DESIGN; HUMANS; MICE; MOLECULAR STRUCTURE; SOLUBILITY; WATER;

MUS;

EID: 84859050353     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np2007878     Document Type: Article

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