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Volumn 23, Issue 6, 2012, Pages 1080-1094

Ezrin regulates microvillus morphogenesis by promoting distinct activities of Eps8 proteins

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; EPS8 PROTEIN; EZRIN; PROTEIN; UNCLASSIFIED DRUG;

EID: 84858411576     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E11-07-0588     Document Type: Article
Times cited : (39)

References (45)
  • 2
  • 5
    • 0024542907 scopus 로고
    • Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor
    • Bretscher A (1989). Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor. J Cell Biol 108, 921-930.
    • (1989) J Cell Biol , vol.108 , pp. 921-930
    • Bretscher, A.1
  • 6
    • 34848927902 scopus 로고    scopus 로고
    • The many faces of actin: Matching assembly factors with cellular structures
    • DOI 10.1038/ncb1007-1110, PII NCB1007-1110
    • Chhabra ES, Higgs HN (2007). The many faces of actin: matching assembly factors with cellular structures. Nat Cell Biol 9, 1110-1121. (Pubitemid 47500485)
    • (2007) Nature Cell Biology , vol.9 , Issue.10 , pp. 1110-1121
    • Chhabra, E.S.1    Higgs, H.N.2
  • 7
    • 0030763919 scopus 로고    scopus 로고
    • Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells
    • DOI 10.1083/jcb.138.2.423
    • Crepaldi T, Gautreau A, Comoglio PM, Louvard D, Arpin M (1997). Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells. J Cell Biol 138, 423-434. (Pubitemid 27323543)
    • (1997) Journal of Cell Biology , vol.138 , Issue.2 , pp. 423-434
    • Crepaldi, T.1    Gautreau, A.2    Comoglio, P.M.3    Louvard, D.4    Arpin, M.5
  • 9
    • 37049028154 scopus 로고    scopus 로고
    • Interaction of ezrin with the novel guanine nucleotide exchange factor PLEKHG6 promotes RhoG-dependent apical cytoskeleton rearrangements in epithelial cells
    • DOI 10.1091/mbc.E06-12-1144
    • D'Angelo R, Aresta S, Blangy A, Del Maestro L, Louvard D, Arpin M (2007). Interaction of ezrin with the novel guanine nucleotide exchange factor PLEKHG6 promotes RhoG-dependent apical cytoskeleton rearrangements in epithelial cells. Mol Biol Cell 18, 4780-4793. (Pubitemid 350246681)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.12 , pp. 4780-4793
    • D'Angelo, R.1    Aresta, S.2    Blangy, A.3    Del, M.L.4    Louvard, D.5    Arpin, M.6
  • 12
    • 0027179703 scopus 로고
    • Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals
    • Fazioli F, Minichiello L, Matoska V, Castagnino P, Miki T, Wong WT, Di Fiore PP (1993a). Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals. EMBO J 12, 3799-3808. (Pubitemid 23282756)
    • (1993) EMBO Journal , vol.12 , Issue.10 , pp. 3799-3808
    • Fazioli, F.1    Minichiello, L.2    Matoska, V.3    Castagnino, P.4    Miki, T.5    Wong, W.T.6    Di, F.P.P.7
  • 13
    • 0027196725 scopus 로고
    • The ezrin-like family of tyrosine kinase substrates: Receptor-specific pattern of tyrosine phosphorylation and relationship to malignant transformation
    • Fazioli F, Wong WT, Ullrich SJ, Sakaguchi K, Appella E, Di FP (1993b). The ezrin-like family of tyrosine kinase substrates: receptor-specific pattern of tyrosine phosphorylation and relationship to malignant transformation. Oncogene 8, 1335-1345. (Pubitemid 23129858)
    • (1993) Oncogene , vol.8 , Issue.5 , pp. 1335-1345
    • Fazioli, F.1    Wong, W.T.2    Ullrich, S.J.3    Sakaguchi, K.4    Appella, E.5    Di, F.P.P.6
  • 15
    • 1442285361 scopus 로고    scopus 로고
    • Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin
    • DOI 10.1083/jcb.200307032
    • Fiévet BT, Gautreau A, Roy C, Del Maestro L, Mangeat P, Louvard D, Arpin M (2004). Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin. J Cell Biol 164, 653-659. (Pubitemid 38282949)
    • (2004) Journal of Cell Biology , vol.164 , Issue.5 , pp. 653-659
    • Fievet, B.T.1    Gautreau, A.2    Roy, C.3    Del, M.L.4    Mangeat, P.5    Louvard, D.6    Arpin, M.7
  • 16
    • 77958500001 scopus 로고    scopus 로고
    • The scaffolding protein EBP50 regulates microvillar assembly in a phosphorylation-dependent manner
    • Garbett D, Lalonde DP, Bretscher A (2010). The scaffolding protein EBP50 regulates microvillar assembly in a phosphorylation-dependent manner. J Cell Biol 191, 397-413.
    • (2010) J Cell Biol , vol.191 , pp. 397-413
    • Garbett, D.1    Lalonde, D.P.2    Bretscher, A.3
  • 17
    • 0029121577 scopus 로고
    • Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site
    • Gary R, Bretscher A (1995). Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site. Mol Biol Cell 6, 1061-1075.
    • (1995) Mol Biol Cell , vol.6 , pp. 1061-1075
    • Gary, R.1    Bretscher, A.2
  • 18
    • 0034631843 scopus 로고    scopus 로고
    • Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane
    • DOI 10.1083/jcb.150.1.193
    • Gautreau A, Louvard D, Arpin M (2000). Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane. J Cell Biol 150, 193-203. (Pubitemid 30480237)
    • (2000) Journal of Cell Biology , vol.150 , Issue.1 , pp. 193-203
    • Gautreau, A.1    Louvard, D.2    Arpin, M.3
  • 19
    • 33748807734 scopus 로고    scopus 로고
    • Palladin binds to Eps8 and enhances the formulation of dorsal ruffles and podosomes in vascular smooth muscle cells
    • DOI 10.1242/jcs.03076
    • Goicoechea S, Arneman D, Disanza A, Garcia-Mata R, Scita G, Otey CA (2006). Palladin binds to Eps8 and enhances the formation of dorsal ruffles and podosomes in vascular smooth muscle cells. J Cell Sci 119, 3316-3324. (Pubitemid 44405217)
    • (2006) Journal of Cell Science , vol.119 , Issue.16 , pp. 3316-3324
    • Goicoechea, S.1    Arneman, D.2    Disanza, A.3    Garcia-Mata, R.4    Scita, G.5    Otey, C.A.6
  • 21
    • 15444367539 scopus 로고    scopus 로고
    • Src phosphorylates ezrin at tyrosine 477 and induces a phosphospecific association between ezrin and a kelch-repeat protein family member
    • DOI 10.1074/jbc.M411353200
    • Heiska L, Carpen O (2005). Src phosphorylates ezrin at tyrosine 477 and induces a phosphospecific association between ezrin and a kelch-repeat protein family member. J Biol Chem 280, 10244-10252. (Pubitemid 40395880)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.11 , pp. 10244-10252
    • Heiska, L.1    Carpen, O.2
  • 22
    • 77954732524 scopus 로고    scopus 로고
    • Molecular basis for the dual function of Eps8 on actin dynamics: Bundling and capping
    • Hertzog M et al. (2010). Molecular basis for the dual function of Eps8 on actin dynamics: bundling and capping. PloS Biol 8, e1000387.
    • (2010) PloS Biol , vol.8
    • Hertzog, M.1
  • 24
    • 0022721628 scopus 로고
    • Microinjected antibodies against the cytoplasmic domain of vesicular stomatitis virus glycoprotein block its transport to the cell surface
    • Kreis TE (1986). Microinjected antibodies against the cytoplasmic domain of vesicular stomatitis virus glycoprotein block its transport to the cell surface. EMBO J 5, 931-941.
    • (1986) EMBO J , vol.5 , pp. 931-941
    • Kreis, T.E.1
  • 25
    • 0026760578 scopus 로고
    • Identification of the two major epidermal growth factor-induced tyrosine phosphorylation sites in the microvillar core protein ezrin
    • Krieg J, Hunter T (1992). Identification of the two major epidermal growth factor-induced tyrosine phosphorylation sites in the microvillar core protein ezrin. J Biol Chem 267, 19258-19265.
    • (1992) J Biol Chem , vol.267 , pp. 19258-19265
    • Krieg, J.1    Hunter, T.2
  • 26
    • 77951763488 scopus 로고    scopus 로고
    • A regulated complex of the scaffolding proteins PDZK1 and EBP50 with ezrin contribute to microvillar organization
    • Lalonde DP, Garbett D, Bretscher A (2010). A regulated complex of the scaffolding proteins PDZK1 and EBP50 with ezrin contribute to microvillar organization. Mol Biol Cell 21, 1519-1529.
    • (2010) Mol Biol Cell , vol.21 , pp. 1519-1529
    • Lalonde, D.P.1    Garbett, D.2    Bretscher, A.3
  • 27
    • 79151470659 scopus 로고    scopus 로고
    • Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8
    • Manor U, Disanza A, Grati M, Andrade L, Lin H, Di Fiore PP, Scita G, Kachar B (2011). Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8. Curr Biol 21, 167-172.
    • (2011) Curr Biol , vol.21 , pp. 167-172
    • Manor, U.1    Disanza, A.2    Grati, M.3    Andrade, L.4    Lin, H.5    Di Fiore, P.P.6    Scita, G.7    Kachar, B.8
  • 28
    • 67649935286 scopus 로고    scopus 로고
    • Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF)
    • Menna E et al. (2009). Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF). PLoS Biol 7, e1000387.
    • (2009) PLoS Biol , vol.7
    • Menna, E.1
  • 30
    • 0020440480 scopus 로고
    • Nucleated polymerization of actin from the membrane-associated ends of microvillar filaments in the intestinal brush border
    • DOI 10.1083/jcb.95.1.223
    • Mooseker MS, Pollard TD, Wharton KA (1982). Nucleated polymerization of actin from the membrane-associated ends of microvillar filaments in the intestinal bush border. J Cell Biol. 95, 223-233. (Pubitemid 13197092)
    • (1982) Journal of Cell Biology , vol.95 , Issue.1 , pp. 223-233
    • Mooseker, M.S.1    Pollard, T.D.2    Wharton, K.A.3
  • 31
    • 38049019805 scopus 로고    scopus 로고
    • Spatial recruitment and activation of the Fes kinase by ezrin promotes HGF-induced cell scattering
    • Naba A, Reverdy C, Louvard D, Arpin M (2008). Spatial recruitment and activation of the Fes kinase by ezrin promotes HGF-induced cell scattering. EMBO J 27, 38-50.
    • (2008) EMBO J , vol.27 , pp. 38-50
    • Naba, A.1    Reverdy, C.2    Louvard, D.3    Arpin, M.4
  • 32
    • 0347360339 scopus 로고    scopus 로고
    • The eps8 Family of Proteins Links Growth Factor Stimulation to Actin Reorganization Generating Functional Redundancy in the Ras/Rac Pathway
    • DOI 10.1091/mbc.E03-06-0427
    • Offenhauser N, Borgonovo A, Disanza A, Romano P, Ponzanelli I, Iannolo G, Di Fiore PP, Scita G (2004). The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway. Mol Biol Cell 15, 91-98. (Pubitemid 38044946)
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.1 , pp. 91-98
    • Offenhauser, N.1    Borgonovo, A.2    Disanza, A.3    Romano, P.4    Ponzanelli, I.5    Iannolo, G.6    Di, F.P.P.7    Scita, G.8
  • 33
  • 34
    • 27644518354 scopus 로고    scopus 로고
    • Regulation of actin cytoskeleton architecture by Eps8 and Abi1
    • Roffers-Agarwal J, Xanthos JB, Miller JR (2005). Regulation of actin cytoskeleton architecture by Eps8 and Abi1. BMC Cell Biol 6, 36-50.
    • (2005) BMC Cell Biol , vol.6 , pp. 36-50
    • Roffers-Agarwal, J.1    Xanthos, J.B.2    Miller, J.R.3
  • 35
    • 2942622503 scopus 로고    scopus 로고
    • Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine
    • DOI 10.1016/j.devcel.2004.05.007, PII S1534580704001698
    • Saotome I, Curto M, McClatchey AI (2004). Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine. Dev Cell 6, 855-864. (Pubitemid 38745419)
    • (2004) Developmental Cell , vol.6 , Issue.6 , pp. 855-864
    • Saotome, I.1    Curto, M.2    McClatchey, A.I.3
  • 38
    • 0035802118 scopus 로고    scopus 로고
    • An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine
    • DOI 10.1083/jcb.200103146
    • Scita G, Tenca P, Areces LB, Tocchetti A, Frittoli E, Giardina G, Ponzanelli I, Sini P, Innocenti M, Di Fiore PP (2001). An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine. J Cell Biol 154, 1031-1044. (Pubitemid 34286182)
    • (2001) Journal of Cell Biology , vol.154 , Issue.5 , pp. 1031-1044
    • Scita, G.1    Tenca, P.2    Areces, L.B.3    Tocchetti, A.4    Frittoli, E.5    Giardina, G.6    Ponzanelli, I.7    Sini, P.8    Innocenti, M.9    Di, F.P.P.10
  • 41
    • 64549137929 scopus 로고    scopus 로고
    • Mst4 and ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex
    • ten Klooster JP et al. (2009). Mst4 and ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex. Dev Cell 16, 551-562.
    • (2009) Dev Cell , vol.16 , pp. 551-562
    • Ten Klooster, J.P.1
  • 42
    • 0037294987 scopus 로고    scopus 로고
    • In silico analysis of the EPS8 gene family: Genomic organization, expression profile, and protein structure
    • DOI 10.1016/S0888-7543(03)00002-8
    • Tocchetti A, Confalonieri S, Scita G, Di Fiore PP, Betsholtz C (2003). In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure. Genomics 81, 234-244. (Pubitemid 36298615)
    • (2003) Genomics , vol.81 , Issue.2 , pp. 234-244
    • Tocchetti, A.1    Confalonieri, S.2    Scita, G.3    Di, F.P.P.4    Betsholtz, C.5
  • 43
    • 77949757542 scopus 로고    scopus 로고
    • Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice
    • Tocchetti A et al. (2010). Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice. Plos One 5, e9468.
    • (2010) Plos One , vol.5
    • Tocchetti, A.1
  • 44
    • 0027933858 scopus 로고
    • Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family
    • Turunen O, Wahlström T, Vaheri A (1994). Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family. J Cell Biol 126, 1445-1453. (Pubitemid 24284609)
    • (1994) Journal of Cell Biology , vol.126 , Issue.6 , pp. 1445-1453
    • Turunen, O.1    Wahlstrom, T.2    Vaheri, A.3
  • 45
    • 0033612533 scopus 로고    scopus 로고
    • Direct involvement of ezrin/radixin/moesin (ERM)-binding membrane proteins in the organization of microvilli in collaboration with activated ERM proteins
    • DOI 10.1083/jcb.145.7.1497
    • Yonemura S, Tsukita S, Tsukita S (1999). Direct involvement of ezrin/radixin/moesin (ERM)- binding membrane proteins in the organization of microvilli in collaboration with activated proteins. J Cell Biol 145, 1497-1509. (Pubitemid 29310006)
    • (1999) Journal of Cell Biology , vol.145 , Issue.7 , pp. 1497-1509
    • Yonemura, S.1    Tsukita, S.2    Tsukita, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.