Detection of prostaglandin E2-induced dendritic cell migration into the lymph nodes of mice using a 1.5 T clinical MR scanner

NMR in Biomedicine

Volumn 25, Issue 4, 2012, Pages 570-579

  Joo, Hyun Jung ^a,b   Kim, Hoe Suk ^a   Choi, Yoon Seok ^a,b   Kim, Hyeonjin ^a,b   Kim, Seung Ja ^a   Moon, Woo Kyung ^a,b  

^a Seoul National University Hospital   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Dendritic cell; Lymph node; MRI; Prostaglandin E2; Superparamagnetic iron oxide

Indexed keywords

CHEMOKINES; CLINICAL TRIAL; CURRENT TREATMENTS; DENDRITIC CELLS; HIGH RATE; HISTOLOGICAL ANALYSIS; IMAGING METHOD; IN-VIVO; LYMPH NODE; MR SCANNERS; MR SIGNALS; MRI CONTRAST AGENTS; PROSTAGLANDIN E2; PRUSSIAN BLUE; REDUCING COSTS; SUPERPARAMAGNETIC IRON OXIDES; TUMOR NECROSIS FACTORS;

BODY FLUIDS; CELLS; GLYCOPROTEINS; IRON OXIDES; MAGNETIC RESONANCE IMAGING; MAMMALS; SUPERPARAMAGNETISM;

SCANNING;

CHEMOKINE RECEPTOR CCR7; GAMMA INTERFERON; PROSTAGLANDIN E2; SUPERPARAMAGNETIC IRON OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL LABELING; CELL MIGRATION; CELL STRAIN; CELL VIABILITY; DENDRITIC CELL; ENDOCYTOSIS; HISTOLOGY; LYMPH NODE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; CELL LINE; CELL MOVEMENT; CELL TRACKING; DENDRITIC CELLS; DINOPROSTONE; LYMPH NODES; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, INBRED C57BL;

MUS;

EID: 84858861996     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.1774     Document Type: Article

References (32)

1. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392: 245-252.
2. Itano AA, Jenkins MK. Antigen presentation to naive CD4 T cells in the lymph node. Nat. Immunol. 2003; 4: 733-739.
3. Randolph GJ, Angeli V, Swartz MA. Dendritic-cell trafficking to lymph nodes through lymphatic vessels. Nat. Rev. Immunol. 2005; 5: 617-628.
4. Ribas A, Butterfield LH, Glaspy JA, Economou JS. Current developments in cancer vaccines and cellular immunotherapy. J. Clin. Oncol. 2003; 21: 2415-2432.
5. Timmerman JM, Levy R. Dendritic cell vaccines for cancer immunotherapy. Annu. Rev. Med. 1999; 50: 507-529.
6. Figdor CG, de Vries IJ, Lesterhuis WJ, Melief CJ. Dendritic cell immunotherapy: mapping the way. Nat. Med. 2004; 10: 475-480.
7. Walker DG, Laherty R, Tomlinson FH, Chuah T, Schmidt C. Results of a phase I dendritic cell vaccine trial for malignant astrocytoma: potential interaction with adjuvant chemotherapy. J. Clin. Neurosci. 2008; 15: 114-121.
8. Steinman RM, Banchereau J. Taking dendritic cells into medicine. Nature 2007; 449: 419-426.
9. Cavanagh LL, Bonasio R, Mazo IB, Halin C, Cheng G, van der Velden AW, Cariappa A, Chase C, Russell P, Starnbach MN, Koni PA, Pillai S, Weninger W, von Andrian UH. Activation of bone marrow-resident memory T cells by circulating, antigen-bearing dendritic cells. Nat. Immunol. 2005; 6: 1029-1037.
10. Lucignani G, Rescigno M. The role of molecular imaging in the development of dendritic cell-based cancer vaccines. Eur. J. Nucl. Med. Mol. Imaging, 2005; 32: 725-730.
11. Ottobrini L, Martelli C, Trabattoni DL, Clerici M, Lucignani G. Invivo imaging of immune cell trafficking in cancer. Eur. J. Nucl. Med. Mol. Imaging, 2011; 38(5): 949-968.
12. Ahrens ET, Feili-Hariri M, Xu H, Genove G, Morel PA. Receptor-mediated endocytosis of iron-oxide particles provides efficient labeling of dendritic cells for invivo MR imaging. Magn. Reson. Med. 2003; 49: 1006-1013.
13. Arbab AS, Yocum GT, Rad AM, Khakoo AY, Fellowes V, Read EJ, Frank JA. Labeling of cells with ferumoxides-protamine sulfate complexes does not inhibit function or differentiation capacity of hematopoietic or mesenchymal stem cells. NMR Biomed. 2005; 18: 553-559.
14. de Vries IJ, Lesterhuis WJ, Barentsz JO, Verdijk P, van Krieken JH, Boerman OC, Oyen WJ, Bonenkamp JJ, Boezeman JB, Adema GJ, Bulte JW, Scheenen TW, Punt CJ, Heerschap A, Figdor CG. Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat. Biotechnol. 2005; 23: 1407-1413.
15. Long CM, van Laarhoven HW, Bulte JW, Levitsky HI. Magnetovaccination as a novel method to assess and quantify dendritic cell tumor antigen capture and delivery to lymph nodes. Cancer Res. 2009; 69: 3180-3187.
16. Dekaban GA, Snir J, Shrum B, de Chickera S, Willert C, Merrill M, Said EA, Sekaly RP, Foster PJ, O'Connell PJ. Semiquantitation of mouse dendritic cell migration invivo using cellular MRI. J. Immunother. 2009; 32: 240-251.
17. Dieu MC, Vanbervliet B, Vicari A, Bridon JM, Oldham E, Ait-Yahia S, Briere F, Zlotnik A, Lebecque S, Caux C. Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J. Exp. Med. 1998; 188: 373-386.
18. Ohl L, Mohaupt M, Czeloth N, Hintzen G, Kiafard Z, Zwirner J, Blankenstein T, Henning G, Forster R. CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions. Immunity, 2004; 21: 279-288.
19. Luft T, Jefford M, Luetjens P, Toy T, Hochrein H, Masterman KA, Maliszewski C, Shortman K, Cebon J, Maraskovsky E. Functionally distinct dendritic cell (DC) populations induced by physiologic stimuli: prostaglandin E(2) regulates the migratory capacity of specific DC subsets. Blood 2002; 100: 1362-1372.
20. Scandella E, Men Y, Gillessen S, Forster R, Groettrup M. Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells. Blood 2002; 100: 1354-1361.
21. Yen JH, Khayrullina T, Ganea D. PGE2-induced metalloproteinase-9 is essential for dendritic cell migration. Blood, 2008; 111: 260-270.
22. Legler DF, Krause P, Scandella E, Singer E, Groettrup M. Prostaglandin E2 is generally required for human dendritic cell migration and exerts its effect via EP2 and EP4 receptors. J. Immunol. 2006; 176: 966-973.
23. Rubio MT, Means TK, Chakraverty R, Shaffer J, Fudaba Y, Chittenden M, Luster AD, Sykes M. Maturation of human monocyte-derived dendritic cells (MoDCs) in the presence of prostaglandin E2 optimizes CD4 and CD8 T cell-mediated responses to protein antigens: role of PGE2 in chemokine and cytokine expression by MoDCs. Int. Immunol. 2005; 17: 1561-1572.
24. Krause P, Singer E, Darley PI, Klebensberger J, Groettrup M, Legler DF. Prostaglandin E2 is a key factor for monocyte-derived dendritic cell maturation: enhanced T cell stimulatory capacity despite IDO. J. Leukoc. Biol. 2007; 82: 1106-1114.
25. Kabashima K, Sakata D, Nagamachi M, Miyachi Y, Inaba K, Narumiya S. Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells. Nat. Med. 2003; 9: 744-749.
26. Shen Z, Reznikoff G, Dranoff G, Rock KL. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. J. Immunol. 1997; 158: 2723-2730.
27. Kim HS, Oh SY, Joo HJ, Son KR, Song IC, Moon WK. The effects of clinically used MRI contrast agents on the biological properties of human mesenchymal stem cells. NMR Biomed. 2010; 23: 514-522.
28. Wu YL, Ye Q, Foley LM, Hitchens TK, Sato K, Williams JB, Ho C. Insitu labeling of immune cells with iron oxide particles: an approach to detect organ rejection by cellular MRI. Proc. Natl. Acad. Sci. USA, 2006; 103: 1852-1857.
29. Kim HS, Choi Y, Song IC, Moon WK. Magnetic resonance imaging and biological properties of pancreatic islets labeled with iron oxide nanoparticles. NMR Biomed. 2009; 22: 852-856.
30. Verdijk P, Scheenen TW, Lesterhuis WJ, Gambarota G, Veltien AA, Walczak P, Scharenborg NM, Bulte JW, Punt CJ, Heerschap A, Figdor CG, de Vries IJ. Sensitivity of magnetic resonance imaging of dendritic cells for invivo tracking of cellular cancer vaccines. Int. J. Cancer, 2007; 120: 978-984.
31. Reichardt W, Durr C, von Elverfeldt D, Juttner E, Gerlach UV, Yamada M, Smith B, Negrin RS, Zeiser R. Impact of mammalian target of rapamycin inhibition on lymphoid homing and tolerogenic function of nanoparticle-labeled dendritic cells following allogeneic hematopoietic cell transplantation. J. Immunol. 2008; 181: 4770-4779.
32. Briley-Saebo KC, Leboeuf M, Dickson S, Mani V, Fayad ZA, Palucka AK, Banchereau J, Merad M. Longitudinal tracking of human dendritic cells in murine models using magnetic resonance imaging. Magn. Reson. Med. 2010; 64: 1510-1519.