Size-mediated cytotoxicity of nanocrystalline titanium dioxide, pure and zinc-doped hydroxyapatite nanoparticles in human hepatoma cells

Journal of Nanoparticle Research

Volumn 14, Issue 4, 2012, Pages

  Venkatasubbu, G Devanand ^a   Ramasamy, S ^a   Avadhani, G S ^b   Palanikumar, L ^a   Kumar, J ^a  

^a ANNA UNIVERSITY   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

DNA fragmentation; Environmental and health effects; Human Hepatoma cells; Hydroxyapatite; Titanium dioxide; Toxicity; Zinc doped hydroxyapatite

Indexed keywords

CELL DEATH; DNA; HYDROXYAPATITE; MEDICAL NANOTECHNOLOGY; NANOCRYSTALS; NANOPARTICLES; OXIDE MINERALS; PARTICLE SIZE ANALYSIS; PRECIPITATION (CHEMICAL); TITANIUM DIOXIDE; TOXICITY; TRANSMISSION ELECTRON MICROSCOPY; TUMORS; ZINC COMPOUNDS;

BIOLOGICAL APPLICATIONS; DNA FRAGMENTATION; ENVIRONMENTAL AND HEALTH EFFECTS; HEPATOCELLULAR CARCINOMA CELL; HUMAN HEPATOMA CELLS; NANOCRYSTALLINE TITANIUM DIOXIDE; TITANIUM DIOXIDES (TIO2); ZINC-DOPED HYDROXYAPATITES;

TIO2 NANOPARTICLES;

ANTINEOPLASTIC AGENT; CYCLIN A; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; DNA; HYDROXYAPATITE; NANOPARTICLE; PROTEIN BCL 2; PROTEIN P21; PROTEIN TYROSINE PHOSPHATASE; TITANIUM DIOXIDE; TITANIUM DIOXIDE NANOPARTICLE; UNCLASSIFIED DRUG; ZINC; ZINC DOPED HYDROXYAPATITE NANOPARTICLE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL STRAIN HEPG2; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG SCREENING; HUMAN; HUMAN CELL; IC 50; LIVER CELL CARCINOMA; PARTICLE SIZE; PRIORITY JOURNAL; TEMPERATURE; UPREGULATION;

EID: 84858970389     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-012-0819-3     Document Type: Article

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