Conformational analysis of amyloid precursor protein fragment containing amino acids 667-676, and the effect of d-Asp and iso-Asp substitution at Asp 672 residue

Journal of Structural Biology

Volumn 177, Issue 3, 2012, Pages 621-629

  Shanmugam, Ganesh ^a,c   Polavarapu, Prasad L ^a   Láng, Emma ^b   Majer, Zsuzsa ^b  

^a VANDERBILT UNIVERSITY   (United States)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^c CENTRAL LEATHER RESEARCH INSTITUTE   (India)

Author keywords

Amyloid; APP; Circular dichroism; D Amino acid; Peptide; TFE

Indexed keywords

AMYLOID PRECURSOR PROTEIN; ASPARTIC ACID; BETA SECRETASE; DEXTRO ASPARTIC ACID; DIMETHYL SULFOXIDE; ISOASPARTIC ACID; SOLVENT; TRIFLUOROETHANOL; WATER;

ALPHA HELIX; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BETA SHEET; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; AMINO ACIDS; AMYLOID BETA-PROTEIN PRECURSOR; CIRCULAR DICHROISM; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION;

EID: 84858299061     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2012.01.012     Document Type: Article

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