Development and validation of a gas chromatography-mass spectrometric method for the determination of sildenafil and desmethylsildenafil in whole blood

Journal of Separation Science

Volumn 34, Issue 21, 2011, Pages 3037-3042

  Papoutsis, Ioannis ^a   Nikolaou, Panagiota ^a   Athanaselis, Sotirios ^a   Alevizopoulos, Giorgos ^b   Pistos, Constantinos ^a   Paraskevopoulou, Christina ^a   Spiliopoulou, Chara ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

Author keywords

Blood; Desmethyl sildenafil; Gas chromatography; Mass spectrometry; Sildenafil

Indexed keywords

GAS CHROMATOGRAPHY; MASS SPECTROMETRY; PATIENT MONITORING; PATIENT TREATMENT;

DESMETHYL-SILDENAFIL; ERECTILE DYSFUNCTION; PHARMACOKINETIC STUDIES; PULMONARY HYPERTENSION; SILDENAFIL; SOLID-PHASE EXTRACTION; SPECTROMETRIC METHODS; THERAPEUTIC DRUG MONITORING;

BLOOD;

PIPERAZINE DERIVATIVE; PURINE DERIVATIVE; SILDENAFIL; SULFONE;

ARTICLE; BLOOD; HUMAN; MASS FRAGMENTOGRAPHY; METABOLISM; SENSITIVITY AND SPECIFICITY; VALIDATION STUDY;

GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; PIPERAZINES; PURINES; SENSITIVITY AND SPECIFICITY; SULFONES;

EID: 84858824802     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201100496     Document Type: Article

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