Development and Validation of a Generic Fluorescent Methyltransferase Activity Assay Based on the Transcreener AMP/GMP Assay

Journal of Biomolecular Screening

Volumn 17, Issue 1, 2012, Pages 59-70

  Klink, Tony A ^a   Staeben, Matt ^a   Kopp, Andrew L ^a   Kumar, Meera ^a   Dunn, Rebecca Schall ^a   Pinchard, Cori A ^a   Kleman Leyer, Karen M ^a   Lowery, Robert G ^a   Twesten, Kim ^b   Klumpp, Martin ^b  

^a BellBrook Labs   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; FLUORESCENT DYE; GUANOSINE PHOSPHATE; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE; S ADENOSYLHOMOCYSTEINE; SETD7 PROTEIN, HUMAN;

ANTIBODY SPECIFICITY; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; HIGH THROUGHPUT SCREENING; IMMUNOLOGY; LIMIT OF DETECTION; METABOLISM; METHODOLOGY; MOLECULAR LIBRARY; VALIDATION STUDY;

5'-GUANYLIC ACID; ADENOSINE MONOPHOSPHATE; ANTIBODY SPECIFICITY; FLUORESCENT DYES; HIGH-THROUGHPUT SCREENING ASSAYS; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; LIMIT OF DETECTION; S-ADENOSYLHOMOCYSTEINE; SMALL MOLECULE LIBRARIES;

EID: 84858628483     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057111421624     Document Type: Article

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