sPLA2-V inhibits EPCR anticoagulant and antiapoptotic properties by accommodating lysophosphatidylcholine or PAF in the hydrophobic groove

Blood

Volumn 119, Issue 12, 2012, Pages 2914-2921

  López Sagaseta, Jacinto ^a   Puy, Cristina ^a   Tamayo, Ibai ^a   Allende, Mikel ^a   Cerveró, Jorge ^a   Velasco, Susana E ^a   Esmon, Charles T ^b   Montes, Ramón ^a   Hermida, José ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL PROTEIN C RECEPTOR; LYSOPHOSPHATIDYLCHOLINE; PHOSPHATIDYLCHOLINE; SECRETORY GROUP 5 PHOSPHOLIPASE A2; SECRETORY PHOSPHOLIPASE A2; THROMBOCYTE ACTIVATING FACTOR; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; LEUKOCYTE ANTIGEN; PHOSPHOLIPASE A2 GROUP V; PROCR PROTEIN, HUMAN; PROTEIN C;

ANIMAL TISSUE; ANTICOAGULATION; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CHEMISTRY; ENZYME ACTIVATION; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; MASS SPECTROMETRY; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SPECTROFLUOROMETRY; THIN LAYER CHROMATOGRAPHY;

ANIMALS; ANTIGENS, CD; CHROMATOGRAPHY, THIN LAYER; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FLOW CYTOMETRY; GROUP V PHOSPHOLIPASES A2; HUMANS; IMMUNOHISTOCHEMISTRY; LYSOPHOSPHATIDYLCHOLINES; MASS SPECTROMETRY; MICE; PLATELET ACTIVATING FACTOR; PROTEIN C; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; SPECTROMETRY, FLUORESCENCE;

EID: 84858852559     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-05-353409     Document Type: Article

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