SCOPUS 정보 검색 플랫폼

Volumn 50, Issue , 2012, Pages 129-139

1,3,4-Thiadiazole derivatives as selective inhibitors of iNOS versus nNOS: Synthesis and structure-activity dependence

(9) López Cara, Luisa C a Carrión, M Dora a Entrena, Antonio a Gallo, Miguel A a Espinosa, Antonio a López, Ana b Escames, Germaine b Acuña Castroviejo, Darío b Camacho, M Encarnación a

a UNIVERSITY OF GRANADA (Spain)

b UNIVERSITY OF GRANADA (Spain)

Author keywords

2,3 Dihydro 1,3,4 thiadiazole; 4,5 Dihydro 1H pyrazole; Inducible Nitric Oxide Synthase (iNOS); Inhibitors; Neuronal Nitric Oxide Synthase (nNOS)

Indexed keywords

1,3,4 THIADIAZOLE DERIVATIVE; 3 ACETHYL 5 (2 AMINO 5 CHLOROHENYL) 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 3 ACETHYL 5 (2 AMINO 5 METHOXYPHENYL) 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 3 ACETHYL 5 (2 AMINOPHENYL) 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 CHLORO) 3 CYCLOPROPYLCARBONYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 CHLOROPHENYL) 2,2 DIMETHYL 3 PENTANOYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 CHLOROPHENYL) 2,2 DIMETHYL 3 PROPYONYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 CHLOROPHENYL) 3 BENZOYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 CHLOROPHENYL) 3 BUTYRYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 CHLOROPHENYL) 3 CYCLOBUTANECARBONYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 CHLOROPHENYL) 3 CYCLOHEXANECARBONYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 CHLOROPHENYL) 3 CYCLOPENTANECARBONYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 METHOXYPHENYL) 2,2 DIMETHYL 3 PENTANOYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 METHOXYPHENYL) 2,2 DIMETHYL 3 PROPYONYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 METHOXYPHENYL) 3 BENZOYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 METHOXYPHENYL) 3 BUTYRYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 METHOXYPHENYL) 3 CYCLOBUTANECARBONYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 METHOXYPHENYL) 3 CYCLOHEXANECARBONYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 METHOXYPHENYL) 3 CYCLOPENTANECARBONYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINO 5 METHOXYPHENYL) 3 CYCLOPROPYLCARBONYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINOPHENYL) 2,2 DIMETHYL 3 PENTANOYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINOPHENYL) 2,2 DIMETHYL 3 PROPYONYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINOPHENYL) 3 BUTYRYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINOPHENYL) 3 CYCLOBUTYLCARBONYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINOPHENYL) 3 CYCLOHEXANECARBONYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINOPHENYL) 3 CYCLOPENTANECARBONYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; 5 (2 AMINOPHENYL) 3 CYCLOPROPYLCARBONYL 2,2 DIMETHYL 2,3 DIHYDRO 1,3,4 THIADIAZOLE; INDUCIBLE NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; ATOM; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; MOLECULAR DOCKING;

ENZYME INHIBITORS; HUMANS; MOLECULAR STRUCTURE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES;

EID: 84858439615 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2012.01.047 Document Type: Article

Times cited : (19)

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