A developmentally regulated ARF-like 5 protein (ARL5), localized to nuclei and nucleoli, interacts with heterochromatin protein 1

Journal of Cell Science

Volumn 115, Issue 23, 2002, Pages 4433-4445

  Lin, Ching Y ^a   Li, Chun Chun ^a   Huang, Pei Hsin ^a   Lee, Fang Jen S ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

ADP ribosylation factors; Embryonic development; Heterochromatin; HP1 ; Importin ; Myristoylation

Indexed keywords

CHROMOSOME PROTEIN; COMPLEMENTARY DNA; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; KARYOPHERIN ALPHA; MESSENGER RNA; MUTANT PROTEIN; NUCLEOTIDE; PROTEIN ARL5; PROTEIN HP1ALPHA; RAS PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CELL STRAIN COS7; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO DEVELOPMENT; GENE OVEREXPRESSION; HETEROCHROMATIN; HUMAN; IMMUNOPRECIPITATION; IN VITRO STUDY; LIVER; MAMMAL CELL; MOLECULAR CLONING; MOLECULAR DYNAMICS; MOUSE; MYRISTYLATION; NONHUMAN; NUCLEOLUS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; STRUCTURAL HOMOLOGY; TELOMERE; TWO HYBRID SYSTEM; YEAST;

ADP-RIBOSYLATION FACTORS; AMINO ACID SEQUENCE; ANIMALS; CELL NUCLEOLUS; CELL NUCLEUS; CHROMOSOMAL PROTEINS, NON-HISTONE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; MYRISTIC ACID; ORGAN SPECIFICITY; PROTEIN BINDING; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID;

ANIMALIA; MAMMALIA;

EID: 0036903977     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.00123     Document Type: Review

References (59)

1. Ball, L. J., Murzina, N. V., Broadhurst, R. W., Raine, A. R., Archer, S. J., Stott, E. J., Murzin, A. G., Singh, P. B., Domaille, P. J. and Laue, E. D. (1997) Structure of the chromatin binding (chromo) domain from mouse modifier protein 1. EMBO J. 16, 2473-2481.
2. Bobak, D. A., Nightingale, M. S., Murtagh, J. J., Price, S. R., Moss, J. and Vaughan, M. (1989). Molecular cloning, characterization, and expression of human ADP-ribosylation factors: two guanine nucleotide-dependent activators of cholera toxin. Proc. Natl. Acad. Sci. USA 86, 6101-6105.
3. Boman, A. L. and Kahn, R. A. (1995). Arf proteins: the membrane traffic police? Trends Biochem. Sci. 20, 147-150.
4. Brasher, S. V., Smith, B. O., Fogh, R. H., Nietlispach, D., Thiru, A., Nielsen, P. R., Broadhurst, R. W., Ball, L. J., Murzina, N. V. and Laue, E. D. (2000) The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer. EMBO J. 19, 1587-1597.
5. Cavenagh, M. M., Breiner, M., Schurmann, A., Rosenwald, A. G., Terui, T., Zhang, C.-j., Randazzo, P. A., Adams, M., Joost, H.-G. and Kahn, R. A. (1994). ADP-ribosylation factor (ARF)-like 3, a new member of the ARF family of GTP-binding proteins cloned from human and rat tissues. J. Biol. Chem. 269, 18937-18942.
6. Clark, J., Moore, L., Krasinskas, A., Way, J., Batttey, J., Tamkun, J. and Kahn, R. A. (1993). Selective amplification of additional members of the ADP-ribosylation factor (ARF) family: cloning of additional human and Drosophila ARF-like genes. Proc. Natl. Acad. Sci. USA 90, 8952-8956.
7. Cuomo, C. A., Kirch, S. A., Gyuris, J., Brent, R. and Oettinger, M. A. (1994). Rch1, a protein that specifically interacts with the RAG-1 recombination-activating protein. Proc. Natl. Acad. Sci. USA 91, 6156-6160.
8. Dascher, C. and Balch, W. E. (1994). Dominant inhibitory mutants of ARF1 block endoplasmic reticulum to Golgi transport and trigger disassembly of the Golgi apparatus. J. Biol. Chem. 269, 1437-1448.
9. Eissenberg, J. C. and Elgin, S. C. (2000). The HP1 protein family: getting a grip on chromatin. Curr. Opin. Genet. Dev. 10, 204-210.
10. Eissenberg, J. C., James, T. C., Foster-Harnett, D. M., Harnett, T., Ngan, V. and Elgin, S. C. (1990). Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 87, 9923-9927.
11. Elgin, S. C. (1996). Heterochromatin and gene regulation in Drosophila. Curr. Opin. Genet. Dev. 6. 193-202.
12. Fanti, L., Giovinazzo, G., Berloco, M. and Pimpinelli, S. (1998). The heterochromatin protein 1 prevents telomere fusions in Drosophila. Mol. Cell 2, 527-538.
13. Frank, S., Upender, S., Hansen, S. H. and Casanova, J. E. (1998). ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6. J. Biol. Chem. 273, 23-27.
14. Gant, T. M. and Wilson, K. L. (1997). Nuclear assembly. Annu. Rev. Cell Dev. Biol. 13, 669-695.
15. Garcia, S. N. and Pillus, L. (1999). Net results of nucleolar dynamics. Cell 97, 825-828.
16. Gruss, O. J., Carazo-Salas, R. E., Schatz, C. A., Guarguaglini, G., Kast, K., Wilm, M., le Bot, N., Vernos, I., Karsenti, E. and Mattaj, I. W. (2001). Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. Cell 104, 83-93.
17. Harlow, E. and Lane, D. (1988). Antibodies: A Laboratory Manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
18. Haun, R. S., Tsai, S.-C., Adamik, R., Moss, J. and Vaughan, M. (1993). Effect of myristoylation on GTP-dependent binding of ADP-ribosylation factor to Golgi. J. Biol. Chem. 268, 7064-7068.
19. Heald, R. and Weis, K. (2000). Spindles get the ran around. Trends Cell Biol. 10, 1-4.
20. Hollenberg, S. M., Sternglanz, R., Cheng, P. F. and Weintraub, H. (1995). Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol. Cell. Biol. 15, 3813-3822.
21. Hong, J.-X., Lee, F.-J. S., Patton, W. A., Lin, C.-Y., Moss, J. and Vaughan, M. (1998). Phospholipid- and GTP-dependent activation of cholera toxin and phospholipase D by human ADP-ribosylation factor-like protein 1 (HARL1). J. Biol. Chem. 273, 15872-15876.
22. Huang, C.-F., Buu, L.-M., Yu, W.-L. and Lee, F.-J. S. (1999). Characterization of a novel ADP-ribosylation factor-like protein (yARL3) in Saccharomyces cerevisiae. J. Biol. Chem. 274, 3819-3827.
23. Ito, H., Fukuda, Y., Murata, K. and Kimura, A. (1983). Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153, 163-168.
24. Jacobs, S., Schilf, C., Fliegert, F., Koling, S., Weber, Y., Schurmann, A. and Joost, H.-G. (1999). ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARF family characterization by rapid nucleotide exchange and a nuclear localization signal. FEBS Lett. 456, 384-388.
25. James, T. C. and Elgin, S. C. (1986). Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene. Mol. Cell. Biol. 6, 3862-3872.
26. Kellum, R. and Alberts, B. M. (1995). Heterochromatin protein 1 is required for correct chromosome segregation in Drosophila embryos. J. Cell Sci. 108, 1419-1431.
27. Kourmouli, N., Theodoropoulos, P. A., Dialynas, G., Bakou, A., Politou, A. S., Cowell, I. G., Singh, P. B. and Georgatos, S. D. (2000). Dynamic associations of heterochromatin protein 1 with the nuclear envelope. EMBO J. 19, 6558-6568.
28. Le Douarin, B., Nielsen, A. J., Garnier, J. M., Ichinose, H., Jeanmougin, F., Losson, R. and Chambon, P. (1996). A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. EMBO J. 15, 6701-6715.
29. Lee, F.-J. S., Stevens, L. A., Kao, Y. L., Moss, J. and Vaughan, M. (1994). Characterization of a glucose-repressible ADP-ribosylation factor 3 (ARF3) from Saccharomyces cerevisiae. J. Biol. Chem. 269, 20931-20937.
30. Lee, F.-J. S., Huang, C.-F., Yu, W.-L., Buu, L.-M., Lin, C.-Y., Huang, M.-C., Moss, J. and Vaughan, M. (1997). Characterization of an ADP-ribosylation factor-like 1 protein in Saccharomyces cerevisiae. J. Biol. Chem. 272, 30998-31005.
31. Lin, C.-Y., Huang, P.-H., Liao, W.-L., Cheng, H.-J., Huang, C.-F., Kuo, J. C., Patton, W. A., Massenburg, D., Moss, J. and Lee, F.-J. S. (2000). ARL4, an ARF-like protein that is developmentally regulated and localized to nuclei and nucleoli. J. Biol. Chem. 275, 37815-37823.
32. Lorentz, A., Ostermann, K., Fleck, O. and Schmidt, H. (1994). Switching gene swi6, involved in repression of silent mating-type loci in fission yeast, encodes a homologue of chromatin-associated proteins from Drosophila and mammals. Gene 143, 139-143.
33. Lowe, S. L., Wong, S. H. and Hong, W. (1996). The mammalian ARF-like protein 1 (Arl1) is associated with the Golgi complex. J. Cell Sci. 109, 209-220.
34. Macia, E., Chabre, M. and Franco, M. (2001). Specificities for the small G proteins ARF1 and ARF6 of the guanine nucleotide exchange factors ARNO and EFA6. J Biol. Chem. 276, 24925-24930.
35. Misteli, T. (2001). Protein dynamics: implications for nuclear architecture and gene expression. Science 291, 843-847.
36. Moroianu, J., Blobel, G. and Radu, A. (1996). The binding site of karyopherin alpha for karyopherin beta overlaps with a nuclear localization sequence. Proc. Natl. Acad. Sci. USA 93, 6572-6576.
37. Moss, J. and Vaughan, M. (1995). Structure and function of ARF proteins: activators of cholera toxin and critical components of intracellular vesicular transport processes. J. Biol. Chem. 270, 12327-12330.
38. Moss, J. and Vaughan, M. (1998). Molecules in the ARF orbit. J. Biol. Chem. 273, 21431-21434.
39. Murzina, N., Verreault, A., Lane, E. and Stillman, B. (1999). Heterochromatin dynamics in mouse cells: interaction between chromatin assembly factor 1 and HP1 proteins. Mol. Cell 4, 529-540.
40. Nachury, M. V., Maresca, T. J., Salmon, W. C., Waterman-Storer, C. M., Heald, R. and Weis, K. (2001). Importin beta is a mitotic target of the small GTPase Ran in spindle assembly. Cell 104, 95-106.
41. Nielsen, A. L., Oulad-Abdelghani, M., Ortiz, J. A., Remboutsika, E., Chambon, P. and Losson, R. (2001). Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins. Mol. Cell 7, 729-739.
42. Northup, J. K., Sternweis, P. C. and Gilman, A. G. (1983). The subunits of the stimulatory regulatory component of adenylate cyclase. Resolution, activity, and properties of the 35,000-dalton (beta) subunit. J. Biol. Chem. 258, 11361-11368.
43. Olson, M. O., Dundr, M. and Szebeni, A. (2000). The nucleolus: an old factory with unexpected capabilities. Trends Cell Biol. 10, 189-196.
44. Pak, D. T., Pflumm, M., Chesnokov, I., Huang, D. W., Kellum, R., Marr, J., Romanowaski, P. and Botchan, M. R. (1997). Association of the origin recognition complex with heterochromatin and HP1 in higher eukaryotes. Cell 91, 311-323.
45. Sanger, F., Nicklen, S. and Coulson, A. R. (1977). DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467.
46. Saunders, W. S., Chue, C., Goebl, M., Craig, C., Clark, R. E, Powers, J. A., Eissenberg, J. C., Elgin, S. C. R., Rothfield, N. F. and Earnshaw, W. C. (1993). Molecular cloning of a human homologue of Drosophila heterochromatin protein HP1 using anti-centromere autoantibodies with anti-chromo specificity. J. Cell Sci. 104, 573-582.
47. Schreiber, E., Matthias, P., Muller, M. M. and Schaffner, W. (1989). Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res. 17, 6419.
48. Schurmann, A., Breiner, M., Becker, W., Huppertz, C., Kainulainen, H., Kentrup, H. and Joost, H.-G. (1994). Cloning of two novel ADP-ribosylation factor-like proteins and characterization of their differential expression in 3T3-L1 cells. J. Biol. Chem. 269, 15683-15688.
49. Seeler, J.-S., Marchio, A., Sitterlin, D., Transy, C. and Dejean, A. (1998). Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment. Proc. Natl. Acad Sci. USA 95, 7316-7321.
50. Singh, P. B. (1994). Molecular mechanisms of cellular determination: their relation to chromatin structure and parental imprinting. J. Cell Sci. 107, 2653-2668.
51. Singh, P. B., Miller, J. R., Pearce, J., Kotharty, R., Burton, R. D., Paro, R., James, T. C. and Gaunt, S. J. (1991). A sequence motif found in a Drosophila heterochromatin protein is conserved in animals and plants. Nucleic Acids Res. 19, 789-794.
52. Smith, S. A., Holik, P. R., Stevens, J., Melis, R., White, R. and Albertsen, H. (1995). Isolation and mapping of a gene encoding a novel human ADP-ribosylation factor on chromosome 17q12-q21. Genomics 28, 113-115.
53. Smothers, J. F. and Henikoff, S. (2000). The HP1 chromo shadow domain binds a consensus peptide pentamer. Curr. Biol. 10, 27-30.
54. Visintin, R. and Amon, A. (2000). The nucleolus: the magician's hat for cell cycle tricks. Curr. Opin. Cell Biol. 12, 372-377.
55. Weis, K., Mattaj, I. W. and Lamond, A. I. (1995). Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences. Science 268, 1049-1054.
56. Yang, C. Z., Heimberg, H., D'Souza-Schorey, C., Mueckler, M. M. and Stahl, P. D. (1998). Subcellular distribution and differential expression of endogenous ADP-ribosylation factor 6 in mammalian cells. J. Biol. Chem. 273, 4006-4011.
57. Ye, Q., Callebaut, I., Pezhman, A., Courvalin, J. C. and Worman, H. J. (1997). Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR. J. Biol. Chem. 272, 14983-14989.
58. Zhang, G.-F., Patton, W. A., Lee, F.-J. S., Liyanage, M., Han, J.-S., Rhee, S. G., Moss, J. and Vaughan, M. (1995). Different ARF domains are required for the activation of cholera toxin and phospholipase D. J. Biol. Chem. 270, 21-24.
59. Zhao, T. and Eissenberg, J. C. (1999) Phosphorylation of heterochromatin protein 1 by casein kinase II is required for efficient heterochromatin binding in Drosophila. J. Biol. Chem. 274, 15095-15100.