Synthesis and evaluation of adenosine antagonist activity of a series of [1,2,4]triazolo[1,5-c]quinazolines

Chemical and Pharmaceutical Bulletin

Volumn 55, Issue 3, 2007, Pages 372-375

  Balo, Carmen ^a   López, Carmen ^a   Brea, José Manuel ^a   Fernández, Franco ^a   Caamaño, Olga ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Azo compound; Heterocycle; Hydrazide; Synthesis; Triazoloquinazoline

Indexed keywords

5 (2 AMINO 4 CHLOROPHENYL) 3 (2 FURYL) 1H 1,2,4 TRIAZOLE; 5 (2 AMINO 5 CHLOROPHENYL) 3 (2 FURYL) 1H 1,2,4 TRIAZOLE; 5 (2 AMINO 5 CHLOROPHENYL) 3 (2 PYRIDYL) 1H 1,2,4 TRIAZOLE; 5 (2 AMINO 5 CHLOROPHENYL) 3 (2 THIENYL) 1H 1,2,4 TRIAZOLE; 5 (2 AMINO 5 CHLOROPHENYL) 3 (3,4 DIMETHOXYPHENYL) 1H 1,2,4 TRIAZOLE; 5 (2 AMINO 5 CHLOROPHENYL) 3 PHENYL 1H 1,2,4 TRIAZOLE; 5 (2 AMINOPHENYL) 3 (2 FURYL) 1H 1,2,4 TRIAZOLE; 5 (3 AMINO 2 NAPTHYL) 3 (2 FURYL) 1H 1,2,4 TRIAZOLE; 5 ACETAMIDO 2 (2 FURYL)[1,2,4]TRIAZOLO[1,5 C]QUINAZOLINE; 5 AMINO 2 (2 FURYL)[1,2,4]TRIAZOLO[1,5 C]QUINAZOLINE; 5 AMINO 2 (2 FURYL)BENZO[G][1,2,4]TRIAZOLO[1,5 C]QUINAZOLINE; 5 AMINO 8 CHLORO 2 (2 FURYL)[1,2,4]TRIAZOLO[1,5 C]QUINAZOLINE; 5 AMINO 9 CHLORO 2 (2 FURYL)[1,2,4]TRIAZOLO[1,5 C]QUINAZOLINE; 5 AMINO 9 CHLORO 2 (2 PYRIDYL)[1,2,4]TRIAZOLO[1,5 C]QUINAZOLINE; 5 AMINO 9 CHLORO 2 (2 THIENYL)[1,2,4]TRIAZOLO[1,5 C]QUINAZOLINE; 5 AMINO 9 CHLORO 2 (3,4 DIMETHOXYPHENYL)[1,2,4]TRIAZOLO[1,5 C]QUINAZOLINE; 5 AMINO 9 CHLORO 2 PHENYL [1,2,4]TRIAZOLO[1,5 C]QUINAZOLINE; 9 CHLORO 2 (2 FURYL)[1,2,4]TRIAZOLO[1,5 C]QUINAZOLINE; [1,2,4]TRIAZOLO[1,5 C]QUINAZOLINE DERIVATIVE; ADENOSINE RECEPTOR BLOCKING AGENT; ANTHRANILOHYDRAZIDE; AROMATIC AMIDE; CHLORIDE; HYDRAZIDE DERIVATIVE; QUINAZOLINE DERIVATIVE; RECOMBINANT HUMAN ADENOSINE ALPHA2A RECEPTOR; RECOMBINANT HUMAN ADENOSINE ALPHA2B RECEPTOR; RECOMBINANT RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG ACTIVITY; DRUG BINDING; DRUG SCREENING; DRUG SYNTHESIS;

HUMANS; MOLECULAR STRUCTURE; QUINAZOLINES; RECEPTOR, ADENOSINE A2A; RECEPTOR, ADENOSINE A2B; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34047123085     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.55.372     Document Type: Article

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