Nrf2 deficiency in myeloid cells is not sufficient to protect mice from high-fat diet-induced adipose tissue inflammation and insulin resistance

Free Radical Biology and Medicine

Volumn 52, Issue 9, 2012, Pages 1708-1715

  Meher, Akshaya K ^a   Sharma, Poonam R ^a   Lira, Vitor A ^a,b   Yamamoto, Masayuki ^c   Kensler, Thomas W ^d   Yan, Zhen ^a,b   Leitinger, Norbert ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Adipocyte macrophage coculture; Bone marrow transplantation; Free radicals; Inflammation; Insulin resistance; Nrf2; Stromal vascular fraction

Indexed keywords

INTERLEUKIN 1BETA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; TRANSCRIPTION FACTOR NRF2;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BONE MARROW CELL; COCULTURE; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; IN VITRO STUDY; INFLAMMATION; INFLAMMATORY CELL; INSULIN RESISTANCE; LIPID DIET; MACROPHAGE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

3T3-L1 CELLS; ADIPOSE TISSUE; ANIMALS; DIETARY FATS; GENE EXPRESSION; GLUCOSE TOLERANCE TEST; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INSULIN RESISTANCE; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; REAL-TIME POLYMERASE CHAIN REACTION;

MUS;

EID: 84858995172     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.02.022     Document Type: Article

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