Biomolecule binding vs. anticancer activity: Reactions of Ru(arene)[(thio)pyr-(id)one] compounds with amino acids and proteins

Journal of Inorganic Biochemistry

Volumn 108, Issue , 2012, Pages 91-95

  Meier, Samuel M ^a   Hanif, Muhammad ^a,b   Kandioller, Wolfgang ^a   Keppler, Bernhard K ^a   Hartinger, Christian G ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b Research Platform Translational Cancer Therapy Research ^*  (Pakistan)

Author keywords

Adduct cleavage; Amino acids; Anticancer metallodrugs; Mass spectrometry; Ruthenium; Ubiquitin

Indexed keywords

AMINO ACID; ANTINEOPLASTIC AGENT; CHLORIDO(ETA 6 4 CYMENE)(2 METHYL 3 (OXO KAPPAO) 4H PYRAN 4 ONATO KAPPAO)RUTHENIUM(II); CHLORIDO(ETA 6 4 CYMENE)(2 METHYL 3 (OXO KAPPAO) 4H THIOPYRAN 4 ONATO KAPPAS)RUTHENIUM(II); CHLORIDO(ETA 6 4 CYMENE)[N [(ETHOXYCARBONYL)METHYL] 3 (OXO KAPPAO) 1H PYRID 2 ONATO KAPPAO]RUTHENIUM(II); METHIONINE; RUTHENIUM DERIVATIVE; UBIQUITIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; CANCER CELL CULTURE; CONFERENCE PAPER; CYTOTOXICITY; DRUG PROTEIN BINDING; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; HUMAN CELL;

AMINO ACIDS; ANTINEOPLASTIC AGENTS; PROTEIN BINDING; PROTEINS; RUTHENIUM COMPOUNDS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84858442826     PISSN: 01620134     EISSN: 18733344     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2011.08.011     Document Type: Conference Paper

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