The immobilization of gossypol derivative on N-polyvinylpyrrolidone increases its water solubility and modifies membrane-active properties

Journal of Medicinal Chemistry

Volumn 52, Issue 14, 2009, Pages 4119-4125

  Ionov, Maksim ^a,c   Gordiyenko, Nataliya ^b   Olchowik, Ewa ^d   Baram, Nina ^a   Zijaev, Khairulla ^a   Salakhutdinov, Bakhtiyar ^a   Bryszewska, Maria ^c   Zamaraeva, Maria ^a,d  

^a S YU YUNUSOV INSTITUTE OF THE CHEMISTRY OF PLANT SUBSTANCES   (Uzbekistan)

^b NATIONAL EYE INSTITUTE   (United States)

^c UNIVERSITY OF LODZ   (Poland)

^d UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 14; CLIOQUINOL; GOSSYPOL DERIVATIVE; MEGOSIN; POVIDONE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANISOTROPY; ARTICLE; COMPARATIVE STUDY; CONJUGATE; DRUG PENETRATION; DRUG SOLUBILITY; DRUG SYNTHESIS; ELECTRON SPIN RESONANCE; ERYTHROCYTE MEMBRANE; FLUORESCENCE ANALYSIS; HEMOLYSIS; HUMAN; HUMAN CELL; LIVER MITOCHONDRION; MALE; MEMBRANE STRUCTURE; MITOCHONDRIAL PERMEABILITY; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; ERYTHROCYTES; GOSSYPOL; HUMANS; MALE; MITOCHONDRIAL MEMBRANES; POVIDONE; RATS; RATS, WISTAR; SOLUBILITY; STAINING AND LABELING; WATER;

EID: 67650751281     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9002507     Document Type: Article

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