Identification by site-directed mutagenesis of a hydrophobic binding site of the mitochondrial carnitine/acylcarnitine carrier involved in the interaction with acyl groups

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1817, Issue 5, 2012, Pages 697-704

  Tonazzi, Annamaria ^a,b   Console, Lara ^a   Giangregorio, Nicola ^a,b   Indiveri, Cesare ^c   Palmieri, Ferdinando ^a,b  

^a UNIVERSITY OF BARI   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF CALABRIA   (Italy)

Author keywords

Acylcarnitine; Carnitine; Liposome; Mitochondria; Mutagenesis; Transport

Indexed keywords

ACYLCARNITINE; ANTIPORTER; CARNITINE; PROTEOLIPOSOME;

ALPHA HELIX; ARTICLE; BINDING SITE; COMPETITIVE INHIBITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN CONFORMATION; SITE DIRECTED MUTAGENESIS; STRUCTURAL HOMOLOGY;

ACYLATION; ANIMALS; BINDING SITES; CARNITINE; CARNITINE ACYLTRANSFERASES; COMPUTATIONAL BIOLOGY; ENZYME INHIBITORS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; MITOCHONDRIA; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; PALMITOYLCARNITINE; PROTEIN BINDING; RATS; TIME FACTORS;

EID: 84858719071     PISSN: 00052728     EISSN: 18792650     Source Type: Journal    
DOI: 10.1016/j.bbabio.2012.02.007     Document Type: Article

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