-
1
-
-
64349095390
-
An operational definition of epigenetics
-
S.L. Berger An operational definition of epigenetics Genes Dev. 23 2009 781 783
-
(2009)
Genes Dev.
, vol.23
, pp. 781-783
-
-
Berger, S.L.1
-
2
-
-
33847032960
-
The mammalian epigenome
-
B.E. Bernstein The mammalian epigenome Cell 128 2007 669 681
-
(2007)
Cell
, vol.128
, pp. 669-681
-
-
Bernstein, B.E.1
-
3
-
-
44649122151
-
Role of histone modifications in defining chromatin structure and function
-
K.A. Gelato, and W. Fischle Role of histone modifications in defining chromatin structure and function Biol. Chem. 389 2008 353 363
-
(2008)
Biol. Chem.
, vol.389
, pp. 353-363
-
-
Gelato, K.A.1
Fischle, W.2
-
4
-
-
36448949026
-
Multivalent engagement of chromatin modifications by linked binding modules
-
A.J. Ruthenburg Multivalent engagement of chromatin modifications by linked binding modules Nat. Rev. Mol. Cell Biol. 8 2007 983 994
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 983-994
-
-
Ruthenburg, A.J.1
-
5
-
-
59449087016
-
Histone modifying enzymes: Structures, mechanisms, and specificities
-
R. Marmorstein, and R.C. Trievel Histone modifying enzymes: structures, mechanisms, and specificities Biochim. Biophys. Acta 1789 2009 58 68
-
(2009)
Biochim. Biophys. Acta
, vol.1789
, pp. 58-68
-
-
Marmorstein, R.1
Trievel, R.C.2
-
6
-
-
33745813187
-
Reading protein modifications with interaction domains
-
B.T. Seet Reading protein modifications with interaction domains Nat. Rev. Mol. Cell Biol. 7 2006 473 483
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 473-483
-
-
Seet, B.T.1
-
7
-
-
40849139208
-
Epigenetics in cancer
-
M. Esteller Epigenetics in cancer N. Engl. J. Med. 358 2008 1148 1159
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
8
-
-
4344688693
-
Histone deacetylase inhibitors
-
P.A. Marks Histone deacetylase inhibitors Adv. Cancer Res. 91 2004 137 168
-
(2004)
Adv. Cancer Res.
, vol.91
, pp. 137-168
-
-
Marks, P.A.1
-
9
-
-
77149179080
-
Rise of the Rival
-
A. Norvell, and S.B. McMahon Rise of the Rival Science 327 2010 964 965
-
(2010)
Science
, vol.327
, pp. 964-965
-
-
Norvell, A.1
McMahon, S.B.2
-
10
-
-
57749170458
-
The many roles of histone deacetylases in development and physiology: Implications for disease and therapy
-
M. Haberland The many roles of histone deacetylases in development and physiology: implications for disease and therapy Nat. Rev. Genet. 10 2009 32 42
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 32-42
-
-
Haberland, M.1
-
11
-
-
0034632829
-
Regulation of chromatin structure by site-specific histone H3 methyltransferases
-
S. Rea Regulation of chromatin structure by site-specific histone H3 methyltransferases Nature 406 2000 593 599
-
(2000)
Nature
, vol.406
, pp. 593-599
-
-
Rea, S.1
-
12
-
-
27644589675
-
The diverse functions of histone lysine methylation
-
C. Martin, and Y. Zhang The diverse functions of histone lysine methylation Nat. Rev. Mol. Cell Biol. 6 2005 838 849
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 838-849
-
-
Martin, C.1
Zhang, Y.2
-
13
-
-
33847076849
-
Chromatin modifications and their function
-
T. Kouzarides Chromatin modifications and their function Cell 128 2007 693 705
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
14
-
-
69949148388
-
Protein methyltransferases as a target class for drug discovery
-
R.A. Copeland Protein methyltransferases as a target class for drug discovery Nat. Rev. Drug Discov. 8 2009 724 732
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 724-732
-
-
Copeland, R.A.1
-
15
-
-
36549081297
-
Chromatin-modifying proteins in cancer
-
C.K. Fog Chromatin-modifying proteins in cancer APMIS 115 2007 1060 1089
-
(2007)
APMIS
, vol.115
, pp. 1060-1089
-
-
Fog, C.K.1
-
16
-
-
23944509075
-
The SET-domain protein superfamily: Protein lysine methyltransferases
-
S.C. Dillon The SET-domain protein superfamily: protein lysine methyltransferases Genome Biol. 6 2005 227
-
(2005)
Genome Biol.
, vol.6
, pp. 227
-
-
Dillon, S.C.1
-
17
-
-
59349115177
-
Chemical mechanisms of histone lysine and arginine modifications
-
B.C. Smith, and J.M. Denu Chemical mechanisms of histone lysine and arginine modifications Biochim. Biophys. Acta 1789 2009 45 57
-
(2009)
Biochim. Biophys. Acta
, vol.1789
, pp. 45-57
-
-
Smith, B.C.1
Denu, J.M.2
-
18
-
-
65249151919
-
Structure and function of histone methylation binding proteins
-
M.A. Adams-Cioaba, and J. Min Structure and function of histone methylation binding proteins Biochem. Cell Biol. 87 2009 93 105
-
(2009)
Biochem. Cell Biol.
, vol.87
, pp. 93-105
-
-
Adams-Cioaba, M.A.1
Min, J.2
-
19
-
-
34249048369
-
L3MBTL1, a histone-methylation-dependent chromatin lock
-
P. Trojer L3MBTL1, a histone-methylation-dependent chromatin lock Cell 129 2007 915 928
-
(2007)
Cell
, vol.129
, pp. 915-928
-
-
Trojer, P.1
-
20
-
-
41849100358
-
Beyond histone methyl-lysine binding: How malignant brain tumor (MBT) protein L3MBTL1 impacts chromatin structure
-
P. Trojer, and D. Reinberg Beyond histone methyl-lysine binding: how malignant brain tumor (MBT) protein L3MBTL1 impacts chromatin structure Cell Cycle 7 2008 578 585
-
(2008)
Cell Cycle
, vol.7
, pp. 578-585
-
-
Trojer, P.1
Reinberg, D.2
-
21
-
-
77449127237
-
Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases
-
J.R. Horton Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases Nat. Struct. Mol. Biol. 17 2010 38 43
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 38-43
-
-
Horton, J.R.1
-
22
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
Y. Shi Histone demethylation mediated by the nuclear amine oxidase homolog LSD1 Cell 119 2004 941 953
-
(2004)
Cell
, vol.119
, pp. 941-953
-
-
Shi, Y.1
-
23
-
-
17644392469
-
Methylation: Lost in hydroxylation?
-
S.C. Trewick Methylation: lost in hydroxylation? EMBO Rep. 6 2005 315 320
-
(2005)
EMBO Rep.
, vol.6
, pp. 315-320
-
-
Trewick, S.C.1
-
24
-
-
73449105394
-
Structure-activity analysis of semisynthetic nucleosomes: Mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B
-
R.K. McGinty Structure-activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B ACS Chem. Biol. 4 2009 958 968
-
(2009)
ACS Chem. Biol.
, vol.4
, pp. 958-968
-
-
McGinty, R.K.1
-
25
-
-
2642551574
-
Small molecule regulators of protein arginine methyltransferases
-
D. Cheng Small molecule regulators of protein arginine methyltransferases J. Biol. Chem. 279 2004 23892 23899
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 23892-23899
-
-
Cheng, D.1
-
26
-
-
33846783261
-
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase
-
S. Kubicek Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase Mol. Cell 25 2007 473 481
-
(2007)
Mol. Cell
, vol.25
, pp. 473-481
-
-
Kubicek, S.1
-
27
-
-
77952361615
-
A chemiluminescence-based method for identification of histone lysine methyltransferase inhibitors
-
10.1039/B921912A
-
A.M. Quinn A chemiluminescence-based method for identification of histone lysine methyltransferase inhibitors Mol. BioSyst. 2010 10.1039/B921912A
-
(2010)
Mol. BioSyst.
-
-
Quinn, A.M.1
-
28
-
-
77955399089
-
Accessing protein methyltransferase and demethylase enzymology using microfluidic capillary electrophoresis
-
T.J. Wigle Accessing protein methyltransferase and demethylase enzymology using microfluidic capillary electrophoresis Chem. Biol. 17 2010 695 704
-
(2010)
Chem. Biol.
, vol.17
, pp. 695-704
-
-
Wigle, T.J.1
-
29
-
-
21244475895
-
Avidin plate assay system for enzymatic characterization of a histone lysine methyltransferase
-
H. Gowher Avidin plate assay system for enzymatic characterization of a histone lysine methyltransferase Anal. Biochem. 342 2005 287 291
-
(2005)
Anal. Biochem.
, vol.342
, pp. 287-291
-
-
Gowher, H.1
-
30
-
-
74049085886
-
A continuous protein methyltransferase (G9a) assay for enzyme activity measurement and inhibitor screening
-
A. Dhayalan A continuous protein methyltransferase (G9a) assay for enzyme activity measurement and inhibitor screening J. Biomol. Screen. 14 2009 1129 1133
-
(2009)
J. Biomol. Screen.
, vol.14
, pp. 1129-1133
-
-
Dhayalan, A.1
-
31
-
-
20444414511
-
A coupled fluorescent assay for histone methyltransferases
-
E. Collazo A coupled fluorescent assay for histone methyltransferases Anal. Biochem. 342 2005 86 92
-
(2005)
Anal. Biochem.
, vol.342
, pp. 86-92
-
-
Collazo, E.1
-
32
-
-
0842303035
-
An enzyme-coupled colorimetric assay for S-adenosylmethionine-dependent methyltransferases
-
C.L. Hendricks An enzyme-coupled colorimetric assay for S-adenosylmethionine-dependent methyltransferases Anal. Biochem. 326 2004 100 105
-
(2004)
Anal. Biochem.
, vol.326
, pp. 100-105
-
-
Hendricks, C.L.1
-
33
-
-
33644672263
-
An enzyme-coupled continuous spectrophotometric assay for S-adenosylmethionine-dependent methyltransferases
-
K.M. Dorgan An enzyme-coupled continuous spectrophotometric assay for S-adenosylmethionine-dependent methyltransferases Anal. Biochem. 350 2006 249 255
-
(2006)
Anal. Biochem.
, vol.350
, pp. 249-255
-
-
Dorgan, K.M.1
-
34
-
-
0034326785
-
A spectrophotometric method for determining the oxidative deamination of methylamine by the amine oxidases
-
J.M. Lizcano A spectrophotometric method for determining the oxidative deamination of methylamine by the amine oxidases Anal. Biochem. 286 2000 75 79
-
(2000)
Anal. Biochem.
, vol.286
, pp. 75-79
-
-
Lizcano, J.M.1
-
35
-
-
75749150081
-
A miniaturized screen for inhibitors of Jumonji histone demethylases
-
M. Sakurai A miniaturized screen for inhibitors of Jumonji histone demethylases Mol. Biosyst. 6 2010 357 364
-
(2010)
Mol. Biosyst.
, vol.6
, pp. 357-364
-
-
Sakurai, M.1
-
36
-
-
16344368814
-
Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process
-
F. Forneris Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process FEBS Lett. 579 2005 2203 2207
-
(2005)
FEBS Lett.
, vol.579
, pp. 2203-2207
-
-
Forneris, F.1
-
37
-
-
34249934238
-
Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes
-
Y. Huang Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes Proc. Natl. Acad. Sci. U. S. A. 104 2007 8023 8028
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 8023-8028
-
-
Huang, Y.1
-
38
-
-
77949874334
-
Combinatorial profiling of chromatin binding modules reveals multisite discrimination
-
A.L. Garske Combinatorial profiling of chromatin binding modules reveals multisite discrimination Nat. Chem. Biol. 6 2010 283 290
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 283-290
-
-
Garske, A.L.1
-
39
-
-
1042276983
-
Assays for the determination of structure and dynamics of the interaction of the chromodomain with histone peptides
-
S.A. Jacobs Assays for the determination of structure and dynamics of the interaction of the chromodomain with histone peptides Methods Enzymol. 376 2004 131 148
-
(2004)
Methods Enzymol.
, vol.376
, pp. 131-148
-
-
Jacobs, S.A.1
-
40
-
-
36849095082
-
L3MBTL1 recognition of mono- and dimethylated histones
-
J. Min L3MBTL1 recognition of mono- and dimethylated histones Nat. Struct. Mol. Biol. 14 2007 1229 1230
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 1229-1230
-
-
Min, J.1
-
41
-
-
36249026356
-
Structural basis for lower lysine methylation state-specific readout by MBT repeats of L3MBTL1 and an engineered PHD finger
-
H. Li Structural basis for lower lysine methylation state-specific readout by MBT repeats of L3MBTL1 and an engineered PHD finger Mol. Cell 28 2007 677 691
-
(2007)
Mol. Cell
, vol.28
, pp. 677-691
-
-
Li, H.1
-
42
-
-
51349162460
-
The malignant brain tumor repeats of human SCML2 bind to peptides containing monomethylated lysine
-
C.M. Santiveri The malignant brain tumor repeats of human SCML2 bind to peptides containing monomethylated lysine J. Mol. Biol. 382 2008 1107 1112
-
(2008)
J. Mol. Biol.
, vol.382
, pp. 1107-1112
-
-
Santiveri, C.M.1
-
43
-
-
77949351403
-
Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: An AlphaScreen-based assay for antagonists of methyl-lysine binding proteins
-
T.J. Wigle Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteins J. Biomol. Screen. 15 2010 62 71
-
(2010)
J. Biomol. Screen.
, vol.15
, pp. 62-71
-
-
Wigle, T.J.1
-
44
-
-
77951161223
-
A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics
-
A.M. Quinn A homogeneous method for investigation of methylation- dependent protein-protein interactions in epigenetics Nucleic Acids Res. 38 2010 e11
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 11
-
-
Quinn, A.M.1
-
45
-
-
55949109901
-
Cancer treatment of the future: Inhibitors of histone methyltransferases
-
A. Spannhoff Cancer treatment of the future: inhibitors of histone methyltransferases Int. J. Biochem. Cell Biol. 41 2009 4 11
-
(2009)
Int. J. Biochem. Cell Biol.
, vol.41
, pp. 4-11
-
-
Spannhoff, A.1
-
46
-
-
70349780606
-
The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors
-
A. Spannhoff The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors ChemMedChem 4 2009 1568 1582
-
(2009)
ChemMedChem
, vol.4
, pp. 1568-1582
-
-
Spannhoff, A.1
-
47
-
-
55549140173
-
Role of the histone H3 Lysine 4 methyltransferase, SET7/9, in the regulation of NF-{kappa}B-dependent inflammatory genes: Relevance to diabetes and inflammation
-
Y. Li Role of the histone H3 Lysine 4 methyltransferase, SET7/9, in the regulation of NF-{kappa}B-dependent inflammatory genes: relevance to diabetes and inflammation J. Biol. Chem. 283 2008 26771 26781
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 26771-26781
-
-
Li, Y.1
-
48
-
-
74249105659
-
Essential role of the histone methyltransferase G9a in cocaine-induced plasticity
-
I. Maze Essential role of the histone methyltransferase G9a in cocaine-induced plasticity Science 327 2010 213 216
-
(2010)
Science
, vol.327
, pp. 213-216
-
-
Maze, I.1
-
49
-
-
71149121303
-
Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex
-
A. Schaefer Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex Neuron 64 2009 678 691
-
(2009)
Neuron
, vol.64
, pp. 678-691
-
-
Schaefer, A.1
-
50
-
-
33645751058
-
Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state
-
K.M. McGarvey Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state Cancer Res. 66 2006 3541 3549
-
(2006)
Cancer Res.
, vol.66
, pp. 3541-3549
-
-
McGarvey, K.M.1
-
51
-
-
44249128891
-
Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells
-
Y. Kondo Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells PLoS One 3 2008 e2037
-
(2008)
PLoS One
, vol.3
, pp. 2037
-
-
Kondo, Y.1
-
52
-
-
77951233574
-
G9A and GLP methylate lysine 373 in the tumor suppressor p53
-
J. Huang G9A and GLP methylate lysine 373 in the tumor suppressor p53 J. Biol. Chem. 285 2010 9636
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 9636
-
-
Huang, J.1
-
53
-
-
51949111451
-
Chemical probes for histone-modifying enzymes
-
P.A. Cole Chemical probes for histone-modifying enzymes Nat. Chem. Biol. 4 2008 590 597
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 590-597
-
-
Cole, P.A.1
-
54
-
-
30644474460
-
Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9
-
D. Greiner Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9 Nat. Chem. Biol. 1 2005 143 145
-
(2005)
Nat. Chem. Biol.
, vol.1
, pp. 143-145
-
-
Greiner, D.1
-
55
-
-
77953691195
-
Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases
-
Y. Chang Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases J. Mol. Biol. 400 2010 1 7
-
(2010)
J. Mol. Biol.
, vol.400
, pp. 1-7
-
-
Chang, Y.1
-
56
-
-
77955363182
-
Protein lysine methyltransferase G9a inhibitors: Design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines
-
F. Liu Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy- quinazolines J. Med. Chem. 9 2010 5844 5857
-
(2010)
J. Med. Chem.
, vol.9
, pp. 5844-5857
-
-
Liu, F.1
-
57
-
-
73249124141
-
Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a
-
F. Liu Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a J. Med. Chem. 52 2009 7950 7953
-
(2009)
J. Med. Chem.
, vol.52
, pp. 7950-7953
-
-
Liu, F.1
-
58
-
-
78649907647
-
-
For the latest unpublished progress in this area, see
-
For the latest unpublished progress in this area, see: http://www.thesgc.org/chemical-probes/UNC0638/#overview
-
-
-
-
59
-
-
62049083789
-
Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294
-
Y. Chang Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294 Nat. Struct. Mol. Biol. 16 2009 312 317
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 312-317
-
-
Chang, Y.1
-
60
-
-
77249142404
-
The art of the chemical probe
-
S.V. Frye The art of the chemical probe Nat. Chem. Biol. 6 2010 159 161
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 159-161
-
-
Frye, S.V.1
-
61
-
-
55949136562
-
Roles of the EZH2 histone methyltransferase in cancer epigenetics
-
J.A. Simon, and C.A. Lange Roles of the EZH2 histone methyltransferase in cancer epigenetics Mutat. Res. 647 2008 21 29
-
(2008)
Mutat. Res.
, vol.647
, pp. 21-29
-
-
Simon, J.A.1
Lange, C.A.2
-
62
-
-
0034912742
-
Histone acetyltransferases
-
S.Y. Roth Histone acetyltransferases Annu. Rev. Biochem. 70 2001 81 120
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 81-120
-
-
Roth, S.Y.1
-
63
-
-
0035313803
-
Histone acetyltransferases: Function, structure, and catalysis
-
R. Marmorstein, and S.Y. Roth Histone acetyltransferases: function, structure, and catalysis Curr. Opin. Genet. Dev. 11 2001 155 161
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 155-161
-
-
Marmorstein, R.1
Roth, S.Y.2
-
65
-
-
33846122993
-
Dimethyl sulfoxide to vorinostat: Development of this histone deacetylase inhibitor as an anticancer drug
-
P. Marks, and R. Breslow Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug Nat. Biotechnol. 25 2007 84 90
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 84-90
-
-
Marks, P.1
Breslow, R.2
-
66
-
-
77950640292
-
Inhibitors of HDACs-effective drugs against cancer?
-
S. Müller, and H. Krämer Inhibitors of HDACs-effective drugs against cancer? Current Cancer Drug Targets 10 2010 210 228
-
(2010)
Current Cancer Drug Targets
, vol.10
, pp. 210-228
-
-
Müller, S.1
Krämer, H.2
-
67
-
-
33748451151
-
Anticancer activities of histone deacetylase inhibitors
-
J.E. Bolden Anticancer activities of histone deacetylase inhibitors Nat. Rev. Drug. Discov. 5 2006 769 784
-
(2006)
Nat. Rev. Drug. Discov.
, vol.5
, pp. 769-784
-
-
Bolden, J.E.1
-
68
-
-
33947313218
-
HDACs, histone deacetylation and gene transcription: From molecular biology to cancer therapeutics
-
P. Gallinari HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics Cell Res. 17 2007 195 211
-
(2007)
Cell Res.
, vol.17
, pp. 195-211
-
-
Gallinari, P.1
-
69
-
-
0033609055
-
Three proteins define a class of human histone deacetylases related to yeast Hda1p
-
C.M. Grozinger Three proteins define a class of human histone deacetylases related to yeast Hda1p Proc. Natl. Acad. Sci. U. S. A. 96 1999 4868 4873
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 4868-4873
-
-
Grozinger, C.M.1
-
70
-
-
0036479127
-
Molecular cloning and characterization of a novel histone deacetylase HDAC10
-
A.R. Guardiola, and T.P. Yao Molecular cloning and characterization of a novel histone deacetylase HDAC10 J. Biol. Chem. 277 2002 3350 3356
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3350-3356
-
-
Guardiola, A.R.1
Yao, T.P.2
-
71
-
-
0037161744
-
HDAC6 is a microtubule-associated deacetylase
-
C. Hubbert HDAC6 is a microtubule-associated deacetylase Nature 417 2002 455 458
-
(2002)
Nature
, vol.417
, pp. 455-458
-
-
Hubbert, C.1
-
72
-
-
21144444486
-
HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor
-
J. Kovacs HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor Mol. Cell 18 2005 601 607
-
(2005)
Mol. Cell
, vol.18
, pp. 601-607
-
-
Kovacs, J.1
-
73
-
-
43849103348
-
High-throughput assays for sirtuin enzymes: A microfluidic mobility shift assay and a bioluminescence assay
-
Y. Liu High-throughput assays for sirtuin enzymes: a microfluidic mobility shift assay and a bioluminescence assay Anal. Biochem. 378 2008 53 59
-
(2008)
Anal. Biochem.
, vol.378
, pp. 53-59
-
-
Liu, Y.1
-
74
-
-
23944515293
-
In vitro assays for the determination of histone deacetylase activity
-
B. Heltweg In vitro assays for the determination of histone deacetylase activity Methods 36 2005 332 337
-
(2005)
Methods
, vol.36
, pp. 332-337
-
-
Heltweg, B.1
-
75
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
K.T. Howitz Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan Nature 425 2003 191 196
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
-
76
-
-
20444444649
-
Mechanism of human SIRT1 activation by resveratrol
-
M.T. Borra Mechanism of human SIRT1 activation by resveratrol J. Biol. Chem. 280 2005 17187 17195
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17187-17195
-
-
Borra, M.T.1
-
77
-
-
77950246109
-
SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1
-
M. Pacholec SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1 J. Biol. Chem. 285 2010 8340 8351
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 8340-8351
-
-
Pacholec, M.1
-
78
-
-
20444431507
-
Substrate-specific activation of sirtuins by resveratrol
-
M Kaeberlein Substrate-specific activation of sirtuins by resveratrol J. Biol. Chem. 280 2005 17038 17045
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17038-17045
-
-
Kaeberlein, M.1
-
79
-
-
43049119236
-
The use of diversity profiling to characterize chemical modulators of the histone deacetylases
-
L. Blackwell The use of diversity profiling to characterize chemical modulators of the histone deacetylases Life Sci. 82 2008 1050 1058
-
(2008)
Life Sci.
, vol.82
, pp. 1050-1058
-
-
Blackwell, L.1
|