Site-directed mutagenesis of charged amino acids of the human mitochondrial carnitine/acylcarnitine carrier: Insight into the molecular mechanism of transport

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1797, Issue 6-7, 2010, Pages 839-845

  Giangregorio, Nicola ^a,b   Tonazzi, Annamaria ^a,b   Console, Lara ^a   Indiveri, Cesare ^c   Palmieri, Ferdinando ^a,b  

^a UNIVERSITY OF BARI   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF CALABRIA   (Italy)

Author keywords

Carnitine; Mitochondria; Mitochondrial carrier; Site directed mutagenesis; Transport

Indexed keywords

ACYLCARNITINE; ALANINE; AMINO ACID; ARGININE; ASPARTIC ACID; CARNITINE; CARRIER PROTEIN; GLUTAMIC ACID; LIPOSOME; LYSINE; MITOCHONDRIAL CARRIER; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; GENE MUTATION; HUMAN; MOLECULAR MECHANICS; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SITE DIRECTED MUTAGENESIS; WILD TYPE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITES; BIOLOGICAL TRANSPORT, ACTIVE; CARNITINE; CARNITINE ACYLTRANSFERASES; HUMANS; KINETICS; LIPOSOMES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

ESCHERICHIA COLI;

EID: 77953812442     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbabio.2010.03.017     Document Type: Article

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