Microarray analysis of the global gene expression profile following hypothermia and transient focal cerebral ischemia

Neuroscience

Volumn 208, Issue , 2012, Pages 109-122

  Nagel, S ^a   Papadakis, M ^b   Pfleger, K ^a   Grond Ginsbach, C ^a   Buchan, A M ^b   Wagner, S ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Apoptosis; Canonical pathways; Hypothermia; MCAO; Microarray; Networks

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INFARCTION SIZE; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE REPRESSION; HIG 1 GENE; HNRNPAB GENE; INDUCED HYPOTHERMIA; JAK3 GENE; MALE; MICROARRAY ANALYSIS; NEUROPROTECTION; NEUROSCORE; NONHUMAN; PRIORITY JOURNAL; RAT; SCORING SYSTEM; TRANSIENT ISCHEMIC ATTACK; UPREGULATION;

ANIMALS; APOPTOSIS; BODY TEMPERATURE; DATABASES, GENETIC; DOWN-REGULATION; GENE EXPRESSION PROFILING; HEMODYNAMICS; HYPOTHERMIA, INDUCED; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; MAGNETIC RESONANCE IMAGING; MALE; MICROARRAY ANALYSIS; NEURAL PATHWAYS; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; REPERFUSION; REPRODUCIBILITY OF RESULTS; RNA; SOFTWARE; UP-REGULATION;

EID: 84858620587     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.01.048     Document Type: Article

References (51)

1. Aoki M., Tamatani M., Taniguchi M., Yamaguchi A., Bando Y., Kasai K., Miyoshi Y., Nakamura Y., Vitek M.P., Tohyama M., Tanaka H., Sugimoto H. Hypothermic treatment restores glucose regulated protein 78 (GRP78) expression in ischemic brain. Brain Res Mol Brain Res 2001, 95:117-128.
2. Bar-Peled O., Korkotian E., Segal M., Groner Y. Constitutive overexpression of Cu/Zn superoxide dismutase exacerbates kainic acid-induced apoptosis of transgenic-Cu/Zn superoxide dismutase neurons. Proc Natl Acad Sci U S A 1996, 93:8530-8535.
3. Bedo G., Vargas M., Ferreiro M.J., Chalar C., Agrati D. Characterization of hypoxia induced gene 1: expression during rat central nervous system maturation and evidence of antisense RNA expression. Int J Dev Biol 2005, 49:431-436.
4. Belfort G.M., Kandror K.V. Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells. J Biol Chem 2003, 278:47971-47978.
5. Bernard S.A., Gray T.W., Buist M.D., Jones B.M., Silvester W., Gutteridge G., Smith K. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 2002, 346:557-563.
6. Bernardo A., Harrison F.E., McCord M., Zhao J., Bruchey A., Davies S.S., Jackson Roberts L., Mathews P.M., Matsuoka Y., Ariga T., Yu R.K., Thompson R., McDonald M.P. Elimination of GD3 synthase improves memory and reduces amyloid-beta plaque load in transgenic mice. Neurobiol Aging 2009, 30:1777-1791.
7. Brigidi G.S., Bamji S.X. Cadherin-catenin adhesion complexes at the synapse. Curr Opin Neurobiol 2011, 21:208-214.
8. Den Hertog H.M., van der Worp H.B., Tseng M.C., Dippel D.W. Cooling therapy for acute stroke. Cochrane Database Syst Rev 2009, CD001247.
9. Felger J.C., Abe T., Kaunzner U.W., Gottfried-Blackmore A., Gal-Toth J., McEwen B.S., Iadecola C., Bulloch K. Brain dendritic cells in ischemic stroke: time course, activation state, and origin. Brain Behav Immun 2010, 24:724-737.
10. Garcia J.H., Wagner S., Liu K.F., Hu X.J. Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Stroke 1995, 26:627-635.
11. Garcia J.H., Yoshida Y., Chen H. Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat. Am J Pathol 1993, 142:623-635.
12. Gaspar E., Hardenbicker C., Bodo E., Wenzel B., Ramot Y., Funk W., Kromminga A., Paus R. Thyrotropin releasing hormone (TRH): a new player in human hair-growth control. FASEB J 2010, 24:393-403.
13. He Y., Smith R. Nuclear functions of heterogeneous nuclear ribonucleoproteins A/B. Cell Mol Life Sci 2009, 66:1239-1256.
14. Hwang P.M., Bunz F., Yu J., Rago C., Chan T.A., Murphy M.P., Kelso G.F., Smith R.A., Kinzler K.W., Vogelstein B. Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Nat Med 2001, 7:1111-1117.
15. Jin K., Mao X.O., Eshoo M.W., del Rio G., Rao R., Chen D., Simon R.P., Greenberg D.A. cDNA microarray analysis of changes in gene expression induced by neuronal hypoxia in vitro. Neurochem Res 2002, 27:1105-1112.
16. Kallmunzer B., Kollmar R. Temperature management in stroke-an unsolved, but important topic. Cerebrovasc Dis 2011, 31:532-543.
17. Kapoor N., Gupta R., Menon S.T., Folta-Stogniew E., Raleigh D.P., Sakmar T.P. Nucleobindin 1 is a calcium-regulated guanine nucleotide dissociation inhibitor of G{alpha}i1. J Biol Chem 2010, 285:31647-31660.
18. Kim H.L., Cassone M., Otvos L., Vogiatzi P. HIF-1alpha and STAT3 client proteins interacting with the cancer chaperone Hsp90: therapeutic considerations. Cancer Biol Ther 2008, 7:10-14.
19. Kim J.B., Piao C.S., Lee K.W., Han P.L., Ahn J.I., Lee Y.S., Lee J.K. Delayed genomic responses to transient middle cerebral artery occlusion in the rat. J Neurochem 2004, 89:1271-1282.
20. Kobayashi M.S., Asai S., Ishikawa K., Nishida Y., Nagata T., Takahashi Y. Global profiling of influence of intra-ischemic brain temperature on gene expression in rat brain. Brain Res Rev 2008, 58:171-191.
21. Kroes R.A., He H., Emmett M.R., Nilsson C.L., Leach F.E., Amster I.J., Marshall A.G., Moskal J.R. Overexpression of ST6GalNAcV, a ganglioside-specific alpha2,6-sialyltransferase, inhibits glioma growth in vivo. Proc Natl Acad Sci U S A 2010, 107:12646-12651.
22. Lin C.Y., Li C.C., Huang P.H., Lee F.J. A developmentally regulated ARF-like 5 protein (ARL5), localized to nuclei and nucleoli, interacts with heterochromatin protein 1. J Cell Sci 2002, 115:4433-4445.
23. Lluis J.M., Llacuna L., von Montfort C., Bárcena C., Enrich C., Morales A., Fernandez-Checa J.C. GD3 synthase overexpression sensitizes hepatocarcinoma cells to hypoxia and reduces tumor growth by suppressing the cSrc/NF-kappaB survival pathway. PLoS One 2009, 4:e8059.
24. Longa E.Z., Weinstein P.R., Carlson S., Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989, 20:84-91.
25. Lu A., Ran R., Parmentier-Batteur S., Nee A., Sharp F.R. Geldanamycin induces heat shock proteins in brain and protects against focal cerebral ischemia. J Neurochem 2002, 81:355-364.
26. Lu A., Tang Y., Ran R., Clark J.F., Aronow B.J., Sharp F.R. Genomics of the periinfarction cortex after focal cerebral ischemia. J Cereb Blood Flow Metab 2003, 23:786-810.
27. Lu X.C., Williams A.J., Yao C., Berti R., Hartings J.A., Whipple R., Vahey M.T., Polavarapu R.G., Woller K.L., Tortella F.C., Dave J.R. Microarray analysis of acute and delayed gene expression profile in rats after focal ischemic brain injury and reperfusion. J Neurosci Res 2004, 77:843-857.
28. Macleod M.R., Petersson J., Norrving B., Hacke W., Dirnagl U., Wagner M., Schwab S. Hypothermia for stroke: call to action 2010. Int J Stroke 2010, 5:489-492.
29. Masuo Y., Ogura A., Kobayashi M., Masaki T., Furuta Y., Ono T., Takamatsu K. Hippocalcin protects hippocampal neurons against excitotoxin damage by enhancing calcium extrusion. Neuroscience 2007, 145:495-504.
30. Matsuda Y., Nara K., Watanabe Y., Saito T., Sanai Y. Chromosome mapping of the GD3 synthase gene (SIAT8) in human and mouse. Genomics 1996, 32:137-139.
31. Mitsios N., Saka M., Krupinski J., Pennucci R., Sanfeliu C., Wang Q., Rubio F., Gaffney J., Kumar P., Kumar S., Sullivan M., Slevin M. A microarray study of gene and protein regulation in human and rat brain following middle cerebral artery occlusion. BMC Neurosci 2007, 8:93.
32. Murotomi K., Takagi N., Takeo S., Tanonaka K. NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion. Mol Cell Neurosci 2011, 46:681-688.
33. Nagata T., Takahashi Y., Sugahara M., Murata A., Nishida Y., Ishikawa K., Asai S. Profiling of genes associated with transcriptional responses in mouse hippocampus after transient forebrain ischemia using high-density oligonucleotide DNA array. Brain Res Mol Brain Res 2004, 121:1-11.
34. Nagel S., Papadakis M., Hoyte L., Buchan A.M. Therapeutic hypothermia in experimental models of focal and global cerebral ischemia and intracerebral hemorrhage. Expert Rev Neurother 2008, 8:1255-1268.
35. Ning M., Sarracino D.A., Kho A.T., Guo S., Lee S.R., Krastins B., Buonanno F.S., Vizcaino J.A., Orchard S., McMullin D., Wang X., Lo E.H. Proteomic temporal profile of human brain endothelium after oxidative stress. Stroke 2011, 42:37-43.
36. Ohta H., Terao Y., Shintani Y., Kiyota Y. Therapeutic time window of post-ischemic mild hypothermia and the gene expression associated with the neuroprotection in rat focal cerebral ischemia. Neurosci Res 2007, 57:424-433.
37. Ojika K., Ueki Y., Mitake S., Tsugu Y., Otsuka Y., Katada E. Demonstration of the biological activity of peptide fragments related to human and rat hippocampal cholinergic neurostimulating peptide (HCNP). Neurosci Lett 1996, 215:127-130.
38. Okumura H., Ishii H., Pichiorri F., Croce C.M., Mori M., Huebner K. Fragile gene product, Fhit, in oxidative and replicative stress responses. Cancer Sci 2009, 100:1145-1150.
39. Orellana D.I., Quintanilla R.A., Gonzalez-Billault C., Maccioni R.B. Role of the JAKs/STATs pathway in the intracellular calcium changes induced by interleukin-6 in hippocampal neurons. Neurotox Res 2005, 8:295-304.
40. Percipalle P., Raju C.S., Fukuda N. Actin-associated hnRNP proteins as transacting factors in the control of mRNA transport and localization. RNA Biol 2009, 6:171-174.
41. Qin H.P., Mei G.H., Wei L., Jiang J.Y. Effect of profound hypothermia on genomics of hippocampus following complete cerebral ischemia in rats. Neurol Res 2008, 30:536-541.
42. Rambaratsingh R.A., Stone J.C., Blumberg P.M., Lorenzo P.S. RasGRP1 represents a novel non-protein kinase C phorbol ester signaling pathway in mouse epidermal keratinocytes. J Biol Chem 2003, 278:52792-52801.
43. Shankaran S., Laptook A.R., Ehrenkranz R.A., Tyson J.E., McDonald S.A., Donovan E.F., Fanaroff A.A., Poole W.K., Wright L.L., Higgins R.D., Finer N.N., Carlo W.A., Duara S., Oh W., Cotten C.M., Stevenson D.K., Stoll B.J., Lemons J.A., Guillet R., Jobe A.H. Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med 2005, 353:1574-1584.
44. Tay A.S., Hu L.F., Lu M., Wong P.T., Bian J.S. Hydrogen sulfide protects neurons against hypoxic injury via stimulation of ATP-sensitive potassium channel/protein kinase C/extracellular signal-regulated kinase/heat shock protein 90 pathway. Neuroscience 2010, 167:277-286.
45. Trieu V.N., Liu R., Liu X.P., Uckun F.M. A specific inhibitor of Janus kinase-3 increases survival in a transgenic mouse model of amyotrophic lateral sclerosis. Biochem Biophys Res Commun 2000, 267:22-25.
46. Vallentin A., Lo T.C., Joubert D. A single point mutation in the V3 region affects protein kinase Calpha targeting and accumulation at cell-cell contacts. Mol Cell Biol 2001, 21:3351-3363.
47. van der Worp H.B., Macleod M.R., Kollmar R. Therapeutic hypothermia for acute ischemic stroke: ready to start large randomized trials?. J Cereb Blood Flow Metab 2010, 30:1079-1093.
48. van der Worp H.B., Sena E.S., Donnan G.A., Howells D.W., Macleod M.R. Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis. Brain 2007, 130:3063-3074.
49. Wen X.R., Li C., Zong Y.Y., Yu C.Z., Xu J., Han D., Zhang G.Y. Dual inhibitory roles of geldanamycin on the c-Jun NH2-terminal kinase 3 signal pathway through suppressing the expression of mixed-lineage kinase 3 and attenuating the activation of apoptosis signal-regulating kinase 1 via facilitating the activation of Akt in ischemic brain injury. Neuroscience 2008, 156:483-497.
50. Yamaguchi A., Hori O., Stern D.M., Hartmann E., Ogawa S., Tohyama M. Stress-associated endoplasmic reticulum protein 1 (SERP1)/ribosome-associated membrane protein 4 (RAMP4) stabilizes membrane proteins during stress and facilitates subsequent glycosylation. J Cell Biol 1999, 147:1195-1204.
51. Yu P., Chen Y., Tagle D.A., Cai T. PJA1, encoding a RING-H2 finger ubiquitin ligase, is a novel human X chromosome gene abundantly expressed in brain. Genomics 2002, 79:869-874.