Acute toxicity of carbamazepine to juvenile rainbow trout (Oncorhynchus mykiss): Effects on antioxidant responses, hematological parameters and hepatic EROD

Ecotoxicology and Environmental Safety

Volumn 74, Issue 3, 2011, Pages 319-327

  Li, Zhi Hua ^a,b,c   Zlabek, Vladimir ^b   Velisek, Josef ^b   Grabic, Roman ^b   Machova, Jana ^b   Kolarova, Jitka ^b   Li, Ping ^b,c   Randak, Tomas ^b  

^a SOUTHWEST UNIVERSITY   (China)

^b UNIVERSITY OF SOUTH BOHEMIA   (Czech Republic)

^c SOUTH CHINA SEA FISHERIES RESEARCH INSTITUTE   (China)

Author keywords

Blood indices; Fish; Hepatic EROD; Oxidative stress biomarkers; Pharmaceutical residues

Indexed keywords

ANTIOXIDANT; CARBAMAZEPINE; CATALASE; ETHOXYRESORUFIN DEETHYLASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GROUND WATER; SUPEROXIDE DISMUTASE; SURFACE WATER; XENOBIOTIC AGENT;

ANALYTICAL METHOD; ANTIOXIDANT; AQUATIC ENVIRONMENT; BIOMARKER; BLOOD; ENZYME ACTIVITY; HEMATOLOGY; JUVENILE; POLLUTION EFFECT; POLLUTION EXPOSURE; SALMONID; TOXICITY; TOXICOLOGY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUATIC ENVIRONMENT; ARTICLE; BIOASSAY; BRAIN TISSUE; CONTROLLED STUDY; DRUG EXPOSURE; ECOTOXICITY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ERYTHROCYTE VOLUME; GILL; HEMATOLOGICAL PARAMETERS; HEMOGLOBIN DETERMINATION; INTESTINE; LC 50; LIPID PEROXIDATION; LIVER PARENCHYMA; LYMPHOCYTE COUNT; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; MONOCYTE; MUSCLE TISSUE; NEUTROPHIL COUNT; NONHUMAN; OXIDATIVE STRESS; RAINBOW TROUT; TOXICITY TESTING;

ACUTE TOXICITY TESTS; ANIMALS; ANTICONVULSANTS; BRAIN; CARBAMAZEPINE; CATALASE; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; GILLS; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; INTESTINES; LIVER; MUSCLES; ONCORHYNCHUS MYKISS; SUPEROXIDE DISMUTASE; WATER POLLUTANTS, CHEMICAL;

ONCORHYNCHUS MYKISS;

EID: 79951945406     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2010.09.008     Document Type: Article

References (69)

1. Andreozzi R., Marotta R., Pinto G., Pollio A. Carbamazepine in water: persistence in the environment, ozonation treatment and preliminary assessment on algal toxicity. Water Res. 2002, 36:2869-2877.
2. Bainy A.C.D., Saito E., Carvalho P.S.M., Junqueira V.B.C. Oxidative stress in gill, erythrocytes, liver and kidney of Nile tilapia (Oreochromis niloticus) from a polluted site. Aquat. Toxicol. 1996, 34:151-162.
3. Ballesteros M.L., Wunderlin D.A., Bistoni M.A. Oxidative stress responses in different organs of Jenynsia multidentata exposed to endosulfan. Ecotoxicol. Environ. Saf. 2009, 72:199-205.
4. Beers R.F., Sizer I.W. A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J. Biol. Chem. 1952, 195:133-140.
5. Bliss C.I. The calculation of the dosage mortality curve. Ann. Appl. Biol. 1935, 22:134-167.
6. Booth C.E., Mcdonald D.G., Simons B.P., Wood C.M. Effects of aluminum and low pH on net ion fluxes and ion balance in the Brook trout (Salvelinus fontinalis). Can. J. Fish. Aquat. Sci. 1988, 45:1563-1574.
7. Brackenbury T.D., Appleton C.C. Acute toxicity evaluation of the plant molluscicide, Apodytes dimidiata (Icacinaceae), to Eisenia fetida (Oligochaeta) and Oreochromis mossambicus (Cichlidae) in South Africa. Acta Trop. 1997, 63:1-14.
8. Bradford M.M. Rapid and sensitive method for quantitation of microgram quantities of protein utilizing principle of protein dye binding. Anal. Biochem. 1976, 72:248-254.
9. Carbis C.R., Rawlin G.T., Grant P., Mitchell G.F., Anderson J.W., McCauley I. A study of feral carp, Cyprinus carpio L, exposed to Microcystis aeruginosa at Lake Mokoan, Australia, and possible implications for fish health. J. Fish Dis 1997, 20:81-91.
10. Carlberg I., Mannervik B. Purification and characterization of flavoenzyme glutathione reductase from rat liver. J. Biol. Chem. 1975, 250:5475-5480.
11. Cazenave J., Bistoni M.D.A., Pesce S.F., Wunderlin D.A. Differential detoxification and antioxidant response in diverse organs of Corydoras paleatus experimentally exposed to microcystin-RR. Aquat. Toxicol. 2006, 76:1-12.
12. Cole M.B., Arnold D.E., Watten B.J., Krise W.F. Haematological and physiological responses of brook charr, to untreated and limestone-neutralized acid mine drainage. J. Fish Biol. 2001, 59:79-91.
13. Crane M., Watts C., Boucard T. Chronic aquatic environmental risks from exposure to human pharmaceuticals. Sci. Total Environ. 2006, 367:23-41.
14. El-Sayed Y.S., Saad T.T., El-Bahr S.M. Acute intoxication of deltamethrin in monosex Nile tilapia, Oreochromis niloticus with special reference to the clinical, biochemical and haematological effects. Environ. Toxicol. Pharmacol. 2007, 24:212-217.
15. Fatima M., Mandiki S.N.M., Douxfils J., Silvestre F., Coppe P., Kestemont P. Combined effects of herbicides on biomarkers reflecting immune-endocrine interactions in goldfish immune and antioxidant effects. Aquat. Toxicol. 2007, 81:159-167.
16. Fent K., Weston A.A., Caminada D. Ecotoxicology of human pharmaceuticals. Aquat. Toxicol. 2006, 76:122-159.
17. Ferrari B., Mons R., Vollat B., Fraysse B., Paxeus N., Lo Giudice R., Pollio A., Garric J. Environmental risk assessment of six human pharmaceuticals: are the current environmental risk assessment procedures sufficient for the protection of the aquatic environment?. Environ. Toxicol. Chem. 2004, 23:1344-1354.
18. Gate L., Paul J., Ba G.N., Tew K.D., Tapiero H. Oxidative stress induced in pathologies: the role of antioxidants. Biomed. Pharmacother. 1999, 53:169-180.
19. Hahn M.E., Stegeman J.J. Regulation of cytochrome P4501A1 in teleosts-sustained induction of Cyp1A1 messenger-RNA, protein, and catalytic activity by 2,3,7,8-tetrachlorodibenzofuran in the marine fish Stenotomus chrysops. Toxicol. Appl. Pharmacol. 1994, 127:187-198.
20. Halling-Sorensen B., Nielsen S.N., Lanzky P.F., Ingerslev F., Lutzhoft H.C.H., Jorgensen S.E. Occurrence, fate and effects of pharmaceutical substances in the environment-A review. Chemosphere 1998, 36:357-394.
21. Hochachka P.W., Buck L.T., Doll C.J., Land S.C. Unifying theory of hypoxia tolerance: molecular metabolic defense and rescue mechanisms for surviving oxygen lack. Proc. Natl. Acad. Sci. USA 1996, 93:9493-9498.
22. Huang C.H., Chang R.J., Huang S.L., Chen W.L. Dietary vitamin E supplementation affects tissue lipid peroxidation of hybrid tilapia, Oreochromis niloticus x O-aureus. Comp. Biochem. Physiol. B 2003, 134:265-270.
23. Ishikawa N.M., Ranzani-Paiva M.J.T., Lombardi J.V., Ferreira C.M. Hematological parameters in Nile Tilapia, Oreochromis niloticus exposed to sub-letal concentrations of mercury. Braz. Arch. Biol. Technol. 2007, 50:619-626.
24. Isik I., Celik I. Acute effects of methyl parathion and diazinon as inducers for oxidative stress on certain biomarkers in various tissues of rainbowtrout (Oncorhynchus mykiss). Pest. Biochem. Physiol. 2008, 92:38-42.
25. Jonsson E.M., Abrahamson A., Brunstrom B., Brandt I. Cytochrome P4501A induction in rainbow trout gills and liver following exposure to waterborne indigo, benzo[a]pyrene and 3,3',4,4',5-pentachlorobiphenyl. Aquat. Toxicol. 2006, 79:226-232.
26. Kennedy S.W., Jones S.P. Simultaneous measurement of Cytochrome P4501a catalytic activity and total protein concentration with a fluorescence plate reader. Anal. Biochem. 1994, 222:217-223.
27. Kim S.D., Cho J., Kim I.S., Vanderford B.J., Snyder S.A. Occurrence and removal of pharmaceuticals and endocrine disruptors in South Korean surface, drinking, and waste waters. Water Res. 2007, 41:1013-1021.
28. Kim Y., Choi K., Jung J.Y., Park S., Kim P.G., Park J. Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem and six major sulfonamides, and their potential ecological risks in Korea. Environ. Int. 2007, 33:370-375.
29. Kirby M.F., Neall P., Bateman T.A., Thain J.E. Hepatic ethoxyresorufin O-deethylase (EROD) activity in flounder (Platichthys flesus) from contaminant impacted estuaries of the United Kingdom: continued monitoring 1999-2001. Mar. Pollut. Bull. 2004, 49:71-78.
30. Lawrence R.A., Burk R.F. Glutathione peroxidase activity in selenium deficient rat liver. Biochem. Biophys. Res. Commun. 1976, 71:952-958.
31. Lennquist A., Celander M.C., Forlin L. Effects of medetomidine on hepatic EROD activity in three species of fish. Ecotoxicol. Environ. Safe. 2008, 69:74-79.
32. Lenz A.G., Costabel U., Shaltiel S., Levine R.L. Determination of carbonyl groups in oxidatively modified proteins by reduction with tritiated sodium borohydride. Anal. Biochem. 1989, 177:419-425.
33. Li Z.H., Li P., Rodina M., Randak T. Effect of human pharmaceutical Carbamazepine on the quality parameters and oxidative stress in common carp (Cyprinus carpio L.) spermatozoa. Chemosphere 2010, 80:530-534.
34. Li Z.H., Randak T. Residual pharmaceutically active compounds (PhACs) in aquatic environment-status, toxicity and kinetics: a review. Vet. Med. 2009, 52:295-314.
35. Li Z.H., Velisek J., Zlabek V., Grabic R., Machova J., Kolarova J., Randak T. Hepatic antioxidant status and hematological parameters in rainbow trout, Oncorhynchus mykiss, after chronic exposure to carbamazepine. Chem. Biol. Interact. 2010, 183:98-104.
36. Li Z.H., Zlabek V., Grabic R., Li P., Machova J., Velisek J., Randak T. Effects of exposure to sublethal propiconazole on the antioxidant defense system and Na+-K+-ATPase activity in brain of rainbow trout, Oncorhynchus mykiss. Aquat. Toxicol. 2010, 98:297-303.
37. +-ATPase activity in gill of rainbow trout, Oncorhynchus mykiss, chronically treated with carbamazepine. Chemosphere 2009, 77:1476-1481.
38. Li Z.H., Zlabek V., Velisek J., Grabic R., Machova J., Randak T. Enzymatic alterations and RNA/DNA ratio in intestine of rainbow trout, Oncorhynchus mykiss, induced by chronic exposure to carbamazepine. Ecotoxicology 2010, 19:872-878.
39. Li Z.H., Zlabek V., Velisek J., Grabic R., Machova J., Randak T. Modulation of antioxidant defence system in brain of rainbow trout (Oncorhynchus mykiss) after chronic carbamazepine treatment. Comp. Biochem. Physiol. C 2010, 151:137-141.
40. Li Z.H., Zlabek V., Velisek J., Grabic R., Machova J., Randak T. Physiological condition status and muscle-based biomarkers in rainbow trout (Oncorhynchus mykiss), after long-term exposure to carbamazepine. J. Appl. Toxicol. 2010, 30:197-203.
41. Lohner T.W., Reash R.J., Willet V.E., Rose L.A. Assessment of tolerant sunfish populations (Lepomis sp.) inhabiting selenium-laden coal ash effluents-1. Hematological and population level assessment. Ecotoxicol. Environ. Saf. 2001, 50:203-216.
42. Lushchak V.I., Bagnyukova T.V., Husak V.V., Luzhna L.I., Lushchak O.V., Storey K.B. Hyperoxia results in transient oxidative stress and an adaptive response by antioxidant enzymes in goldfish tissues. Int. J. Biochem. Cell Biol. 2005, 37:1670-1680.
43. Madhusudhanan N., KavithaLakshmi S.N., Shanmugasundaram K.R., Shanmugasundaram E.R.B. Oxidative damage to lipids and proteins induced by aflatoxin B-1 in fish (Labeo rohita)-protective role of Amrita Bindu. Environ. Toxicol. Pharmacol. 2004, 17:73-77.
44. Marklund S., Marklund G. Involvement of superoxide anion radical in autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 1974, 47:469-474.
45. Mates J.M. Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology. Toxicology 2000, 153:83-104.
46. Miller L.L., Wang F., Palace V.P., Hontela A. Effects of acute and subchronic exposures to waterborne selenite on the physiological stress response and oxidative stress indicators in juvenile rainbow trout. Aquat. Toxicol. 2007, 83:263-271.
47. Mishra R., Shukla S.P. Endosulfan effects on muscle malate dehydrogenase of the freshwater catfish Clarias batrachus. Ecotoxicol. Environ. Saf. 2003, 56:425-433.
48. Murad A., Houston A.H. Leukocytes and leukopoietic capacity in goldfish, Carassius auratus, exposed to sublethal levels of cadmium. Aquat. Toxicol. 1988, 13:141-154.
49. Oakes K.D., Van der Kraak G.J. Utility of the TBARS assay in detecting oxidative stress in white sucker (Catostomus commersoni) populations exposed to pulp mill effluent. Aquat. Toxicol. 2003, 63:447-463.
50. Philip G.H., Rajasree B.H. Action of cypermethrin on tissue transamination during nitrogen metabolism in Cyprinus carpio. Ecotoxicol. Environ. Saf. 1996, 34:174-179.
51. Pimpao C.T., Zampronio A.R., de Assis H.C.S. Effects of deltamethrin on hematological parameters and enzymatic activity in Ancistrus multispinis (Pisces, Teleostei). Pest. Biochem. Physiol. 2007, 88:122-127.
52. Prieto A.I., Jos A., Pichardo S., Moreno I., Camean A.M. Differential oxidative stress responses to microcystins LR and RR in intraperitoneally exposed tilapia fish (Oreochromis sp.). Aquat. Toxicol. 2006, 77:314-321.
53. Rao J.V. Biochemical alterations in euryhaline fish, Oreochromis mossambicus exposed to sub-lethal concentrations of an organophosphorus insecticide, monocrotophos. Chemosphere 2006, 65:1814-1820.
54. Roussel H., Joachim S., Lamothe S., Palluel O., Gauthier L., Bonzom J.M. A long-term copper exposure on freshwater ecosystem using lotic mesocosms: Individual and population responses of three-spined sticklebacks (Gasterosteus aculeatus). Aquat. Toxicol. 2007, 82:272-280.
55. Soengas J.L., Aldegunde M. Energy metabolism of fish brain. Comp. Biochem. Physiol. B 2002, 131:271-296.
56. Sokal R.R., Rohlf F.J. Biometry: Principles and Practice of Statistics in Biological Research 1994, W.H.Freeman & Co Ltd, New York.
57. Song S.B., Xu Y., Zhou B.S. Effects of hexachlorobenzene on antioxidant status of liver and brain of common carp (Cyprinus carpio). Chemosphere 2006, 65:699-706.
58. Storey K.B. Oxidative stress: animal adaptations in nature. Brazilian J. Med. Biol. Res. 1996, 29:1715-1733.
59. Sturve J., Almroth B.C., Forlin L. Oxidative stress in rainbow trout (Oncorhynchus mykiss) exposed to sewage treatment plant effluent. Ecotoxicol. Environ. Saf. 2008, 70:446-452.
60. Svoboda M., Luskova V., Drastichova J., Zlabek V. The effect of diazinon on haematological indices of common carp (Cyprinus carpio L.). Acta Vet. BRNO 2001, 70:457-465.
61. Svobodova Z., Luskova V., Drastichova J., Svoboda M., Zlabek V. Effect of deltamethrin on haematological indices of common carp (Cyprinus carpio L.). Acta Vet. BRNO 2003, 72:79-85.
62. Svobodova, Z., Pravda, D., Palackova, J., 1991. Unified methods of haematological examination of fish. Research Institute of Fish Culture and Hydrobiology, Vodnany, Methods No. 20, 31 pp.
63. Velisek J., Jurcikova J., Dobsikova R., Svobodova Z., Piackova V., Machova J., Novotny L. Effects of deltamethrin on rainbow trout (Oncorhynchus mykiss). Environ. Toxicol. Pharmacol. 2007, 23:297-301.
64. Velisek J., Svobodova Z., Piackova V. Effects of 2-phenoxyethanol anaesthesia on haematological profile on common carp (Cyprinus carpio) and rainbow trout (Oncorhynchus mykiss). Acta Vet. BRNO 2007, 76:487-492.
65. White A., Fletcher T.C. Seasonal changes in serum glucose and condition of the plaice Pleuronectes platessa L. J. Fish Biol. 1985, 26:755-764.
66. Wilhelm D. Fish antioxidant defenses-a comparative approach. Brazilian J. Med. Biol. Res 1996, 29:1735-1742.
67. Zhang J.F., Shen H., Wang X.R., Wu J.C., Xue Y.Q. Effects of chronic exposure of 2,4-dichlorophenol on the antioxidant system in liver of freshwater fish Carassius auratus. Chemosphere 2004, 55:167-174.
68. Zhang X., Yang F., Zhang X., Xu Y., Liao T., Song S., Wang H. Induction of hepatic enzymes and oxidative stress in Chinese rare minnow (Gobiocypris rarus) exposed to waterborne hexabromocyclododecane (HBCDD). Aquat. Toxicol. 2008, 86:4-11.
69. Zuehlke S., Duennbier U., Heberer T. Determination of polar drug residues in sewage and surface water applying liquid chromatography-tandem mass spectrometry. Anal. Chem 2004, 76:6548-6554.