Mannose-6-phosphate pathway: A review on its role in lysosomal function and dysfunction

Molecular Genetics and Metabolism

Volumn 105, Issue 4, 2012, Pages 542-550

  Coutinho, Maria Francisca ^a,b,c   Prata, Maria João ^b,c   Alves, Sandra ^a  

^a NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c Chemistry Investigation Centre (CIQ)   (Portugal)

Author keywords

GlcNAc 1 phosphotransferase; Mannose 6 phosphate receptors; Mannose 6 phosphate dependent pathway; Mucolipidosis type II (I cell disease); Mucolipidosis type III (Pseudo Hurler disease); Uncovering enzyme (UCE)

Indexed keywords

GLUCOSAMINIDASE; MANNOSE 6 PHOSPHATE; N ACETYLGALACTOSAMINE 1 PHOSPHODIESTER ALPHA N ACETYL GLUCOSAMINIDASE; SOMATOMEDIN B RECEPTOR; UNCLASSIFIED DRUG;

AMOEBA (LIFE CYCLE STAGE); CELL FUNCTION; ENZYME ACTIVITY; GENE MUTATION; GOLGI COMPLEX; HUMAN; LYSOSOME; MUCOLIPIDOSIS TYPE 2; MUCOLIPIDOSIS TYPE 3; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; REVIEW;

ANIMALS; HUMANS; LYSOSOMAL STORAGE DISEASES; LYSOSOMES; MANNOSEPHOSPHATES; SIGNAL TRANSDUCTION; TRANS-GOLGI NETWORK;

EID: 84858698808     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2011.12.012     Document Type: Review

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