Distinct roles of secreted HtrA proteases from gram-negative pathogens in cleaving the junctional protein and tumor suppressor E-cadherin

Journal of Biological Chemistry

Volumn 287, Issue 13, 2012, Pages 10115-10120

  Hoy, Benjamin ^a   Geppert, Tim ^b   Boehm, Manja ^c   Reisen, Felix ^b   Plattner, Patrick ^d   Gadermaier, Gabriele ^a   Sewald, Norbert ^d   Ferreira, Fatima ^a   Briza, Peter ^a   Schneider, Gisbert ^b   Backert, Steffen ^c   Wessler, Silja ^a  

^a UNIVERSITY OF SALZBURG   (Austria)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d BIELEFELD UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE CENTER; BACTERIAL INFECTIONS; BACTERIAL STRESS RESPONSE; CAMPYLOBACTER JEJUNI; CELL ADHERENCE; COMPUTATIONAL MODELING; E-CADHERINS; ENTEROPATHOGENIC ESCHERICHIA COLI; EPITHELIAL BARRIER; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE PATHOGENS; HELICOBACTER PYLORI; HOST CELLS; HTRA PROTEASE; NEISSERIA GONORRHOEAE; PATHOGENIC MECHANISMS; PERIPLASMIC CHAPERONE; PROTEIN QUALITY CONTROL; PROTEOLYTIC ACTIVITIES; SERINE PROTEASE; SHIGELLA FLEXNERI; THERAPEUTIC INTERVENTION; TUMOR SUPPRESSORS;

AMINO ACIDS; BACTERIA; CELL ADHESION; ENZYME ACTIVITY; ESCHERICHIA COLI;

GLYCOPROTEINS;

ALANINE; GLUTAMINE; SERINE PROTEINASE OMI; UVOMORULIN;

AMINO ACID SUBSTITUTION; ARTICLE; CAMPYLOBACTER JEJUNI; CELL ADHESION; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME RELEASE; ENZYME SUBSTRATE; ESCHERICHIA COLI; GENE DELETION; NEISSERIA GONORRHOEAE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHIGELLA FLEXNERI;

BACTERIAL PROTEINS; CACO-2 CELLS; CADHERINS; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; PROTEOLYSIS; SERINE ENDOPEPTIDASES; TUMOR SUPPRESSOR PROTEINS;

BACTERIA (MICROORGANISMS); CAMPYLOBACTER JEJUNI; ESCHERICHIA COLI; HELICOBACTER PYLORI; NEGIBACTERIA; NEISSERIA GONORRHOEAE; SHIGELLA FLEXNERI;

EID: 84858959572     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C111.333419     Document Type: Article

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