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Volumn 32, Issue 3, 2012, Pages 989-996

Modulation of systemic and intestinal immune response by interleukin-2 therapy in gastrointestinal surgical oncology. Personal experience in the context of current knowledge and future perspectives

Author keywords

Colorectal cancer; Immunology; Interleukin 2; Intestine; Review; Surgery

Indexed keywords

CD11 ANTIGEN; CD123 ANTIGEN; GAMMA INTERFERON; IMIQUIMOD; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 6; VASCULOTROPIN;

EID: 84858764449     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (8)

References (54)
  • 2
    • 0036852241 scopus 로고    scopus 로고
    • Cancer immunoediting: From immunosurveillance to tumor escape
    • DOI 10.1038/ni1102-991
    • Dunn GP, Bruce AT, Ikeda H, Old LJ and Schreiber RD: Cancer immunoediting: from immunosurveillance to tumor escape. Nature Immunol 3(11): 991-998, 2002. (Pubitemid 35363648)
    • (2002) Nature Immunology , vol.3 , Issue.11 , pp. 991-998
    • Dunn, G.P.1    Bruce, A.T.2    Ikeda, H.3    Old, L.J.4    Schreiber, R.D.5
  • 3
    • 0036852191 scopus 로고    scopus 로고
    • Natural selection of tumor variants in the generation of tumor escape phenotypes
    • DOI 10.1038/ni1102-999
    • Khong HT and Restifo NP: Natural selection of tumor variants in the generation of tumor escape phenotypes. Nat Immunol 3(11): 999-1005, 2002. (Pubitemid 35363649)
    • (2002) Nature Immunology , vol.3 , Issue.11 , pp. 999-1005
    • Khong, H.T.1    Restifo, N.P.2
  • 4
    • 34248172324 scopus 로고    scopus 로고
    • Altered macrophage differentiation and immune dysfunction in tumor development
    • DOI 10.1172/JCI31422
    • Sica A and Bronte V: Altered macrophage differentiation and immune dysfunction in tumor development. J Clin Invest 117(5): 1155-1166, 2007. (Pubitemid 46718400)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1155-1166
    • Sica, A.1    Bronte, V.2
  • 5
    • 33748987908 scopus 로고    scopus 로고
    • Cancer despite immunosurveillance: Immunoselection and immunosubversion
    • DOI 10.1038/nri1936, PII NRI1936
    • Zitvogel L, Tesniere A and Kroemer G: Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat Rev Immunol 6(10): 715-727, 2006. (Pubitemid 44453458)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.10 , pp. 715-727
    • Zitvogel, L.1    Tesniere, A.2    Kroemer, G.3
  • 7
    • 9344236512 scopus 로고    scopus 로고
    • Correlation between postoperative infections and long-term survival after colorectal resection for cancer
    • Nespoli A, Gianotti L, Totis M, Bovo G, Nespoli L, Chiodini P and Brivio F: Correlation between postoperative infections and long-term survival after colorectal resection for cancer. Tumori 90(5): 485-90, 2004. (Pubitemid 39556798)
    • (2004) Tumori , vol.90 , Issue.5 , pp. 485-490
    • Nespoli, A.1    Gianotti, L.2    Totis, M.3    Bovo, G.4    Nespoli, L.5    Chiodini, P.6    Brivio, F.7
  • 8
    • 34250183826 scopus 로고    scopus 로고
    • Anastomotic leakage is associated with poor long-term outcome in patients after curative colorectal resection for malignancy
    • Law WL, Choi HK, Lee YM, Ho JW and Seto CL: Anastomotic leakage is associated with poor long-term outcome in patients after curative colorectal resection for malignancy. J Gastrointest Surg 11(1): 8-15, 2007.
    • (2007) J Gastrointest Surg , vol.11 , Issue.1 , pp. 8-15
    • Law, W.L.1    Choi, H.K.2    Lee, Y.M.3    Ho, J.W.4    Seto, C.L.5
  • 9
    • 33751209199 scopus 로고    scopus 로고
    • Cell response to surgery
    • Ni Choileain N and Redmond HP: Cell response to surgery. Arch Surg 141(11): 1132-40, 2006.
    • (2006) Arch Surg , vol.141 , Issue.11 , pp. 1132-1140
    • Ni Choileain, N.1    Redmond, H.P.2
  • 10
    • 11144344922 scopus 로고    scopus 로고
    • Surgical trauma: Hyperinflammation versus immunosuppression?
    • DOI 10.1007/s00423-004-0472-0
    • Menger MD and Vollmar B: Surgical trauma: hyperinflammation versus immunosuppression? Langenbecks Arch Surg 389(6): 475-484, 2004. (Pubitemid 40022444)
    • (2004) Langenbeck's Archives of Surgery , vol.389 , Issue.6 , pp. 475-484
    • Menger, M.D.1    Vollmar, B.2
  • 12
    • 0032987228 scopus 로고    scopus 로고
    • Downregulation of T helper type 1 immune response and altered pro- inflammatory and anti-inflammatory T cell cytokine balance following conventional but not laparoscopic surgery
    • DOI 10.1016/S0002-9610(98)00299-2, PII S0002961098002992
    • Brune IB, Wilke W, Hensler T, Holzmann B and Siewert JR: Downregulation of T helper 1 immune response and altered pro-inflammatory and anti-inflammatory T-cell cytokine balance following conventional but not laparoscopic surgery. Am J Surg 177(1): 55-60, 1999. (Pubitemid 29088998)
    • (1999) American Journal of Surgery , vol.177 , Issue.1 , pp. 55-60
    • Brune, I.B.1    Wilke, W.2    Hensler, T.3    Holzmann, B.4    Siewert, J.-R.5
  • 13
    • 0036833427 scopus 로고    scopus 로고
    • Early postoperative compensatory anti-inflammatory response syndrome is associated with septic complications after major surgical trauma in patients with cancer
    • Mokart D, Capo C, Blache JL, Delpero JR, Houvenaeghel G, Martin C and Mege JL: Early postoperative compensatory anti-inflammatory response syndrome is associated with septic complications after major surgical trauma in patients with cancer. Br J Surg 89(11): 1450-1456, 2002.
    • (2002) Br J Surg , vol.89 , Issue.11 , pp. 1450-1456
    • Mokart, D.1    Capo, C.2    Blache, J.L.3    Delpero, J.R.4    Houvenaeghel, G.5    Martin, C.6    Mege, J.L.7
  • 14
    • 0029925375 scopus 로고    scopus 로고
    • Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma
    • DOI 10.1002/(SICI)1097-0142(19960401)77:7<1303::AID-CNCR12>3.0. CO;2-5
    • Clemente CG, Mihm MC Jr., Bufalino R, Zurrida S, Collini P and Cascinelli N: Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma. Cancer 77(7): 1303-1310, 1996. (Pubitemid 26102328)
    • (1996) Cancer , vol.77 , Issue.7 , pp. 1303-1310
    • Clemente, C.G.1    Mihm Jr., M.C.2    Bufalino, R.3    Zurrida, S.4    Collini, P.5    Cascinelli, N.6
  • 15
    • 24644488201 scopus 로고    scopus 로고
    • The predictive value of CD8, CD4, CD68 and human leukocyte antigen-D-related cells in the prognosis of cutaneous malignant melanoma with vertical growth phase
    • DOI 10.1002/cncr.21283
    • Piras F, Colombari R, Minerba L, Murtas D, Floris C, Maxia C, Corbu A, Perra MT and Sirigu P: The predictive value of CD8, CD4, CD68, and human leukocyte antigen-D-related cells in the prognosis of cutaneous malignant melanoma with vertical growth phase. Cancer 104(6): 1246-1254, 2005. (Pubitemid 41278960)
    • (2005) Cancer , vol.104 , Issue.6 , pp. 1246-1254
    • Piras, F.1    Colombari, R.2    Minerba, L.3    Murtas, D.4    Floris, C.5    Maxia, C.6    Corby, A.7    Perra, M.T.8    Sirigu, P.9
  • 24
    • 0023907493 scopus 로고
    • Interleukin-2: Inception, impact, and implications
    • Smith KA: Interleukin-2: inception, impact, and implications. Science 240(4856): 1169-1176, 1988.
    • (1988) Science , vol.240 , Issue.4856 , pp. 1169-1176
    • Smith, K.A.1
  • 26
    • 55149089270 scopus 로고    scopus 로고
    • Interleukin-2 in the development and control of inflammatory disease
    • Hoyer KK, Dooms H, Barron L and Abbas AK: Interleukin-2 in the development and control of inflammatory disease. Immunol Rev 226: 19-28, 2008.
    • (2008) Immunol Rev , vol.226 , pp. 19-28
    • Hoyer, K.K.1    Dooms, H.2    Barron, L.3    Abbas, A.K.4
  • 27
    • 0020636607 scopus 로고
    • Growth inhibition of an MC-induced mouse sarcoma by TCGF (IL 2)-containing preparations: Preliminary report
    • Bubenik J, Perlmann P, Indrova M, Simova J, Jandlova T and Neuwirt J: Growth inhibition of an MC-induced mouse sarcoma by TCGF (IL 2)-containing preparations. Preliminary report. Cancer Immunol Immunother 14(3): 205-206, 1983. (Pubitemid 13117137)
    • (1983) Cancer Immunology, Immunotherapy , vol.14 , Issue.3 , pp. 205-206
    • Bubenik, J.1    Perlmann, P.2    Indrova, M.3
  • 28
    • 0027125522 scopus 로고
    • FDA panel backs interleukin-2
    • Culliton BJ: FDA panel backs interleukin-2. Nature 355(6358): 287, 1992.
    • (1992) Nature , vol.355 , Issue.6358 , pp. 287
    • Culliton, B.J.1
  • 29
    • 67650165335 scopus 로고    scopus 로고
    • Interleukin-2: Evaluation of route of administration and current delivery systems in cancer therapy
    • Shaker MA and Younes HM: Interleukin-2: evaluation of route of administration and current delivery systems in cancer therapy. J Pharm Sci 98(7): 2268-98, 2009.
    • (2009) J Pharm Sci , vol.98 , Issue.7 , pp. 2268-2298
    • Shaker, M.A.1    Younes, H.M.2
  • 30
    • 0035716152 scopus 로고    scopus 로고
    • Abrogation of surgery-induced IL-6 hypersecretion by presurgical immunotherapy with IL-2 and its importance in the prevention of postoperative complications
    • Brivio F, Lissoni P, Perego M, Lissoni A and Fumagalli L: Abrogation of surgery-induced IL-6 hypersecretion by presurgical immunotherapy with IL-2 and its importance in the prevention of post-operative complications. J Biol Regul Homeost Agents 15(4): 370-374, 2001. (Pubitemid 34162926)
    • (2001) Journal of Biological Regulators and Homeostatic Agents , vol.15 , Issue.4 , pp. 370-374
    • Brivio, F.1    Lissoni, P.2    Perego, M.S.3    Lissoni, A.4    Fumagalli, L.5
  • 31
    • 0033769636 scopus 로고    scopus 로고
    • Surgery-induced decline in circulating dendritic cells in operable cancer patients. A possible explanation of post-operative immunosuppression
    • Brivio F, Gilardi R, Bucocev R, Ferrante R, Rescaldani R, Vigorè R and Fumagalli L: Surgery-induced decline in circulating dendritic cells in operable cancer patients. A possible explanation of post-operative immunosuppression. Hepatogastroenterology 47(35): 1337-1339, 2000.
    • (2000) Hepatogastroenterology , vol.47 , Issue.35 , pp. 1337-1339
    • Brivio, F.1    Gilardi, R.2    Bucocev, R.3    Ferrante, R.4    Rescaldani, R.5    Vigorè, R.6    Fumagalli, L.7
  • 33
    • 34047206219 scopus 로고    scopus 로고
    • Low-dose interleukin-2 administered pre-operatively to patients with gastric cancer activates peripheral and peritumoral lymphocytes but does not affect prognosis
    • DOI 10.1245/s10434-006-9239-x
    • Cesana GC, Romano F, Piacentini G, Scotti M, Brenna A, Bovo G, Vaghi M, Aletti G, Caprotti R, Kaufman H and Uggeri F: Low-dose interleukin-2 administered pre-operatively to patients with gastric cancer activates peripheral and peritumoral lymphocytes but does not affect prognosis. Ann Surg Oncol 14(4): 1295-1304, 2007. (Pubitemid 46536815)
    • (2007) Annals of Surgical Oncology , vol.14 , Issue.4 , pp. 1295-1304
    • Cesana, G.C.1    Romano, F.2    Piacentini, G.3    Scotti, M.4    Brenna, A.5    Bovo, G.6    Vaghi, M.7    Aletti, G.8    Caprotti, R.9    Kaufman, H.10    Uggeri, F.11
  • 36
    • 0036016485 scopus 로고    scopus 로고
    • Effects of IL-2 preoperative immunotherapy on surgery-induced changes in angiogenic regulation and its prevention of VEGF increase and IL-12 decline
    • Brivio F, Lissoni P, Rovelli F, Nespoli A, Uggeri F, Fumagalli L and Gardani G: Effects of IL-2 pre-operative immunotherapy on surgery-induced changes in angiogenetic regulation and its prevention of VEGF increase and IL-12 decline. Hepatogastroenterology 49(44): 385-387, 2002. (Pubitemid 34606558)
    • (2002) Hepato-Gastroenterology , vol.49 , Issue.44 , pp. 385-387
    • Brivio, F.1    Lissoni, P.2    Rovelli, F.3    Nespoli, A.4    Uggeri, F.5    Fumagalli, L.6    Gardani, G.7
  • 37
    • 55849105191 scopus 로고    scopus 로고
    • Interleukin-2 immunotherapy action on innate immunity cells in peripheral blood and tumoral tissue of pancreatic adenocarcinoma patients
    • Brivio F, Fumagalli L, Lissoni P, Nardone A, Nespoli L, Fattori L, Denova M, Chiarelli M and Nespoli A: Interleukin-2 immunotherapy action on innate immunity cells in peripheral blood and tumoral tissue of pancreatic adenocarcinoma patients. Langenbecks Arch Surg 394(1): 115-121, 2009.
    • (2009) Langenbecks Arch Surg , vol.394 , Issue.1 , pp. 115-121
    • Brivio, F.1    Fumagalli, L.2    Lissoni, P.3    Nardone, A.4    Nespoli, L.5    Fattori, L.6    Denova, M.7    Chiarelli, M.8    Nespoli, A.9
  • 39
    • 46749117182 scopus 로고    scopus 로고
    • Phenotype and function of dendritic cells and T-lymphocyte polarization in the human colonic mucosa and adenocarcinoma
    • Gianotti L, Sargenti M, Galbiati F, Nespoli L, Brivio F, Rescigno M and Nespoli A: Phenotype and function of dendritic cells and T-lymphocyte polarization in the human colonic mucosa and adenocarcinoma. Eur J Surg Oncol 34(8): 883-889, 2008.
    • (2008) Eur J Surg Oncol , vol.34 , Issue.8 , pp. 883-889
    • Gianotti, L.1    Sargenti, M.2    Galbiati, F.3    Nespoli, L.4    Brivio, F.5    Rescigno, M.6    Nespoli, A.7
  • 41
    • 0026690469 scopus 로고
    • Effects of a preoperative therapy with interleukin-2 on surgery induced lymphocytopenia in cancer patients
    • Brivio F, Lissoni P, Tisi E, Erba L, Barni S, Tancini G, Rescaldani R, Alderi G and Nociti V: Effects of a preoperative therapy with interleukin-2 on surgery induced lymphocytopenia in cancer patients. Oncology 49(3): 215-218, 1992.
    • (1992) Oncology , vol.49 , Issue.3 , pp. 215-218
    • Brivio, F.1    Lissoni, P.2    Tisi, E.3    Erba, L.4    Barni, S.5    Tancini, G.6    Rescaldani, R.7    Alderi, G.8    Nociti, V.9
  • 42
    • 0034494720 scopus 로고    scopus 로고
    • The Th1-Th2 classification of cellular immune responses: Concepts, current thinking and applications in haematological malignancy
    • DOI 10.1054/blre.2000.0136
    • Lappin MB and Campbell JD: The Th1-Th2 classification of cellular immune responses: concepts, current thinking and applications in haematological malignancy. Blood Rev 14(4): 228-239, 2000. (Pubitemid 32096455)
    • (2000) Blood Reviews , vol.14 , Issue.4 , pp. 228-239
    • Lappin, M.B.1    Campbell, J.D.M.2
  • 43
    • 0031455624 scopus 로고    scopus 로고
    • Radical oncologic surgery affects the circulatory levels of interleukin 10
    • DOI 10.1002/(SICI)1096-9098(199712)66:4<244::AID-JSO4>3.0.CO;2-B
    • Gianotti L, Fortis C, Braga M, Gentilini O, Vignali A and Di Carlo V: Radical oncologic surgery affects the circulatory levels of interleukin 10. J Surg Oncol 66(4): 244-247, 1997. (Pubitemid 28013698)
    • (1997) Journal of Surgical Oncology , vol.66 , Issue.4 , pp. 244-247
    • Gianotti, L.1    Fortis, C.2    Braca, M.3    Gentilini, O.4    Vignali, A.5    Di, C.V.6
  • 46
    • 9244250416 scopus 로고    scopus 로고
    • Mucosal dendritic cells in immunity and inflammation
    • DOI 10.1038/ni1104-1091
    • Kelsall BL and Rescigno M: Mucosal dendritic cells in immunity and inflammation. Nat Immunol 5(11): 1091-1095, 2004. (Pubitemid 39549618)
    • (2004) Nature Immunology , vol.5 , Issue.11 , pp. 1091-1095
    • Kelsall, B.L.1    Rescigno, M.2
  • 49
    • 0029147315 scopus 로고
    • Increased soluble interleukin-2 receptor concentration in plasma predicts a decreased cellular response to IL-2
    • Gooding R, Riches P, Dadian G, Moore J and Gore M: Increased soluble interleukin-2 receptor concentration in plasma predicts a decreased cellular response to IL-2. Br J Cancer 72(2): 452-455, 1995.
    • (1995) Br J Cancer , vol.72 , Issue.2 , pp. 452-455
    • Gooding, R.1    Riches, P.2    Dadian, G.3    Moore, J.4    Gore, M.5
  • 50
    • 0033117849 scopus 로고    scopus 로고
    • Interleukin 2 (IL-2) therapy: Potential advantages of locoregional versus systemic administration
    • DOI 10.1053/ctrv.1998.0115
    • Bernsen MR, Tang JW, Everse LA, Koten JW and Otter WD: Interleukin 2 (IL-2) therapy: potential advantages of locoregional versus systemic administration. Cancer Treat Rev 25(2): 73-82, 1999. (Pubitemid 29353667)
    • (1999) Cancer Treatment Reviews , vol.25 , Issue.2 , pp. 73-82
    • Bernsen, M.R.1    Tang, J.-W.2    Everse, L.A.3    Koten, J.W.4    Den, O.W.5
  • 51
    • 21244457998 scopus 로고    scopus 로고
    • Local interleukin 2 therapy is most effective against cancer when injected intratumourally
    • DOI 10.1007/s00262-004-0627-4
    • Jacobs JJ, Sparendam D and Den Otter W: Local interleukin 2 therapy is most effective against cancer when injected intratumourally. Cancer Immunol Immunother 54(7): 647-654, 2005. (Pubitemid 40884160)
    • (2005) Cancer Immunology, Immunotherapy , vol.54 , Issue.7 , pp. 647-654
    • Jacobs, J.J.L.1    Sparendam, D.2    Den, O.W.3
  • 53
    • 33846212288 scopus 로고    scopus 로고
    • Phase I/II study of topical imiquimod and intralesional interleukin-2 in the treatment of accessible metastases in malignant melanoma
    • DOI 10.1111/j.1365-2133.2006.07664.x
    • Green DS, Bodman-Smith MD, Dalgleish AG and Fischer MD: Phase I/II study of topical imiquimod and intralesional interleukin-2 in the treatment of accessible metastases in malignant melanoma. Br J Dermatol 156(2): 337-345, 2007. (Pubitemid 46095963)
    • (2007) British Journal of Dermatology , vol.156 , Issue.2 , pp. 337-345
    • Green, D.S.1    Bodman-Smith, M.D.2    Dalgleish, A.G.3    Fischer, M.D.4
  • 54
    • 49749143414 scopus 로고    scopus 로고
    • Topical imiquimod and intralesional interleukin-2 increase activated lymphocytes and restore the Th1/Th2 balance in patients with metastastic melanoma
    • Green DS, Dalgleish AG, Belonwu N, Fischer MD and Bodman-Smith MD: Topical imiquimod and intralesional interleukin-2 increase activated lymphocytes and restore the Th1/Th2 balance in patients with metastastic melanoma. Br J Dermatol 159(3): 606-614, 2008.
    • (2008) Br J Dermatol , vol.159 , Issue.3 , pp. 606-614
    • Green, D.S.1    Dalgleish, A.G.2    Belonwu, N.3    Fischer, M.D.4    Bodman-Smith, M.D.5


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