A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic β-cells

Biochemical Journal

Volumn 411, Issue 1, 2008, Pages 41-51

  Arden, Catherine ^a   Hampson, Laura J ^a   Huang, Guo C ^a   Shaw, James A M ^a   Aldibbiat, Ali ^a   Holliman, Graham ^a   Manas, Derek ^a   Khan, Salmaan ^b   Lange, Alex J ^b   Agius, Loranne ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

cell; 6 phosphofructo 2 kinase fructose 2,6 bisphosphatase (PFK 2 FBPase 2); Fructose 2,6 bisphosphate; Glucokinase; Insulin; Islets

Indexed keywords

BIODEGRADATION; CATALYSIS; CELL CULTURE; INSULIN; PROTEINS;

GLUCOKINASE; ISLETS;

ENZYME ACTIVITY;

6 PHOSPHOFRUCTO 2 KINASE; FRUCTOSE 2,6 BISPHOSPHATASE; GLUCOKINASE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; ISOENZYME; MESSENGER RNA; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE OVEREXPRESSION; GLYCOLYSIS; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

ANIMALS; DOWN-REGULATION; FRUCTOSEDIPHOSPHATES; GLUCOKINASE; GLYCOLYSIS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; ISOENZYMES; MALE; MICE; MICE, INBRED C57BL; PHOSPHOFRUCTOKINASE-2; RATS; RATS, WISTAR; RNA, SMALL INTERFERING;

RATTUS;

EID: 41649106843     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20070962     Document Type: Article

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