Pyrazoles and pyrazolines as neural and inducible nitric oxide synthase (nNOS and iNOS) potential inhibitors (III)

European Journal of Medicinal Chemistry

Volumn 43, Issue 11, 2008, Pages 2579-2591

  Carrión, M Dora ^a   López Cara, Luisa C ^a   Camacho, M Encarnación ^a   Tapias, Víctor ^b   Escames, Germaine ^b   Acuña Castroviejo, Darío ^b   Espinosa, Antonio ^a   Gallo, Miguel A ^a   Entrena, Antonio ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b UNIVERSITY OF GRANADA   (Spain)

Author keywords

Benzoyl pyrazole; Benzoyl pyrazoline; Inducible nitric oxide synthase; Inhibition; Neural nitric oxide synthase

Indexed keywords

1 BENZYL 3 (2 AMINO 5 CHLOROBENZOYL) 1H PYRAZOLE 5 CARBOXYLIC ACID ETHYL ESTER; 3 (2 AMINO 5 CHLOROBENZOYL) 1 BENZYL 1H PYRAZOLE 5 CARBOXYLIC ACID ETHYL ESTER; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PYRAZOLE DERIVATIVE; PYRAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL TISSUE; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME INHIBITION; MALE; NONHUMAN; RAT; STRUCTURE ANALYSIS; SYNTHESIS;

ALKYLATION; ANIMALS; ENZYME INHIBITORS; MALE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; PROTEIN BINDING; PYRAZOLES; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 54049119707     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.01.014     Document Type: Article

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