Mice lacking mannose 6-phosphate uncovering enzyme activity have a milder phenotype than mice deficient for N-acetylglucosamine-1-phosphotransferase activity

Molecular Biology of the Cell

Volumn 20, Issue 20, 2009, Pages 4381-4389

  Boonen, Marielle ^a   Vogel, Peter ^b   Platt, Kenneth A ^b   Dahms, Nancy ^c   Kornfeld, Stuart ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LEXICON PHARMACEUTICALS INC   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID HYDROLASE; ALPHA N ACETYLGLUCOSAMINIDASE; CATHEPSIN D; MANNOSE 6 PHOSPHATE; MANNOSE RECEPTOR; N ACETYLGLUCOSAMINE 1 PHOSPHODIESTER ALPHA N ACETYLGLUCOSAMINIDASE; N ACETYLGLUCOSAMINE 1 PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE; SOMATOMEDIN B RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BRAIN TISSUE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME BLOOD LEVEL; ENZYME RELEASE; FIBROBLAST; GENE INACTIVATION; GENE INSERTION; GOLGI COMPLEX; HISTOPATHOLOGY; L CELL; LIVER LEVEL; LIVER PARENCHYMA; LYSOSOME; MOUSE; MUCOLIPIDOSIS TYPE 2; MUTAGENESIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

ANIMALS; BRAIN; CATHEPSIN D; ENDOCYTOSIS; FEMALE; FIBROBLASTS; GLYCOSYLATION; GOLGI APPARATUS; HYDROLASES; L CELLS (CELL LINE); LIVER; LYSOSOMES; MALE; MANNOSEPHOSPHATES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTAGENESIS, INSERTIONAL; PHENOTYPE; PHOSPHORIC DIESTER HYDROLASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR, IGF TYPE 2; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS);

MUS;

EID: 70350094393     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E09-05-0398     Document Type: Article

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