The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal): Evaluation of impacts on fish liver, by histopathology, stereology, vitellogenin and CYP1A immunohistochemistry, after sub-acute exposures of the zebrafish model

Environmental Toxicology and Pharmacology

Volumn 34, Issue 1, 2012, Pages 34-45

  Madureira, Tânia Vieira ^a,b,c   Rocha, Maria João ^a,b,c   Cruzeiro, Catarina ^c   Rodrigues, Iolanda ^b,c   Monteiro, Rogério A F ^b,c   Rocha, Eduardo ^b,c  

^a UNIVERSITY INSTITUTE OF HEALTH SCIENCES IUCS   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c UNIVERSITY OF PORTO   (Portugal)

Author keywords

Immunohistochemistry; Liver; Mixtures; Pharmaceuticals; Stereology; Zebrafish

Indexed keywords

CARBAMAZEPINE; CYTOCHROME P450 1A; FENOFIBRATE; PROPRANOLOL; SULFAMETHOXAZOLE; TRIMETHOPRIM; VITELLOGENIN;

ANIMAL TISSUE; ARTICLE; CELL VOLUME; CONTROLLED STUDY; DETOXIFICATION; DRUG EXPOSURE; EOSINOPHILIA; ESTUARY; FEMALE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIVER CELL; LIVER TOXICITY; MALE; NONHUMAN; PORTUGAL; PRIORITY JOURNAL; SEX DIFFERENCE; STEREOLOGY; WATER POLLUTION; ZEBRA FISH;

ANIMALS; CARBAMAZEPINE; CYTOCHROME P-450 CYP1A1; FEMALE; FENOFIBRATE; FISH PROTEINS; LIVER; MALE; PORTUGAL; PROPRANOLOL; RIVERS; SULFAMETHOXAZOLE; TRIMETHOPRIM; VITELLOGENINS; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH;

DANIO RERIO;

EID: 84858725544     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2012.02.007     Document Type: Article

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