-
1
-
-
0031557684
-
Interleukin-15 promotes angiogenesis in vivo
-
Angiolillo AL, Kanegane H, Sgadari C, Reaman GH, Tosato G (1997) Interleukin-15 promotes angiogenesis in vivo. Biochem Biophys Res Commun 223:231
-
(1997)
Biochem Biophys Res Commun
, vol.223
, pp. 231
-
-
Angiolillo, A.L.1
Kanegane, H.2
Sgadari, C.3
Reaman, G.H.4
Tosato, G.5
-
2
-
-
0033616693
-
Evidence for a structural motif in toxins and interleukin-2 that may be responsible for binding to endothelial cells and initiating vascular leak syndrome
-
Baluna R, Rizo J, Gordon BE, Ghetie V, Vitetta ES (1999) Evidence for a structural motif in toxins and interleukin-2 that may be responsible for binding to endothelial cells and initiating vascular leak syndrome. Proc Nat Acad Sci USA 96:3957
-
(1999)
Proc Nat Acad Sci USA
, vol.96
, pp. 3957
-
-
Baluna, R.1
Rizo, J.2
Gordon, B.E.3
Ghetie, V.4
Vitetta, E.S.5
-
3
-
-
0036387498
-
The mechanism of regression of solid SL2 lymphosarcoma after local IL-2 therapy
-
Baselmans AH, Koten JW, Battermann JJ, Van Dijk JE, Den Otter W (2002) The mechanism of regression of solid SL2 lymphosarcoma after local IL-2 therapy. Cancer Immunol Immunother 51:492
-
(2002)
Cancer Immunol Immunother
, vol.51
, pp. 492
-
-
Baselmans, A.H.1
Koten, J.W.2
Battermann, J.J.3
Van Dijk, J.E.4
Den Otter, W.5
-
4
-
-
0033117849
-
Interleukin 2 (IL-2) therapy: Potential advantages of locoregional versus systemic administration
-
Bernsen MR, Tang JW, Everse LA, Koten JW, Den Otter W (1999) Interleukin 2 (IL-2) therapy: potential advantages of locoregional versus systemic administration. Cancer Treat Rev 25:73
-
(1999)
Cancer Treat Rev
, vol.25
, pp. 73
-
-
Bernsen, M.R.1
Tang, J.W.2
Everse, L.A.3
Koten, J.W.4
Den Otter, W.5
-
5
-
-
0034695606
-
Charcoal suspension for tumour labeling modifies macrophage activity in mice
-
Bonhomme-Faivre L, Depraetere P, Savelli MP, Amdidouche D, Bizi E, Seiller M, Orbach-Arbouys S (2000) Charcoal suspension for tumour labeling modifies macrophage activity in mice. Life Sci 66:817
-
(2000)
Life Sci
, vol.66
, pp. 817
-
-
Bonhomme-Faivre, L.1
Depraetere, P.2
Savelli, M.P.3
Amdidouche, D.4
Bizi, E.5
Seiller, M.6
Orbach-Arbouys, S.7
-
6
-
-
0023034337
-
Immunotherapy of murine sarcomas with interleukin 2. I. Local administration of human recombinant IL-2 preparations
-
Praha
-
Bubenik J, Indrova M, Toulcova A (1986) Immunotherapy of murine sarcomas with interleukin 2. I. Local administration of human recombinant IL-2 preparations. Folia Biol (Praha) 32:384
-
(1986)
Folia Biol
, vol.32
, pp. 384
-
-
Bubenik, J.1
Indrova, M.2
Toulcova, A.3
-
7
-
-
0034880545
-
Leukocyte recruitment at sites of tumour: Dissonant orchestration
-
Carlos TM (2001) Leukocyte recruitment at sites of tumour: dissonant orchestration. J Leukoc Biol 70:171
-
(2001)
J Leukoc Biol
, vol.70
, pp. 171
-
-
Carlos, T.M.1
-
8
-
-
0025685631
-
Mechanisms of tumour rejection in the murine DBA/2-SL2 concomitant immunity system
-
Characiejus D, Dullens HFJ, Den Otter W (1990) Mechanisms of tumour rejection in the murine DBA/2-SL2 concomitant immunity system. Cancer Immunol Immunother 32:179
-
(1990)
Cancer Immunol Immunother
, vol.32
, pp. 179
-
-
Characiejus, D.1
Dullens, H.F.J.2
Den Otter, W.3
-
9
-
-
0026315142
-
Tumour regression by IL-2 mediated stagnation of blood flow
-
De Mik HJ, Koten JW, Maas RA, Dullens HF, Den Otter W (1991) Tumour regression by IL-2 mediated stagnation of blood flow. In Vivo 5:679
-
(1991)
In Vivo
, vol.5
, pp. 679
-
-
De Mik, H.J.1
Koten, J.W.2
Maas, R.A.3
Dullens, H.F.4
Den Otter, W.5
-
10
-
-
0031897859
-
Intravesical interleukin-2 in T1 papillary bladder carcinoma: Regression of marker lesion in 8 of 10 patients
-
Den Otter W, Dobrowolski Z, Bugajski A, Papla B, Van Der Meijden APM, Koten JW, Boon TA, Siedlar M, Zembala M (1998) Intravesical interleukin-2 in T1 papillary bladder carcinoma: regression of marker lesion in 8 of 10 patients. J Urol 159:1183
-
(1998)
J Urol
, vol.159
, pp. 1183
-
-
Den Otter, W.1
Dobrowolski, Z.2
Bugajski, A.3
Papla, B.4
Van Der Meijden, A.P.M.5
Koten, J.W.6
Boon, T.A.7
Siedlar, M.8
Zembala, M.9
-
11
-
-
0029127881
-
Therapy of bovine ocular squamous-cell carcinoma with local doses of interleukin-2: 67% complete regressions after 20 months of follow-up
-
Den Otter W, Hill FWG, Klein WR, Koten JW, Steerenberg PA, De Mulder PHM, Rhode C, Stewart R, Faber JA, Ruitenberg EJ, Rutten VPMG (1995) Therapy of bovine ocular squamous-cell carcinoma with local doses of interleukin-2: 67% complete regressions after 20 months of follow-up. Cancer Immunol Immunother 41:10
-
(1995)
Cancer Immunol Immunother
, vol.41
, pp. 10
-
-
Den Otter, W.1
Hill, F.W.G.2
Klein, W.R.3
Koten, J.W.4
Steerenberg, P.A.5
De Mulder, P.H.M.6
Rhode, C.7
Stewart, R.8
Faber, J.A.9
Ruitenberg, E.J.10
Rutten, V.P.M.G.11
-
12
-
-
0027842747
-
Low doses of interleukin-2 can cure large bovine ocular squamous cell carcinoma
-
Den Otter W, Hill FWG, Klein WR, Koten JW, Steerenberg PA, De Mulder PHM, Rutten VPMG, Ruitenberg EJ (1993) Low doses of interleukin-2 can cure large bovine ocular squamous cell carcinoma. Anticancer Res 13:2453
-
(1993)
Anticancer Res
, vol.13
, pp. 2453
-
-
Den Otter, W.1
Hill, F.W.G.2
Klein, W.R.3
Koten, J.W.4
Steerenberg, P.A.5
De Mulder, P.H.M.6
Rutten, V.P.M.G.7
Ruitenberg, E.J.8
-
13
-
-
0025880753
-
Interleukin-2 acutely induces protein leakage from the microcirculation
-
Edwards M, Schuschke D, Abney D, Miller F (1991) Interleukin-2 acutely induces protein leakage from the microcirculation. J Surg Res 50:609
-
(1991)
J Surg Res
, vol.50
, pp. 609
-
-
Edwards, M.1
Schuschke, D.2
Abney, D.3
Miller, F.4
-
14
-
-
0027344034
-
Pathogenesis of toxicity with human-derived interleukin-2 in experimental animals
-
Harada Y, Yahara I (1993) Pathogenesis of toxicity with human-derived interleukin-2 in experimental animals. Int Rev Exp Pathol 34:37
-
(1993)
Int Rev Exp Pathol
, vol.34
, pp. 37
-
-
Harada, Y.1
Yahara, I.2
-
15
-
-
0028302740
-
Antitumor effect of locally injected low doses of recombinant human interleukin-2 in bovine vulval papilloma and carcinoma
-
Hill FWG, Klein WR, Hoyer MJ, Rutten VPMG, Kock N, Koten JW, Steerenberg PA, Ruitenberg EJ, Den Otter W (1994) Antitumor effect of locally injected low doses of recombinant human interleukin-2 in bovine vulval papilloma and carcinoma. Vet Immunol Immunopathol 41:19
-
(1994)
Vet Immunol Immunopathol
, vol.41
, pp. 19
-
-
Hill, F.W.G.1
Klein, W.R.2
Hoyer, M.J.3
Rutten, V.P.M.G.4
Kock, N.5
Koten, J.W.6
Steerenberg, P.A.7
Ruitenberg, E.J.8
Den Otter, W.9
-
16
-
-
0033840128
-
Overview of interleukin-2 inhalation therapy
-
Huland E, Heinzer H, Huland H, Yung R (2000) Overview of interleukin-2 inhalation therapy. Cancer J Sci Am 6(Suppl 1):104
-
(2000)
Cancer J Sci Am
, vol.6
, Issue.1 SUPPL.
, pp. 104
-
-
Huland, E.1
Heinzer, H.2
Huland, H.3
Yung, R.4
-
17
-
-
0026515571
-
Interleukin-2 by inhalation: Local therapy for metastatic renal cell carcinoma
-
Huland E, Huland H, Heinzer H (1992) Interleukin-2 by inhalation: local therapy for metastatic renal cell carcinoma. J Urol 147:344
-
(1992)
J Urol
, vol.147
, pp. 344
-
-
Huland, E.1
Huland, H.2
Heinzer, H.3
-
18
-
-
0242580050
-
+ T cells that mediate destruction of tumour cells and tumour-associated vasculature: A novel mechanism for IL-2
-
+ T cells that mediate destruction of tumour cells and tumour-associated vasculature: a novel mechanism for IL-2. J Immunol 171:5051
-
(2003)
J Immunol
, vol.171
, pp. 5051
-
-
Jackaman, C.1
Bundell, C.S.2
Kinnear, B.F.3
Smith, A.M.4
Fillion, P.5
Van Hagen, D.6
Robinson, B.W.S.7
Nelson, D.J.8
-
19
-
-
0034112412
-
Methyl green-pyronine staining of porcine organotypic skin explant cultures: An alternative model for screening skin irritants
-
Jacobs JJL, Lehé C, Cammans KDA, Das PK, Elliott GR (2000) Methyl green-pyronine staining of porcine organotypic skin explant cultures: an alternative model for screening skin irritants. ATLA 28:279
-
(2000)
ATLA
, vol.28
, pp. 279
-
-
Jacobs, J.J.L.1
Lehé, C.2
Cammans, K.D.A.3
Das, P.K.4
Elliott, G.R.5
-
20
-
-
0008526616
-
Screening of skin irritant by RNA detection as a viability marker in porcine organotypic skin explants
-
Jacobs JJL, Lehé C, Cammans KDA, Das PK, Elliott GR (2000) Screening of skin irritant by RNA detection as a viability marker in porcine organotypic skin explants. In: Progress in the reduction refinement replacement of animal experimentation, vol 31A, pp 601
-
(2000)
Progress in the Reduction Refinement Replacement of Animal Experimentation
, vol.31 A
, pp. 601
-
-
Jacobs, J.J.L.1
Lehé, C.2
Cammans, K.D.A.3
Das, P.K.4
Elliott, G.R.5
-
21
-
-
0036773245
-
An in vitro model for detecting skin irritants: Methyl green-pyronine staining of human skin explant cultures
-
Jacobs JJL, Lehé C, Cammans KDA, Das PK, Elliott GR (2002) An in vitro model for detecting skin irritants: methyl green-pyronine staining of human skin explant cultures. Toxicol Vitro 16:581
-
(2002)
Toxicol Vitro
, vol.16
, pp. 581
-
-
Jacobs, J.J.L.1
Lehé, C.2
Cammans, K.D.A.3
Das, P.K.4
Elliott, G.R.5
-
22
-
-
0142248878
-
IL-2 loaded dextran microspheres with attractive histocompatibility properties for local IL-2 cancer therapy
-
Koten JW, Van Luyn MJA, Cadée JA, Brouwer L, Hennink WE, Bijleveld C, Den Otter W (2003) IL-2 loaded dextran microspheres with attractive histocompatibility properties for local IL-2 cancer therapy. Cytokine 24:57
-
(2003)
Cytokine
, vol.24
, pp. 57
-
-
Koten, J.W.1
Van Luyn, M.J.A.2
Cadée, J.A.3
Brouwer, L.4
Hennink, W.E.5
Bijleveld, C.6
Den Otter, W.7
-
23
-
-
0141650696
-
A case of hepatocellular carcinoma (HCC): Treatment with local application of alcohol and interleukin 2 (IL-2)
-
Krastev Z, Koltchakov V, Popov D, Alexiev A, Koten J-W, Den Otter W (2003) A case of hepatocellular carcinoma (HCC): treatment with local application of alcohol and interleukin 2 (IL-2). Cancer Immunol Immunother 50:1647
-
(2003)
Cancer Immunol Immunother
, vol.50
, pp. 1647
-
-
Krastev, Z.1
Koltchakov, V.2
Popov, D.3
Alexiev, A.4
Koten, J.-W.5
Den Otter, W.6
-
24
-
-
0034918404
-
A mesothelioma that is sensitive to locally applied IL-2
-
Krastev Z, Koltchakov V, Vladov N, Popov D, Milev A, Koten JW, Den Otter W (2001) A mesothelioma that is sensitive to locally applied IL-2. Cancer Immunol Immunother 50:226
-
(2001)
Cancer Immunol Immunother
, vol.50
, pp. 226
-
-
Krastev, Z.1
Koltchakov, V.2
Vladov, N.3
Popov, D.4
Milev, A.5
Koten, J.W.6
Den Otter, W.7
-
25
-
-
0029780462
-
Effect of recombinant human interleukin 2 on neutrophil adherence to endothelial cells in vitro
-
Li J, Gyorffy S, Lee S, Kwok CS (1996) Effect of recombinant human interleukin 2 on neutrophil adherence to endothelial cells in vitro. Inflammation 20:361
-
(1996)
Inflammation
, vol.20
, pp. 361
-
-
Li, J.1
Gyorffy, S.2
Lee, S.3
Kwok, C.S.4
-
26
-
-
0032990632
-
Activation of endothelium by immunotherapy with interleukin-2 in patients with malignant disorders
-
Locker GJ, Kapiotis S, Veitl M, Mader RM, Stoiser B, Kofler J, Sieder AE, Rainer H, Steger GG, Mannhalter C, Wagner OF (1999) Activation of endothelium by immunotherapy with interleukin-2 in patients with malignant disorders. Br J Haematol 105:912
-
(1999)
Br J Haematol
, vol.105
, pp. 912
-
-
Locker, G.J.1
Kapiotis, S.2
Veitl, M.3
Mader, R.M.4
Stoiser, B.5
Kofler, J.6
Sieder, A.E.7
Rainer, H.8
Steger, G.G.9
Mannhalter, C.10
Wagner, O.F.11
-
27
-
-
0027240516
-
Transfer of tumour immunity by both CD4+ and CD8+ tumour infiltrating T lymphocytes activated in vivo by IL-2 therapy of tumour bearing mice
-
Maas RA, Becker MJ, Weimar IS, De Nooy JC, Dullens HFJ, Den Otter W (1993) Transfer of tumour immunity by both CD4+ and CD8+ tumour infiltrating T lymphocytes activated in vivo by IL-2 therapy of tumour bearing mice. Immunobiology 188:281
-
(1993)
Immunobiology
, vol.188
, pp. 281
-
-
Maas, R.A.1
Becker, M.J.2
Weimar, I.S.3
De Nooy, J.C.4
Dullens, H.F.J.5
Den Otter, W.6
-
28
-
-
0024832082
-
Immunotherapy of mice with a large burden of disseminated lymphoma with low-dose interleukin 2
-
Maas RA, Dullens HFJ, De Jong WH, Den Otter W (1989) Immunotherapy of mice with a large burden of disseminated lymphoma with low-dose interleukin 2. Cancer Res 49:7037
-
(1989)
Cancer Res
, vol.49
, pp. 7037
-
-
Maas, R.A.1
Dullens, H.F.J.2
De Jong, W.H.3
Den Otter, W.4
-
29
-
-
0026321308
-
Mechanisms of tumour regression induced by low doses of interleukin-2
-
Maas RA, Dullens HFJ, Den Otter W (1991) Mechanisms of tumour regression induced by low doses of interleukin-2. In Vivo 5:637
-
(1991)
In Vivo
, vol.5
, pp. 637
-
-
Maas, R.A.1
Dullens, H.F.J.2
Den Otter, W.3
-
30
-
-
0027305305
-
Histological analysis of IL-2 induced regression of murine solid SL2-tumors
-
Maas RA, Dullens HFJ, Henk D, Van Weering J, De Mik HJ, Koten JW, Belger RJ, Den Otter W (1993) Histological analysis of IL-2 induced regression of murine solid SL2-tumors. Biotherapy 6:83
-
(1993)
Biotherapy
, vol.6
, pp. 83
-
-
Maas, R.A.1
Dullens, H.F.J.2
Henk, D.3
Van Weering, J.4
De Mik, H.J.5
Koten, J.W.6
Belger, R.J.7
Den Otter, W.8
-
32
-
-
1442336028
-
- cells correlates with the therapeutic efficacy of lymphoma treatment with IL-2 and/or IL-12
-
- cells correlates with the therapeutic efficacy of lymphoma treatment with IL-2 and/or IL-12. J Immunother 27:107
-
(2004)
J Immunother
, vol.27
, pp. 107
-
-
Masztalerz, A.1
Everse, L.A.2
Den Otter, W.3
-
34
-
-
0028170272
-
A methyl green-pyronin technique for demonstrating cell death in the murine tumour S180
-
Moffitt P (1994) A methyl green-pyronin technique for demonstrating cell death in the murine tumour S180. Cell Biol International 18:677
-
(1994)
Cell Biol International
, vol.18
, pp. 677
-
-
Moffitt, P.1
-
35
-
-
0022534622
-
Extravasation of intravascular fluid mediated by the systemic administration of recombinant interleukin 2
-
Rosenstein M, Ettinghausen SE, Rosenberg SA (1986) Extravasation of intravascular fluid mediated by the systemic administration of recombinant interleukin 2. J Immunol 137:1735
-
(1986)
J Immunol
, vol.137
, pp. 1735
-
-
Rosenstein, M.1
Ettinghausen, S.E.2
Rosenberg, S.A.3
-
36
-
-
0024376550
-
Local interleukin-2 therapy in bovine ocular squamous cell carcinoma. A pilot study
-
Rutten VPMG, Klein WR, De Jong WA, Misdorp W, Den Otter W, Steerenberg PA, De Jong WH, Ruitenberg EJ (1989) Local interleukin-2 therapy in bovine ocular squamous cell carcinoma. A pilot study. Cancer Immunol Immunother 30:165
-
(1989)
Cancer Immunol Immunother
, vol.30
, pp. 165
-
-
Rutten, V.P.M.G.1
Klein, W.R.2
De Jong, W.A.3
Misdorp, W.4
Den Otter, W.5
Steerenberg, P.A.6
De Jong, W.H.7
Ruitenberg, E.J.8
-
37
-
-
0037382915
-
Comparison of the efficacy of local treatment of equine sarcoids with IL-2 or cisplatin/IL-2
-
Spoormakers TJP, Klein WR, Jacobs JJL, Van Den Ingh TSGAM, Koten JW, Den Otter W (2003) Comparison of the efficacy of local treatment of equine sarcoids with IL-2 or cisplatin/IL-2. Cancer Immunol Immunother 52:179
-
(2003)
Cancer Immunol Immunother
, vol.52
, pp. 179
-
-
Spoormakers, T.J.P.1
Klein, W.R.2
Jacobs, J.J.L.3
Van Den Ingh, T.S.G.A.M.4
Koten, J.W.5
Den Otter, W.6
-
38
-
-
0000957152
-
Local low-dose IL-2 therapy of tumours in companion animals
-
Ziekman PGPM (1999) Local low-dose IL-2 therapy of tumours in companion animals. Anticancer Res 19:2016
-
(1999)
Anticancer Res
, vol.19
, pp. 2016
-
-
Ziekman, P.G.P.M.1
-
39
-
-
22144471231
-
Treatment of stage III-IV nasopharyngeal carcinomas by external beam irradiation and local low doses of IL-2
-
(in press) (DOI: 10.1007/s00262-004-0641-6)
-
Jacobs JJL, Hordijk GJ, Jürgenliemk-Schulz IM, Terhaard CHJ, Koten JW, Battermann JJ, Den Otter W. Treatment of stage III-IV nasopharyngeal carcinomas by external beam irradiation and local low doses of IL-2. Cancer Immunol Immunother 54(in press) (DOI: 10.1007/s00262-004-0641-6)
-
Cancer Immunol Immunother
, vol.54
-
-
Jacobs, J.J.L.1
Hordijk, G.J.2
Jürgenliemk-Schulz, I.M.3
Terhaard, C.H.J.4
Koten, J.W.5
Battermann, J.J.6
Den Otter, W.7
-
40
-
-
21244456595
-
-
Submitted
-
Krastev Z, Koltchakov V, Tomova R, Deredjian S, Alexiev A, Popov D, Tomov B, Bijleveld C, Koten JW, Jacobs JJL, Den Otter W. Locoregional IL-2 therapy in terminal tumour cases presented in our clinic of gastroenterology: intratumoural IL-2 has beneficial effects in 6 out of 7 patients. (Submitted)
-
Locoregional IL-2 Therapy in Terminal Tumour Cases Presented in Our Clinic of Gastroenterology: Intratumoural IL-2 Has Beneficial Effects in 6 out of 7 Patients
-
-
Krastev, Z.1
Koltchakov, V.2
Tomova, R.3
Deredjian, S.4
Alexiev, A.5
Popov, D.6
Tomov, B.7
Bijleveld, C.8
Koten, J.W.9
Jacobs, J.J.L.10
Den Otter, W.11
|